Title: Visit Isola: 2026 Travel Guide for Isola, Mississippi | Expedia.com [Hotels in Isola](https://expedia.com/Isola-Hotels.d553248635975852319.Travel-Guide-Hotels)[Vacation Rentals in Isola](https://expedia.com/Isola-Vacation-Rentals.d553248635975852319.Travel-Guide-VacationRentals)[Car Rentals in Isola](https://expedia.com/Car-Rentals-In-Isola.d553248635975852319.Car-Rental-Guide)[Isola Vacation Packages](https://expedia.com/Isola.d553248635975852319.Destination-Travel-Guides) # Isola, MS ## Travel Guide ## Visit Isola ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248635975852319) - Isola Hotel Deals - Vacation Rentals in Isola ![Americas Best Value Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/84a898ad_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Americas Best Value Inn Indianola 1015 Highway 82 E Indianola MS Fully refundableReserve now, pay when you stay $65 nightly $71 total Mar 8 - Mar 9 Total with taxes and fees Stay at this motel in Indianola. Enjoy free WiFi, free parking, and room service. Popular attractions Indianola Pecan House and Fletcher Park are located ... 7.6/10 Good! (212 reviews) The beds were loud and the tub would not drain. Reviewed on Feb 19, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=9942&PinnedHotelID=9942&HadPinnedHotel=true®ionId=553248635975852319) ![Quality Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/de59d956_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Inn Indianola 910 Highway 82 E Indianola MS $68 nightly $75 total Mar 22 - Mar 23 Total with taxes and fees Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ... 7.2/10 Good! (132 reviews) I left before my check out because it was that bad The breakfast was the worst I ever seen in my life. They had sandwiches that they got from Walmart to put in the microwave orange juice. You have to pull in a glass just pathetic waste of money. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=4155&PinnedHotelID=4155&HadPinnedHotel=true®ionId=553248635975852319) ![Super 8 by Wyndham Indianola](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/38d6e30e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham Indianola 601 Highway 82 W Indianola MS $86 nightly $94 total Mar 22 - Mar 23 Total with taxes and fees Book a stay at this business-friendly hotel in Indianola. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Minnie Cox Park and Henry M. ... 7.2/10 Good! (381 reviews) Clean room, cereal muffins waffles for breakfast,hot coffee friendly staff Reviewed on Feb 22, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=214874&PinnedHotelID=214874&HadPinnedHotel=true®ionId=553248635975852319) [See all 8 properties in Isola](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=553248635975852319) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![X Marks the Spot 3 Bedrooms, 4 Beds, 1 bathroom House. Newly remodeled.](https://images.trvl-media.com/lodging/101000000/100610000/100606700/100606658/7913b023_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### X Marks the Spot 3 Bedrooms, 4 Beds, 1 bathroom House. Newly remodeled. Hollandale MS Stay at this vacation home in Hollandale. Enjoy laundry facilities and air conditioning. Popular attraction Leroy Percy State Park is located nearby. 10/10 Exceptional! (1 review) Very nice! So very clean and nice. Reviewed on Aug 5, 2024 [](https://expedia.com/Hollandale-Hotels-X-Marks-The-Spot3-Bedrooms.h100606658.Hotel-Information) ![Charming 3-bedroom house with WiFi and AC in Hollandale](https://images.trvl-media.com/lodging/114000000/113940000/113935900/113935812/f2865e45_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Charming 3-bedroom house with WiFi and AC in Hollandale Hollandale MS Stay at this vacation home in Hollandale. Enjoy free WiFi, laundry facilities, and patios. Popular attraction Leroy Percy State Park is located nearby. [](https://expedia.com/Hollandale-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Hollandale.h113935812.Hotel-Information) [See all properties in Isola](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635975852319&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Isola hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=2026-03-07&endDate=2026-03-08)[Mar 7 - Mar 8](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=2026-03-07&endDate=2026-03-08) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=2026-03-08&endDate=2026-03-09)[Mar 8 - Mar 9](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=2026-03-08&endDate=2026-03-09) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975852319&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) ## Cities near Isola ![Dockery Plantation blues museum in Cleveland, MS.](https://images.trvl-media.com/place/7485/00523147-624c-4e4e-8480-5dccdd088654.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Cleveland ![Live oak tree with moss and pond in background.](https://images.trvl-media.com/place/7540/ef086d4e-36a5-45e2-b238-7aab6a6bd17f.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Greenwood ![Driving through Mississippi, I had a chance to stop at Yazoo City! I instantly regretted traveling on a holiday because the downtown area looked like so much fun but everything was closed. The building are painted in bright colors and there are plywood guitars with different designs painted on them all along both sides of the road. There’s also a children’s area where a mural has been painted. ](https://images.trvl-media.com/place/7787/12bd0203-a33b-45fe-985a-82e02c114d8d.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Yazoo City ![Cotton Plant](https://images.trvl-media.com/place/8190/9993952e-16ec-4344-bdda-4943ab912844.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Indianola - Cities near Isola - Places of interest [Cleveland](https://expedia.com/Cleveland.dx7485)[Greenwood](https://expedia.com/Greenwood.dx7540)[Itta Bena](https://expedia.com/Itta-Bena.dx7786)[Yazoo City](https://expedia.com/Yazoo-City.dx7787)[Indianola](https://expedia.com/Indianola.dx8190)[Lake Village](https://expedia.com/Lake-Village.dx177941)[Choctaw](https://expedia.com/Choctaw.dx6060582)[Greenville](https://expedia.com/Greenville.dx6135541)[Hollandale](https://expedia.com/Hollandale.dx6352630)[Leland](https://expedia.com/Leland.dx6352635)[Belzoni](https://expedia.com/Belzoni.dx3000444033)[Anguilla](https://expedia.com/Anguilla.dx553248635125972568) - [Eagle Lake ](https://expedia.com/Eagle-Lake-Belzoni.d909911540212424704.Vacation-Attraction) - [BB King Museum ](https://expedia.com/BB-King-Museum-Indianola.d6306651.Vacation-Attraction)