Fine food and fine art are two musts that should be on any sophisticated traveler's itinerary. Get a taste for the latter at House of Piero della Francesca, where you'll find plenty of inspiring pieces to whet your artistic appetite.
You're spoiled for sightseeing choice in Sansepolcro. House of Piero della Francesca is a good place to start here, but there are numerous other interesting sights to visit. La Madonna di Citerna di Donatello, Madonna del Parto, and Aboca Museum are close to the collection of precious artworks and will round out your day nicely.