A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

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Our top choices for De Soto hotels

1. Radisson Hotel La Crosse

Radisson Hotel La Crosse
3.5 star property
Historic Downtown La Crosse
8.8 out of 10, Excellent, (1,082 reviews)
"Beautiful hotel with excellent view. Restaurant was superb and staff was very helpful."
United States
Kathleen
4 days ago
$110 nightly
The price is $126
Jul 26 - Jul 27
Total with taxes and fees
Radisson Hotel La Crosse

2. GrandStay Hotel & Suites

GrandStay Hotel & Suites
2.5 star property
Historic Downtown La Crosse
9.0 out of 10, Wonderful, (1,110 reviews)
"Clean room was nice. Breakfast was just ok in terms of free breakfast."
United States
Jacob
6 days ago
$91 nightly
The price is $105
Jul 26 - Jul 27
Total with taxes and fees
GrandStay Hotel & Suites

3. The Charmant Hotel

The Charmant Hotel
4.0 star property
Historic Downtown La Crosse
9.6 out of 10, Exceptional, (1,003 reviews)
"Loved our stay. We especially enjoyed our morning latte s."
United States
Jeff
5 days ago
$199 nightly
The price is $229
Jul 20 - Jul 21
Total with taxes and fees
The Charmant Hotel

4. Country Inn & Suites by Radisson, La Crosse, WI

Country Inn & Suites by Radisson, La Crosse, WI
2.5 star property
Northside
8.8 out of 10, Excellent, (1,001 reviews)
"I always look forward to staying there about 4 times a year."
United States
Riley
2 days ago
$78 nightly
The price is $90
Aug 2 - Aug 3
Total with taxes and fees
Country Inn & Suites by Radisson, La Crosse, WI

5. Pearl Street Hotel & Suites

Pearl Street Hotel & Suites
2.5 star property
Historic Downtown La Crosse
8.0 out of 10, Very Good, (531 reviews)
"Nice place good price great location."
United States
Moss
5 days ago
$88 nightly
The price is $101
Jul 26 - Jul 27
Total with taxes and fees
Pearl Street Hotel & Suites

6. Home2 Suites by Hilton La Crosse

Home2 Suites by Hilton La Crosse
3.0 star property
Historic Downtown La Crosse
9.4 out of 10, Exceptional, (918 reviews)
"The efficient kitchen was a surprise! Easy and clean property."
United States
Margaret
1 day ago
$98 nightly
The price is $112
Jul 26 - Jul 27
Total with taxes and fees
Home2 Suites by Hilton La Crosse

7. Waterfront Hotel

Waterfront Hotel
3.0 star property
Prairie Du Chien
9.2 out of 10, Wonderful, (952 reviews)
"Very good food. Pillows were excellent. The property was beautiful."
United States
Clark
1 day ago
$125 nightly
The price is $140
Jul 26 - Jul 27
Total with taxes and fees
Waterfront Hotel

8. Gundersen Hotel & Suites

Gundersen Hotel & Suites
2.5 star property
Powell-Poage-Hamilton
9.4 out of 10, Exceptional, (1,004 reviews)
"The staff interaction was excellent. Assisted us with great customer service."
United States
Chris
27 days ago
$122 nightly
The price is $141
Jul 30 - Jul 31
Total with taxes and fees
Gundersen Hotel & Suites

9. Scenic Valley Motel

Scenic Valley Motel
2.0 star property
Lansing
8.2 out of 10, Very Good, (133 reviews)
"Great nice clean place worth the cost."
United States
Michael
June 13th, 2026
$100 nightly
The price is $112
Jul 27 - Jul 28
Total with taxes and fees
Scenic Valley Motel

10. Hampton Inn & Suites La Crosse Downtown

Hampton Inn & Suites La Crosse Downtown
2.5 star property
Historic Downtown La Crosse
9.6 out of 10, Exceptional, (1,002 reviews)
"Breakfast was good with several choices."
United States
Beatriz
2 days ago
$106 nightly
The price is $122
Jul 26 - Jul 27
Total with taxes and fees
Hampton Inn & Suites La Crosse Downtown

11. Days Inn by Wyndham La Crosse

Days Inn by Wyndham La Crosse
2.0 star property
Northside
8.4 out of 10, Very Good, (33 reviews)
"Easy off and on from the interstate clean room newly renovated good shower."
United States
don
13 days ago
$73 nightly
The price is $84
Jul 30 - Jul 31
Total with taxes and fees
Days Inn by Wyndham La Crosse

12. Courtyard by Marriott La Crosse

Courtyard by Marriott La Crosse
3.0 star property
Historic Downtown La Crosse
9.0 out of 10, Wonderful, (600 reviews)
"Very nicely maintained hotel great views of the river."
United States
Kenny
3 days ago
$110 nightly
The price is $126
Jul 26 - Jul 27
Total with taxes and fees
Courtyard by Marriott La Crosse

13. AmericInn by Wyndham La Crosse Riverfront-Conference Center

AmericInn by Wyndham La Crosse Riverfront-Conference Center
3.0 star property
Northside
7.6 out of 10, Good, (1,000 reviews)
"It looked great. The pool was amazing for the kids."
United States
Haleigh
11 days ago
$91 nightly
The price is $105
Aug 2 - Aug 3
Total with taxes and fees
AmericInn by Wyndham La Crosse Riverfront-Conference Center

14. Super 8 by Wyndham La Crosse

Super 8 by Wyndham La Crosse
2.5 star property
Northside
8.0 out of 10, Very Good, (1,004 reviews)
"Service was great. Room was nice. Hottub was a great ammenity."
United States
Gilberto
5 days ago
$72 nightly
The price is $83
Aug 9 - Aug 10
Total with taxes and fees
Super 8 by Wyndham La Crosse

15. Best Western Plus LaCrescent / LaCrosse

Best Western Plus LaCrescent / LaCrosse
2.5 star property
La Crescent
9.2 out of 10, Wonderful, (584 reviews)
"Excellent breakfast spread. This place is just wonderful."
United States
Catherine
2 days ago
$98 nightly
The price is $109
Jul 26 - Jul 27
Total with taxes and fees
Best Western Plus LaCrescent / LaCrosse

16. Country Inn & Suites by Radisson, Prairie du Chien

Country Inn & Suites by Radisson, Prairie du Chien
3.0 star property
Prairie Du Chien
8.4 out of 10, Very Good, (1,000 reviews)
"Had a wonderful stay! The staff was very accommodating and helpful upon arrival."
United States
Kimberly
22 days ago
$99 nightly
The price is $110
Jul 26 - Jul 27
Total with taxes and fees
Country Inn & Suites by Radisson, Prairie du Chien

17. AmericInn by Wyndham Viroqua

AmericInn by Wyndham Viroqua
3.0 star property
Viroqua
8.2 out of 10, Very Good, (379 reviews)
"Room was clean and comfortable. Nothing fancy but exactly what we needed for the night."
United States
Melissa
3 days ago
$89 nightly
The price is $102
Aug 9 - Aug 10
Total with taxes and fees
AmericInn by Wyndham Viroqua

18. AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien
3.0 star property
Prairie Du Chien
8.0 out of 10, Very Good, (635 reviews)
"Clean room breakfast was good bed hard as a rock."
United States
Angela
20 days ago
$80 nightly
The price is $89
Jul 20 - Jul 21
Total with taxes and fees
AmericInn by Wyndham Prairie du Chien

19. Fairfield Inn & Suites by Marriott La Crosse Downtown

Fairfield Inn & Suites by Marriott La Crosse Downtown
3.0 star property
Historic Downtown La Crosse
9.2 out of 10, Wonderful, (839 reviews)
"Good breakfast menu and clean stayion."
United States
Linda
11 days ago
$101 nightly
The price is $116
Jul 26 - Jul 27
Total with taxes and fees
Fairfield Inn & Suites by Marriott La Crosse Downtown

20. Windsor Place Inn

Windsor Place Inn
2.0 star property
Southside
8.4 out of 10, Very Good, (1,004 reviews)
"Good location near food Culver s."
United States
Sara
19 days ago
$69 nightly
The price is $76
Jul 20 - Jul 21
Total with taxes and fees
Windsor Place Inn
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Where to stay in and around De Soto

Nestled in scenic Wisconsin, De Soto offers outdoor adventures and a welcoming atmosphere reminiscent of Florida. Explore nearby hot springs for relaxation, or embark on hiking trails that reveal stunning landscapes. Experience family-friendly activities and immerse yourself in the area's rich culture.

Lansing

Discover Lansing, a charming getaway perfect for families and nature enthusiasts looking for adventure. With its stunning outdoor scenery, visitors can explore the nearby French Creek Wildlife Management Area and enjoy various hiking trails. The picturesque lake and river provide a serene backdrop for relaxation. Located about 4 miles by car from De Soto, Lansing offers easy access to its attractions, making it a smart choice for your next vacation.

Retreat

Experience the charm of Retreat, a delightful hub for families and nature enthusiasts eager to explore the beauty of De Soto. With attractions like Big Lake for serene waterfront activities, the picturesque Romance Prairie State Natural Area for outdoor adventures, and the tranquil Romance Woods for peaceful strolls, there’s something for everyone. Nestled in De Soto, Retreat offers easy access to these local gems, making it a smart choice for your next getaway.

Ferryville

If you are a family or nature enthusiast, look no further than Ferryville, which features stunning outdoor scenery and adventure opportunities. The area offers easy access to beautiful spots like Big Lake and local landmarks such as the Immaculate Conception - Wexford Church and Black Hawk Bridge, perfect for exploration. With Ferryville located about 7 miles by car from De Soto, it makes for a seamless travel experience. Choosing Ferryville for your stay ensures a memorable getaway immersed in nature.

New Albin

Immerse yourself in New Albin, where outdoor enthusiasts can easily access stunning natural attractions and family-friendly activities. This charming city offers a perfect blend of adventure and relaxation, with highlights like Big Lake for fishing fun, the serene Romance Prairie State Natural Area for hiking, and the Lansing Wildlife Management Area for nature exploration. Located about 17 miles by car from De Soto, New Albin makes an excellent choice for a weekend getaway, ensuring memorable experiences for all visitors.

Eagle Mountain

Travelers seeking a family-friendly getaway will find Eagle Mountain to be the ideal base for their vacation, featuring stunning natural scenery and outdoor activities. Nestled about 10 miles by car from De Soto, this charming neighborhood offers access to a recreational area, golf course, and nearby attractions like Big Lake and the Black Hawk Bridge. With visitor numbers peaking in July and September to October, Eagle Mountain is a smart choice for those looking to immerse themselves in Wisconsin's beautiful landscapes.

Stay near popular attractions around De Soto

Discover the charm of De Soto, where outdoor adventures and stunning scenery await. Explore local parks, relax by the lake, and indulge in family-friendly activities. Whether you're seeking romance or adventure, De Soto offers an unforgettable experience for every traveler.

Learn more about De Soto

Perched along the Mississippi River, De Soto offers scenic overlooks where bald eagles soar above the water during migration seasons. Explore the nearby Blackhawk Park for fishing and camping, or time your visit for the annual Labor Day celebration with its small-town parade and festivities.

A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

Top De Soto Hotel Reviews

More cheap stays in De Soto

Hotels in De Soto with star-rating

Find out more about De Soto

Top reasons to visit De Soto

  • Outdoor Adventure: De Soto is perfect for outdoor enthusiasts, offering hiking trails and beautiful landscapes for exploration.
  • Fishing Opportunities: Enjoy fantastic fishing experiences with local species available in the area's waters.
  • Scenic Drives: Drive along the Wisconsin Great River Road for breathtaking views of the region's natural beauty.
  • Bluff Country Exploration: Discover the enchanting Bluff Country, ideal for hiking and outdoor activities.
  • Charming Accommodations: Choose from a variety of unique hotels, including pet-friendly and agritourism options.

Find great hotels near De Soto

Explore a variety of hotel accommodations in De Soto, Wisconsin, catering to adventurous travelers and those seeking a unique historic-themed experience. Whether you prefer pet-friendly options or agritourism properties, De Soto offers a range of choices to suit your needs. Discover the best hotels and enjoy a memorable stay in this charming area.

  • AmericInn by Wyndham Viroqua: AmericInn by Wyndham Viroqua is a budget-friendly hotel offering a comfortable stay with a guest rating of 8.2 out of 10. Located 19 miles from De Soto, this property is perfect for business travelers seeking convenience. Guests appreciate the modern amenities, including complimentary breakfast, an indoor pool, and a well-equipped business center. The welcoming atmosphere and attentive staff make it a reliable choice for those looking for a practical stay with essential comforts.
  • Boarders Inn & Suites by Cobblestone Hotels – Waukon: With a guest rating of 8.0 out of 10, Boarders Inn & Suites by Cobblestone Hotels – Waukon is a 3.5-star hotel situated 18 miles from De Soto. Ideal for business travelers, this hotel combines comfort and functionality. Guests enjoy spacious rooms equipped with microwaves and refrigerators, a complimentary breakfast, and a fitness center to maintain their routine. The inviting lobby and friendly staff create an atmosphere that enhances both relaxation and productivity during your stay.
  • Driftless Escape – Secluded Luxury Lodge on Stream with Hot Tub: Driftless Escape is a hidden gem located just 6 miles from De Soto, boasting an impressive guest rating of 9.6 out of 10. This lodge is designed for adventure enthusiasts and pet owners, offering a unique blend of luxury and nature. Guests can indulge in outdoor activities such as hiking, fishing, and swimming, while the hot tub provides a perfect way to unwind after a day of exploration. With a pet-friendly policy and a serene riverside setting, this lodge is ideal for those looking to connect with nature and enjoy a tranquil getaway.

Where to stay in and around De Soto

De Soto, Wisconsin, is a haven for outdoor enthusiasts and families alike, offering stunning views and friendly local charm. Explore the scenic Wisconsin Great River Road, where breathtaking landscapes await. Discover the enchanting Bluff Country, perfect for hiking and adventure. Enjoy the rich history and welcoming atmosphere of the De Soto area, making your vacation both memorable and enriching. Whether you're seeking adventure or relaxation, De Soto has something for everyone.

  • Lansing: Located a mere 4 miles from De Soto, Lansing is a charming city that attracts visitors year-round, with peak travel times in June to July and September. Known for its outdoor adventures and stunning scenery, Lansing offers a host of recreational activities, including hiking trails and access to beautiful lakes and rivers. The nearby national state park provides a perfect backdrop for outdoor enthusiasts looking to immerse themselves in nature. Whether you’re seeking a peaceful retreat or an adrenaline-filled adventure, Lansing has something for everyone.
  • Retreat: Nestled within the area of De Soto, Retreat is a quaint village that welcomes travelers at any time of the year. With peak visitor numbers in July to August and October, Retreat is an ideal spot for those seeking a romantic getaway or family-friendly entertainment. The village features educational and recreational areas, including playgrounds perfect for kids. Visitors can enjoy picturesque lakes and a community-focused event conference venue, making it a great choice for both relaxation and social gatherings.
  • Ferryville: Just 7 miles away from De Soto, Ferryville is a delightful city that draws visitors with its natural beauty and adventure opportunities. The travel experience here is rich with outdoor activities, particularly during the summer months of June to July and in September. With access to hiking trails and recreational areas, Ferryville is perfect for those who love to explore the great outdoors. The proximity to rivers and lakes, along with the nearby national state park, ensures that every visit is filled with scenic views and memorable experiences.

Things to do in De Soto

De Soto, Wisconsin, is perfect for outdoor enthusiasts seeking adventure and stunning scenery. Visitors can explore a variety of recreational areas, enjoy hiking trails, and access beautiful landscapes. Fishing is also a highlight, offering fantastic opportunities to catch local species. Whether you're looking to hike, fish, or simply enjoy nature, De Soto has something for everyone to experience and enjoy.

Shopping

In De Soto, you'll find charming local shops offering unique gifts and souvenirs. If you're up for a drive, check out the nearby Prairie du Chien Shopping Center for more variety, including big-name retailers and local boutiques to enhance your shopping experience.

Recreation

In De Soto, the Driftless Wellness Retreat provides rejuvenating yoga sessions and holistic spa treatments amidst serene surroundings. Explore the scenic landscapes while hiking or biking along the Mississippi River, and enjoy peaceful moments by the water, making it an ideal destination for relaxation and self-care.

Adventure

Explore the scenic beauty of the Mississippi River on a kayaking adventure, offering stunning views and a chance to spot local wildlife. For hiking enthusiasts, the nearby Kickapoo Valley Reserve has trails that meander through lush landscapes, providing a perfect opportunity for outdoor exploration and photography.

Nightlife

In De Soto, the nightlife is laid-back yet inviting, with local bars like The River View Tavern offering live music and friendly atmospheres. For a more casual vibe, enjoy drinks at the nearby Riverside Restaurant, where you can unwind and savor the scenic views of the Mississippi River.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for De Soto

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in De Soto are November to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in De Soto is Monday. The most expensive day to stay in De Soto is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and eco-friendly hotels currently available. To find the best prices and deals, sort the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your De Soto hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near De Soto

De Soto, Wisconsin, is a great destination for outdoor enthusiasts and families seeking adventure and scenic beauty. With popular attractions like parks and urban spaces, visitors can immerse themselves in nature while enjoying cultural experiences. Whether you're looking to relax in a park or explore local libraries, there's something for everyone in and around De Soto.

  • Immaculate Conception - Wexford Church: Located 11 miles from De Soto, this charming church offers a serene atmosphere steeped in culture. Its beautiful architecture and peaceful surroundings make it a perfect spot for reflection and appreciation of local history.
  • Big Lake: Just 2 miles away, Big Lake is a picturesque destination for outdoor lovers. Whether you're looking to relax on the beach, enjoy a romantic sunset, or take in the stunning scenery, this lake has something for everyone.
  • Romance Woods: Situated 11 miles from De Soto, Romance Woods is perfect for adventure seekers. Explore its lush trails and immerse yourself in nature, making it an ideal spot for hiking and discovering the beauty of the forest.

Best time to go to De Soto

The best time to visit De Soto can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in De Soto falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in De Soto falls in January, visitor numbers are slightly low and weather is mostly cloudy with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January17.4°F (-8.1°C)No RainMostly CloudySlightly LowSlightly Low
February19.8°F (-6.8°C)No RainMostly CloudyAverageAverage
March34.5°F (1.4°C)Light RainMostly CloudyAverageAverage
April45.5°F (7.5°C)Light RainMostly CloudySlightly HighAverage
May57.9°F (14.4°C)Light RainMostly SunnySlightly HighSlightly High
June68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
July72.0°F (22.2°C)Light RainMostly SunnySlightly HighAverage
August70.3°F (21.3°C)Light RainMostly SunnyAverageAverage
September63.3°F (17.4°C)Light RainMostly SunnyAverageSlightly High
October49.6°F (9.8°C)Light RainMostly SunnyAverageSlightly High
November36.7°F (2.6°C)Light RainMostly SunnySlightly LowSlightly Low
December25.0°F (-3.9°C)Light RainMostly CloudySlightly LowSlightly Low

The nearest major airports for your trip to De Soto

When planning your trip to De Soto, Wisconsin, you can consider three major airports. La Crosse Municipal Airport (LSE) is the closest, located 31 miles away. Good hotel options nearby include The Charmant Hotel and Radisson Hotel La Crosse, both about 4 miles from the airport, with 24-hour shuttle services available. Rochester International Airport (RST) is 73 miles away, with hotels like The Towers At Kahler Grand Hotel and EVEN Hotel Rochester, both 8 miles from the airport. Finally, Dane County Regional Airport (MSN) is 95 miles away, featuring hotels like The Edgewater and DoubleTree by Hilton Madison East, both conveniently accessible with various transportation services.

Frequently asked questions

What is the best area to stay in De Soto?
The best area to stay in De Soto is directly within the village center, particularly along or near Main Street.

This area serves as the heart of De Soto, offering convenient access to local businesses and the Mississippi River. Main Street, also known as Wisconsin Highway 35, runs through the village and provides easy navigation. While De Soto is a small community, staying in the village center means you're close to everything it has to offer.

Families looking for a laid-back experience will find this area suitable. The proximity to the Mississippi River provides opportunities for outdoor activities like fishing or enjoying the river views.
What are the most romantic hotels in De Soto for couples?
For a romantic getaway in De Soto, consider The River View Lodge Sun Set Views over Looking Mississippi River Romantic.

This highly-rated lodge boasts a superb 10.0 review score and offers several features ideal for couples. Guests can enjoy private outdoor spaces such as a deck, patio, porch, or balcony, some of which provide beautiful sunset views over the Mississippi River. The lodge also includes a kitchen, a hot tub, and a fireplace, creating a cozy and intimate atmosphere for a special stay.
What are the best hotels in De Soto near Mississippi River?
For hotels in De Soto near the Mississippi River, The River View Lodge Sun Set Views over Looking Mississippi River Romanticis a good option.

This lodge, with a superb 10.0 rating, offers a relaxed stay with amenities such as a kitchen, a deck or patio, a porch or lanai, and a balcony, all of which provide opportunities to enjoy the views. It is located 267.3 miles from the Mississippi River.
When is the best time to go to De Soto?
The best time to visit De Soto is during the summer and fall months, from June through October, when the weather is most pleasant for outdoor activities.

Summer in De Soto offers warm temperatures ideal for exploring the Mississippi River and surrounding bluffs. This is a great time for families to enjoy fishing, boating, or picnicking in the local parks along the riverfront. The longer daylight hours also allow for more time to discover the area's natural beauty.

Fall brings cooler temperatures and the vibrant colors of autumn foliage, making it a particularly scenic time for couples. Driving along the Great River Road offers picturesque views, and local orchards often open for apple picking.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in De Soto.
How much is the nightly rate at a De Soto hotel?
Prices for hotels in De Soto often vary, but you can find a great deal from $68 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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