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Our top choices for Santa Cruz hotels

A buffet with various fruits, vegetables, and beverages.
A person using a laptop in a hotel room with a bed, a chair, and a small table.
Exterior
A bar area with a curved counter, shelves with bottles, and hanging wine glasses.

1. ibis Medellin

ibis Medellin
El Poblado
United States
Yuliana
$55 nightly
$55 total
Nov 1 - Nov 2
ibis Medellin
A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.
A multi-story building with a modern architectural design, featuring large windows and a brick facade.
Private kitchen
A hotel room with a bed, a small table with chairs, a coffee maker, and a view of the city through the window.

2. Urbit Social Lofts

Urbit Social Lofts
Laureles
United States
Richard
$49 nightly
$49 total
Oct 14 - Oct 15
Urbit Social Lofts
A swimming pool with tiled edges, surrounded by lounge chairs and palm trees.
A bedroom with a wooden ceiling, a brick wall, a bed with pillows, a nightstand, and a chair.
A traditional wooden building with a sloped roof and a balcony.
A spacious indoor venue with high ceilings and natural light, featuring wooden tables and chairs, and various floral arrangements.

3. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
Rionegro
United States
Mabel Angela Frias
$38 nightly
$38 total
Oct 19 - Oct 20
Autenthico Sajonia Hotel Aeropuerto
A bedroom with a large bed, a chair, and a view through a glass door.
A modern glass structure with a roof, surrounded by a well-maintained lawn and trees.
A modern bedroom with a large bed, wooden headboard, bedside tables, and a view of greenery through a window.
A garden pathway with various plants and a palm tree.

4. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
Rionegro
Australia
Cristina
$69 nightly
$69 total
Oct 23 - Oct 24
Isak Hotel & Golf Airport
A rooftop pool area with a breakfast setup, including plates, cups, and juice.
A multi-story building with a brick facade, surrounded by lush greenery and other high-rise buildings.
A hotel lobby with a reception desk, a large potted plant, a check-in counter, and a seating area.
An outdoor patio area with tables and chairs, a large canopy, and a brick wall.

5. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
El Poblado
United States
Christian Alvarez
$74 nightly
$74 total
Oct 18 - Oct 19
Hotel Dann Carlton Belfort Medellin
A modern kitchen with a central island, bar area, and seating.
A modern living room with a sectional sofa, a neon 'RECORDS' sign, a shelving unit with shoes, and a hanging light fixture.
A modern living room with a sofa, a chair, a coffee table, and a potted plant.
A swimming pool with a water fountain, large windows, and a modern ceiling design.

6. Loma, Medellin, a Tribute Portfolio Hotel

Loma, Medellin, a Tribute Portfolio Hotel
El Poblado
United States
Solymar
$92 nightly
$92 total
Oct 16 - Oct 17
Loma, Medellin, a Tribute Portfolio Hotel
A hotel sign with a sun emblem, a modern glass building, and flags.
A rooftop terrace with lounge chairs and a large umbrella, overlooking a cityscape at dusk.
A neatly arranged bedroom with a bed, bedside table, and a desk with a chair.
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.

7. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
San Diego
United States
Domingo
$93 nightly
$93 total
Oct 13 - Oct 14
La Quinta by Wyndham Medellin
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.
A modern hotel entrance with a prominent sign reading "Fairfield by Marriott" and a staircase leading to the lobby.
A modern kitchen with a central island, bar stools, and a hanging plant.
A modern kitchen area with wooden cabinets, a countertop, and a fruit bowl.

8. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
Sabaneta
United States
Michael
$77 nightly
$77 total
Nov 1 - Nov 2
Fairfield by Marriott Medellin Sabaneta
A modern bar with a long counter, shelves with decorative items, and a coffee machine.
A modern hotel lobby with a reception desk, seating area, and large windows.
A city view from a high-rise room with a chair and a table.
A restaurant with multiple tables and chairs, large windows offering a view of mountains and cityscape, and indoor plants.

9. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
El Poblado
United States
Oscar
$139 nightly
$139 total
Nov 6 - Nov 7
Novotel Medellín El Tesoro
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.
A bar area with a green wall, bar stools, and a counter with a bartender.
A casino with multiple slot machines and chairs arranged in rows.
A spacious indoor dining area with multiple tables and chairs, large windows offering city views, and visible air ducts on the ceiling.

10. Hotel Dorado La 70

Hotel Dorado La 70
Laureles
United States
Gregson
$91 nightly
$91 total
Oct 24 - Oct 25
Hotel Dorado La 70
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.
Gift shop
A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.
A modern hotel room with a large bed, a sitting area with a table and chairs, a bathtub, and a balcony with a view of the city.

11. Eutopiq Hotel

Eutopiq Hotel
Laureles
United States
Luis Alfonso
$77 nightly
$77 total
Oct 12 - Oct 13
Eutopiq Hotel
A modern hotel room with a large bed, bedside table with a lamp, a desk with a chair, and a potted plant.
A reception area with a wooden slatted wall, a marble reception desk, and a ceiling with exposed beams and lighting.
A spacious dining area with wooden tables and chairs, surrounded by shelves with plants.
A hallway with wooden flooring, a potted plant, and a wall-mounted artwork of leaves.

12. Moa Select

Moa Select
Laureles
United States
Jorge
$55 nightly
$55 total
Oct 27 - Oct 28
Moa Select
A modern building entrance with glass doors, a wooden ceiling, and potted plants.
A gym with wooden floors, weight racks, and exercise equipment.
A modern hotel room with a large bed, bedside tables, a bench, a potted plant, and a sliding door closet.
An indoor seating area with tables and chairs, a large sign reading 'PERGAMINO,' and a wooden wall design.

13. The Cut Hotel

The Cut Hotel
El Poblado
United States
Arturo
$51 nightly
$51 total
Oct 15 - Oct 16
The Cut Hotel
A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.
A modern lobby with glass walls, a tiled floor, and a potted plant.
A brick building with a sign reading "ibis budget."
A modern reception area with a black counter, a digital display, and a wall decorated with food and drink illustrations.

14. ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
Itagüí
United States
Jose
$45 nightly
$45 total
Oct 25 - Oct 26
ibis budget Medellín Itagüí Metro
A modern reception area with a glass door entrance, a reception desk, and seating arrangements.
A modern interior with multiple ceiling lights, large windows, and a visible air conditioning unit.
A gym with exercise equipment, a punching bag, and a view of the city through large windows.
A hotel room with a bed, a tray with a bottle and glasses, a red pillow, and a view of the outside through sheer curtains.

15. Arame Hotel

Arame Hotel
Envigado
United States
David
$73 nightly
$73 total
Nov 8 - Nov 9
Arame Hotel
A hotel entrance with a modern design, featuring a staircase leading to the lobby, a chandelier, and a sign indicating the hotel's name.
A modern hotel room with a large bed, a flat-screen TV, a dark-colored sofa, and a large window with curtains.
A gym with a treadmill, a small table with a bottle and a towel, and a spa area with candles and towels.
A hotel dining area with multiple tables and chairs, a skylight, and artwork on the walls.

16. Hotel Egina Medellín

Hotel Egina Medellín
Laureles - Estadio
United States
Chad
$66 nightly
$66 total
Nov 2 - Nov 3
Hotel Egina Medellín
A modern outdoor pool area with a wooden deck, lounge chairs, and a table with umbrellas.
A modern meeting room with a wooden table, black chairs, and a potted plant.
A bar area with stools, shelves with bottles, and a counter.
A modern hotel lobby with a long reception desk, seating area, and a large window.

17. Movich Hotel Las Lomas

Movich Hotel Las Lomas
Rionegro
Canada
Waleed
$132 nightly
$132 total
Nov 8 - Nov 9
Movich Hotel Las Lomas
A row of modern, glass-roofed buildings with a garden in front featuring various colorful flowers.
A room with two beds, a table, and a chair. There is a window with curtains, and a view of greenery outside.
A modern room with two beds, a large window with curtains, and artwork on the wall.
A small, single-story building with a sloped roof, numbered 1 and 2, indicating separate units. A concrete staircase leads to a door with a glass panel, revealing a bed and a wall-mounted light fixture.

18. NEW STAR CENTER

NEW STAR CENTER
Rionegro
United States
Julienne
$62 nightly
$62 total
Oct 12 - Oct 13
NEW STAR CENTER
A multi-level outdoor pool area with tiered wooden structures, lounge chairs, and umbrellas.
A modern building with a unique circular wooden balcony design, surrounded by greenery and a clear sky.
A hotel room with a large bed, a wooden headboard, a bedside table, a mirror, and a view of the cityscape.
A modern reception area with a green sofa, a reception desk, and a large, circular ceiling light fixture.

19. Heiss Hotel By Jalo

Heiss Hotel By Jalo
El Poblado
United States
Mario
$75 nightly
$75 total
Nov 2 - Nov 3
Heiss Hotel By Jalo
A reflective pool with a cityscape and mountains in the background.
A library with bookshelves, a ladder, a round table, and a potted plant.
A modern hotel room with a large bed, a wooden desk, a black curtain, a brick accent wall, and a balcony with plants.
A modern bedroom with a large bed, a bench, and a brick wall.

20. Los Patios Cool Living

Los Patios Cool Living
Laureles
United States
Emilio
$66 nightly
$66 total
Oct 14 - Oct 15
Los Patios Cool Living
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Top Santa Cruz Hotel Reviews

Moa Select

Moa Select

10/10 Excellent
"I had an excellent stay! I was recovering from surgery, and the staff made me feel comfortable and well cared for. Their kindness, attention, and willingness to help made my recovery so much easier. I’m truly grateful for their hospitality and highly recommend this hotel."
Katherine 5-night trip
Posted 2 hours ago
Moa Select
Blues Suites Medellin

Blues Suites Medellin

10/10 Excellent
"The best breakfast ever. Service was amazing. Loved"
Jacqueline 8-night trip
Posted 6 hours ago
Blues Suites Medellin
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Excellente hotel para una fabulosa estadia 100%ok"
Vincenzo 1-night trip
Posted 23 hours ago
Dann Carlton Medellin Hotel
Marquee Hotel

Marquee Hotel

10/10 Excellent
"Location location location! was the best everything is right outside the hotel food, coffee many restaurants n shops. The hotel itself was very clean and up to date. The pool area was the best part n had the most amazing views of medellin. The breakfast was great had a few options to choose from made to order. And even tho its in a busy area and loud that wasnt an issue for me i slept just fine. Can't wait to be back"
Maryela 4-night trip
Posted 1 day ago
Marquee Hotel
Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"Hotel Súper lindo, el buffet espectacular, lo recomiendo con los ojos cerrados"
Pacifico 1-night trip
Posted 1 day ago
Hotel San Fernando Plaza
Faranda Collection Medellin, a Member of Radisson Individuals

Faranda Collection Medellin, a Member of Radisson Individuals

10/10 Excellent
"Excelente hotel en Medellín, super céntrico cerca de centros comerciales, estaciones de metro y fácil ubicación. El hotel está hermoso, el personal super amable, la comida riquísima, el servicio del cuarto espectacular y las amenidades todo un lujo. 100% volvería y recomendadisimo"
Abner Adrian Medina 4-night trip
Posted 2 days ago
Faranda Collection Medellin, a Member of Radisson Individuals
Hotel Dorado La 70

Hotel Dorado La 70

8/10 Good
"Los desayunos son muy simple, siempre el mismo menú. Los huevos siempre fríos independientemente a hora que vayas. Las frutas siempre es un corte de papaya y sandía . El área para desayunar es algo incómoda. Los empleados son muy atentos"
Adrian 2-night trip
Posted 2 days ago
Hotel Dorado La 70
V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent
"todo estuvo excelente"
Yoelis Zoe Leon 4-night trip
Posted 3 days ago
V Grand Hotel, a member of Radisson Individuals
Hotel BH El Poblado

Hotel BH El Poblado

10/10 Excellent
"Excelente servicio, limpieza y cerca de los principales comercios"
Daniel Rodriguez 4-night trip
Posted 4 days ago
Hotel BH El Poblado

More cheap stays in Santa Cruz

Hotel Casa Malibú

Hotel Casa Malibú

Calle 32F 66 c 57 Medellín Medellin
$21 nightly
$21 total
Oct 14 - Oct 15
4.8/10 (3 reviews)
Hotel Casa Malibú
Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
$24 nightly
$24 total
Oct 22 - Oct 23
8.4/10 Very Good! (165 reviews)
Hostal Lleras Calle 8 - Hostel
Hotel Ofix - Laureles

Hotel Ofix - Laureles

79-86 Calle 44 Medellín
$35 nightly
$35 total
Oct 23 - Oct 24
Hotel Ofix - Laureles
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
$38 nightly
$38 total
Oct 19 - Oct 20
Autenthico Sajonia Hotel Aeropuerto
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
$58 nightly
$58 total
Nov 10 - Nov 11
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
$77 nightly
$77 total
Oct 19 - Oct 20
Masaya Medellin

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $21 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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