Find 5 Star Hotels in São Tomé Island from $226
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Compare São Tomé Island 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for São Tomé Island 5-star hotels

Pestana São Tomé
Pestana São Tomé
Explore similar 4-star hotels

Omali São Tomé – Principe Collection
Learn more about São Tomé Island
Check out the local area in São Tomé Island—home to attractions like São Nicolau Waterfall and Pico São Tomé.

Top São Tomé Island Hotel Reviews
Find out more about São Tomé Island
Find out more about São Tomé Island
You enjoy the finer things in life, both at home and on vacation. Indulge your every whim on your next sabbatical. There's no reason to delay a getaway to São Tomé Island any longer. You'll join the multitudes of vacationers who have made São Tomé Island so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in São Tomé Island and get ready to enjoy the getaway of a lifetime.
Get a Great Deal on 5-Star Hotels in São Tomé Island
You'll have a fantastic time at one of these 5-star hotels. Exceptional service, delicious meals, and one-on-one attention are all ready for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you make reservations at that outstanding restaurant? A Swedish massage to help your cares fall away? Beautiful furniture, lip-smacking main courses, and even a hot tub in the bathroom...these hotels have it all.
You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in São Tomé Island are the perfect place to relax after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.
Your Getaway Starts Today
Numerous visitors make São Tomé Island the place to vacation. Why not join their ranks? If you've been dreaming about a vacation set here, then go ahead and book it. A surge in interest means these great hotel rooms will go quickly. It's time to plan your next great escape. Opt for one of our São Tomé Island 5-star hotels today and settle down in the lap of luxury tomorrow.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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