Find 5 Star Hotels in São Tomé Island from $226

Check availability on São Tomé Island 5 Star Hotels

Next weekend
In two weeks

Compare São Tomé Island 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for São Tomé Island 5-star hotels

Pestana São Tomé

5.0 star property
8.0 out of 10, Very Good, (72)
"Good choice in São Tomé city."
$230 nightly
The price is $265
Sep 16 - Sep 17
Total with taxes and fees
Pestana São Tomé
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in São Tomé Island.
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

Praia Lagarto, São Tomé
$193 nightly
The price is $226 total per night from Sep 7 to Sep 8
$226 total
Sep 7 - Sep 8
Total with taxes and fees
Still don't see what you're looking for?
See all properties in São Tomé Island.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about São Tomé Island

Check out the local area in São Tomé Island—home to attractions like São Nicolau Waterfall and Pico São Tomé.

Top São Tomé Island Hotel Reviews

Find out more about São Tomé Island

Find out more about São Tomé Island

You enjoy the finer things in life, both at home and on vacation. Indulge your every whim on your next sabbatical. There's no reason to delay a getaway to São Tomé Island any longer. You'll join the multitudes of vacationers who have made São Tomé Island so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in São Tomé Island and get ready to enjoy the getaway of a lifetime.

Get a Great Deal on 5-Star Hotels in São Tomé Island

You'll have a fantastic time at one of these 5-star hotels. Exceptional service, delicious meals, and one-on-one attention are all ready for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you make reservations at that outstanding restaurant? A Swedish massage to help your cares fall away? Beautiful furniture, lip-smacking main courses, and even a hot tub in the bathroom...these hotels have it all.

You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in São Tomé Island are the perfect place to relax after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

Numerous visitors make São Tomé Island the place to vacation. Why not join their ranks? If you've been dreaming about a vacation set here, then go ahead and book it. A surge in interest means these great hotel rooms will go quickly. It's time to plan your next great escape. Opt for one of our São Tomé Island 5-star hotels today and settle down in the lap of luxury tomorrow.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

How much does it cost to stay in a 5-star hotel in São Tomé Island?
How much you pay for a 5-star hotel in São Tomé Island depends on factors such as when you plan to travel and the length of your stay. An insider tip for scoring the best deal? Use our pricing filters to compare the available hotels for your selected dates.

  • Search for the lowest price per night from $226

What makes a hotel 5 stars in São Tomé Island?
Faultless guest service is at the heart of every 5-star hotel in São Tomé Island. From the moment you enter the lobby, staff attend to your every need, whether arranging customized tours or providing a turn-down service. What's more, hotels have to offer upscale conveniences to be considered for a 5-star rating. These can include luxury bath products, spas or saunas, swimming pools, gastronomic kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in São Tomé Island?
Find an upscale retreat that includes your lodging, food, activities and entertainment in São Tomé Island with the help of our filters. Search for resorts with a 5-star rating and select the "All inclusive" filter. Make sure you check what's included in the price. That way, you can take full advantage of the premium perks on offer from the moment you step into the lobby.