Find hotels in De Soto, WI from $51

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Compare 226 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Waterfront Hotel
3 out of 5
113 S Main St, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $101 per night from Mar 26 to Mar 27
$101
per night
Mar 26 - Mar 27
25.81 mi from city center
9/10 Wonderful! (357 reviews)
"Favorite hotel! Highly recommend."

Reviewed on Mar 20, 2023

Waterfront Hotel
Country Inn & Suites by Radisson, Prairie du Chien, WI
3 out of 5
1801 Cabela's Lane, Prairie Du Chien, WI, 53821
Fully refundable
The price is $94 per night from Mar 30 to Mar 31
$94
per night
Mar 30 - Mar 31
24.16 mi from city center
8.2/10 Very Good! (699 reviews)
"The staff was very friendly and the hotel was neat and clean. Enjoyed our stay."

Reviewed on Mar 6, 2023

Country Inn & Suites by Radisson, Prairie du Chien, WI
AmericInn by Wyndham Prairie du Chien
2 out of 5
37502 Us Highway 35 And 18 S, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $67 per night from Mar 30 to Mar 31
$67
per night
Mar 30 - Mar 31
27.81 mi from city center
8/10 Very Good! (263 reviews)
"The room was very nice AND clean. Bathroom was nice and large. Loved it had great water pressure for the shower. The pool area was very nice, however it did not seem like the heat was turned up. We all had to put on sweatshirts. The whirlpool was not operating which was disappointing to us. Overall, ..."

Reviewed on Dec 19, 2022

AmericInn by Wyndham Prairie du Chien

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Microtel Inn & Suites by Wyndham Prairie du Chien
2.5 out of 5
1833 S Marquette Road, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $61 per night from Mar 26 to Mar 27
$61
per night
Mar 26 - Mar 27
27.35 mi from city center
8.4/10 Very Good! (353 reviews)
"Breakfast was terrible. Room was nice."

Reviewed on Feb 4, 2023

Microtel Inn & Suites by Wyndham Prairie du Chien
Quality Inn & Suites
2.5 out of 5
37268 US Highway 18, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $58 per night from Mar 26 to Mar 27
$58
per night
Mar 26 - Mar 27
27.51 mi from city center
7.6/10 Good! (179 reviews)
"The room was clean. The pool area was cleans. But not enough towels in the pool area"

Reviewed on Jan 13, 2023

Quality Inn & Suites
Cobblestone Inn & Suites - Marquette/Prairie du Chien
2.5 out of 5
100 North Street, Marquette, IA, 52158
Fully refundableReserve now, pay when you stay
The price is $100 per night from Mar 26 to Mar 27
$100
per night
Mar 26 - Mar 27
26.12 mi from city center
8.8/10 Excellent! (709 reviews)
"Great staff, clean room, nice area."

Reviewed on Mar 12, 2023

Cobblestone Inn & Suites - Marquette/Prairie du Chien
Super 8 by Wyndham Prairie Du Chien
2 out of 5
1930 S Marquette Rd, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $51 per night from Apr 5 to Apr 6
$51
per night
Apr 5 - Apr 6
27.47 mi from city center
8.2/10 Very Good! (372 reviews)
"The staff was very friendly & accommodating. Not very quiet being right off a main road but we were not there to be in the room. A nice small town with friendly people & lots to do out in nature"

Reviewed on Feb 22, 2023

Super 8 by Wyndham Prairie Du Chien
Trickling Waters Retreat
3 out of 5
516 Fifth Street Court, Marquette, IA, 52158
Fully refundableReserve now, pay when you stay
The price is $79 per night from Mar 27 to Mar 28
$79
per night
Mar 27 - Mar 28
26.4 mi from city center
9.6/10 Exceptional! (164 reviews)
Great getaway
"Wonderful experience-will return again!"

Reviewed on Oct 17, 2022

Trickling Waters Retreat
Thornwood Cottage is the perfect little get away
Lansing, IA
The price is $75 per night from Mar 29 to Mar 30
$75
per night
Mar 29 - Mar 30
8.99 mi from city center
9.8/10 Exceptional! (62 reviews)
Perfect!
"My wife and I love this place. We've stayed here multiple times. It is cozy and comfortable and has everything you need. The bathroom is in the other house as to listing says, but that bathroom is nicer than our bathroom at home! If you have mobility issues, you may have trouble getting up to the ..."

Reviewed on Feb 27, 2023

Thornwood Cottage is the perfect little get away
Windsor Place Inn
2 out of 5
1936 Marquette Road South, Prairie Du Chien, WI, 53821
Fully refundableReserve now, pay when you stay
The price is $59 per night from Mar 26 to Mar 27
$59
per night
Mar 26 - Mar 27
27.46 mi from city center
8.2/10 Very Good! (571 reviews)
"Very clean and well kept."

Reviewed on Dec 11, 2022

Windsor Place Inn
Badger Cabin w/ Hot Tub Jacuzzi
Lansing, IA
The price is $75 per night from Mar 26 to Mar 27
$75
per night
Mar 26 - Mar 27
4.69 mi from city center
Badger Cabin w/ Hot Tub Jacuzzi
White Pines w/ Hot Tub & Swimming Pond
Lansing, IA
The price is $55 per night from Mar 26 to Mar 27
$55
per night
Mar 26 - Mar 27
7.4 mi from city center
4/10 (1 review)
Outdated Cabin
"I usually am a very nice person but this cabin rental was awful! Definitely not what I saw online it was dirty and I had to dust when I got there it was that bad! Also took awhile for the hot tub to get warm and my husband and I never enjoyed it luckily the weather was nice for us to enjoy getting ..."

Reviewed on Mar 1, 2023

White Pines w/ Hot Tub & Swimming Pond
Village Creek Lodge 6 bedrooms, Hot Tub, Pool
Lansing, IA
The price is $75 per night from Mar 27 to Mar 28
$75
per night
Mar 27 - Mar 28
6.32 mi from city center
6/10 (1 review)
Great location!
"The location of the property was amazing! The town of Lansing is adorable. For winter activities there is a ski mountain 40 min away and lots of trails for hikes. The property itself was good, a little dusty in some areas of the house and the listing photos are out dated, but overall good. Plenty ..."

Reviewed on Jan 17, 2023

Village Creek Lodge 6 bedrooms, Hot Tub, Pool
Sunset Lodge w/ Hot Tub
Harpers Ferry, IA
The price is $145 per night from Apr 16 to Apr 17
$145
per night
Apr 16 - Apr 17
19.74 mi from city center
9/10 Wonderful! (2 reviews)
Peaceful friends getaway
"Perfect winter getaway for us. Spacious, peaceful, ideal location."

Reviewed on Mar 6, 2023

Sunset Lodge w/ Hot Tub
Yellow River Lodge w/ outdoor Hot Tub Jacuzzi & Pool
Waterville, IA
The price is $95 per night from Mar 29 to Mar 30
$95
per night
Mar 29 - Mar 30
21.25 mi from city center
7/10 Good! (8 reviews)
Much needed R&R
"Could've been a bit cleaner, & there were several small things in need of repair, but for the price you can't really complain. Overall though it was exactly what we needed...some much deserved R&R."

Reviewed on Dec 9, 2022

Yellow River Lodge w/ outdoor Hot Tub Jacuzzi & Pool
Boulder Run w/ Hot Tub & Pool
Lansing, IA
The price is $75 per night from Mar 26 to Mar 27
$75
per night
Mar 26 - Mar 27
5.9 mi from city center
Boulder Run w/ Hot Tub & Pool
Cozy Log Cabin next to the Mississippi River
Harpers Ferry, IA
15.99 mi from city center
9.6/10 Exceptional! (39 reviews)
"It was adorable very clean & nice. Host was excellent"

Reviewed on Mar 13, 2023

Get rates
Cozy Log Cabin next to the Mississippi River
2 bedroom open concept house 5 minutes from the Mississippi River.
Prairie du Chien, WI
The price is $110 per night from Mar 26 to Mar 27
$110
per night
Mar 26 - Mar 27
26.48 mi from city center
9/10 Wonderful! (2 reviews)
Awesome place
"Great place. Good communication. Will definitely be back."

Reviewed on Feb 20, 2023

2 bedroom open concept house 5 minutes from the Mississippi River.
River Valley Cabin
Lansing, IA
The price is $325 per night from Mar 27 to Mar 28
$325
per night
Mar 27 - Mar 28
9.02 mi from city center
10/10 Exceptional! (52 reviews)
Fantastic Very Welcoming Cabin
"Great place for 8 of us to enjoy our ice fishing trip. Great place for relaxing and enjoying good times. Absolutely beautiful estate for relaxing and enjoying life."

Reviewed on Feb 27, 2023

River Valley Cabin
Walnut Ridge Cabin w/ Hot Tub
Waterville, IA
The price is $75 per night from Mar 28 to Mar 29
$75
per night
Mar 28 - Mar 29
16.18 mi from city center
Walnut Ridge Cabin w/ Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto hotels information

Number of reviews
3,834
Accommodation
226 hotels
Lowest Price
$51
Highest Price
$325

Frequently asked questions

What's the best place for a stay in De Soto?

Based on Expedia's traveler preferences, The Driftless Cottage - A Modern Cabin in the Woods is a top place to stay in De Soto. Other good choices for your trip include Secluded Cabin Just Minutes From The Mississippi River!! and Moonlight Ridge- Rustic Cabin. See all available top hotels, or vacation rentals in De Soto.

What's the top vacation rental that De Soto has to offer?

4 BR home with breathtaking View of the Mississippi River: This highly rated vacation home rental in De Soto is located on a river and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For more information about updating your trip to De Soto or cancelling it, go to https://www.expedia.com/service/.

What are some accommodations with pools in De Soto?

Gundersen Hotel & Suites: Offers buffet, an indoor pool, and complimentary wired Internet access. View all hotels with pools in De Soto.

What is the best accommodation for staying close to La Crosse Municipal Airport (LSE)?

Country Inn & Suites by Radisson, La Crosse, WI is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from La Crosse Municipal Airport. Other options near the airport are AmericInn by Wyndham La Crosse Riverfront-Conference Center and Motel 6 La Crosse, WI.

What is staying in De Soto like?

Visitors are sure to enjoy all that De Soto has to offer. In De Soto, there are 17 hotels and other accommodations to choose from. Find out more about De Soto.

What are the top places to visit in De Soto?

A favorite place to visit is Mississippi River. You'll also find Yellow River State Forest and Mount Hosmer Park in the area. Check out what more to see and do in Expedia's De Soto guide.

What's the weather like in De Soto?

The hottest months are usually July and August with an average temp of 70Ā°F, while the coldest months are January and February with an average of 24Ā°F. The snowiest months in De Soto are December, January, March, and February, with each month seeing an average of 8 inches of snowfall.

Recent reviews of De Soto hotels
Expedia verified reviews

  • Gundersen Hotel & Suites

    Gundersen Hotel & Suites

    5/5 Excellent
    "I stayed at Gunderson Hotel the night before I had surgery at Gunderson Clinic. This place was very nice....super clean. I did not expect this. Very impressed "
    A verified traveler stayed at Gundersen Hotel & Suites
    Posted 5 days ago
    Gundersen Hotel & Suites