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Sep 21 - Sep 22
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Sep 22 - Sep 23
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Sep 25 - Sep 27
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Our top choices for Santa Cruz hotels

A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.
A casino with multiple slot machines and chairs arranged in rows.
A bar area with a green wall, bar stools, and a counter with a bartender.
A spacious indoor dining area with multiple tables and chairs, large windows offering city views, and visible air ducts on the ceiling.

1. Hotel Dorado La 70

Hotel Dorado La 70
Laureles
United States
Gregson
$74 nightly
$74 total
Sep 27 - Sep 28
Hotel Dorado La 70
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.
A multi-story hotel with a prominent 'EUTOPIO' sign, featuring a modern architectural design with a mix of brick and glass facades, and balconies with greenery.
A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.

2. Eutopiq Hotel

Eutopiq Hotel
Laureles
United States
Luis Alfonso
$66 nightly
$66 total
Sep 29 - Sep 30
Eutopiq Hotel
A modern interior with a circular window, a seating area with a cushioned bench, and a small table.
A compact room with a desk, chair, coffee maker, and a trash bin.
A modern bathroom with a round mirror, a sink, a toilet, and a glass-enclosed shower.
A hotel room with a bed, a desk with a chair, a television, and a window with curtains.

3. Urbit Garden Hotel

Urbit Garden Hotel
Laureles
United States
Elio Rafael
$71 nightly
$71 total
Sep 25 - Sep 26
Urbit Garden Hotel
A hotel sign with a sun emblem, a modern glass building, and flags.
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.
A rooftop terrace with lounge chairs and a large umbrella, overlooking a cityscape at dusk.
A neatly arranged bedroom with a bed, bedside table, and a desk with a chair.

4. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
San Diego
United States
Domingo
$95 nightly
$95 total
Sep 26 - Sep 27
La Quinta by Wyndham Medellin
A buffet with various fruits, vegetables, and beverages.
A modern outdoor seating area with a mix of tables and sofas, surrounded by lush green plants and a metal fence.
A person using a laptop in a hotel room with a bed, a chair, and a small table.

5. ibis Medellin

ibis Medellin
El Poblado
United States
Yuliana
$44 nightly
$44 total
Oct 17 - Oct 18
ibis Medellin
A hotel lobby with glass doors, a reception desk, and a chandelier.
A hotel entrance with a modern design, featuring a staircase leading to the lobby, a chandelier, and a sign indicating the hotel's name.
A restaurant setting with a bar area in the background, featuring wine bottles and a TV screen.
A bar area with a brick wall, a flat-screen TV, and a variety of bottles and glasses.

6. Hotel Egina Medellín

Hotel Egina Medellín
Laureles - Estadio
United States
Alfonso
$58 nightly
$58 total
Oct 15 - Oct 16
Hotel Egina Medellín
A spacious lobby with a central staircase, large potted plants, and a chandelier.
A restaurant with a glass ceiling, wooden furniture, and a fireplace.
A restaurant with a panoramic city view, high ceilings, and modern furnishings.
A rooftop pool with lounge chairs and umbrellas, surrounded by greenery and tall buildings.

7. Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
El Poblado
United States
Lisa Marie
$108 nightly
$108 total
Sep 27 - Sep 28
Dann Carlton Medellin Hotel
A reflective pool with a cityscape and mountains in the background.
A modern hotel room with a large bed, a wooden desk, a black curtain, a brick accent wall, and a balcony with plants.
A library with bookshelves, a ladder, a round table, and a potted plant.
A modern bedroom with a large bed, a bench, and a brick wall.

8. Los Patios Cool Living

Los Patios Cool Living
Laureles
United States
Emilio
$63 nightly
$63 total
Sep 28 - Sep 29
Los Patios Cool Living
An indoor dining area with multiple tables and chairs, a high ceiling with wooden slats, and large windows offering views of buildings outside.
A modern bar area with a central island, bar stools, and pendant lighting.
A person seated by a window with a cityscape view, holding a plate.
A modern bar area with a circular bar, multiple stools, and potted plants.

9. Tequendama Hotel Medellín

Tequendama Hotel Medellín
Laureles - Estadio
United States
Marilyn
$76 nightly
$76 total
Oct 23 - Oct 24
Tequendama Hotel Medellín
A multi-level outdoor pool area with tiered wooden structures, lounge chairs, and umbrellas.
A hotel room with a wooden vanity, a bed, a large window with a mountain view, and a flat-screen TV mounted on the wall.
A modern reception area with a green sofa, a reception desk, and a large, circular ceiling light fixture.
A hotel room with a large bed, a wooden headboard, a bedside table, a mirror, and a view of the cityscape.

10. Heiss Hotel By Jalo

Heiss Hotel By Jalo
El Poblado
United States
Marcus E
$50 nightly
$50 total
Oct 23 - Oct 24
Heiss Hotel By Jalo
A modern hotel room with a large bed, a separate bathroom with a bathtub, and a large window offering a city view.
A rooftop pool area with a hot tub, lounge chairs, and exercise equipment.
A modern bedroom with a large bed, a separate sofa, a bathtub, and a vanity with a mirror.
A spacious indoor area with multiple tables and chairs, a seating area with a cushioned bench, and large windows providing natural light and a view of greenery outside.

11. Hotel Lincoln

Hotel Lincoln
Laureles
United States
Isaac
$63 nightly
$63 total
Sep 23 - Sep 24
Hotel Lincoln
A couple in a hot tub with a bottle of wine, surrounded by modern wall lighting and a potted plant.
A bar area with shelves of wine bottles and glasses, decorated with green foliage.
A tall building with a modern design, featuring large windows and a sign that reads "SPRING SELECT EST 2025".
A restaurant with booths, tables, and chairs, featuring a modern design with plants and pendant lighting.

12. Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
Laureles
United States
Norberto
$51 nightly
$51 total
Sep 25 - Sep 26
Hotel Ryo 74B Suites by Growing Group
A modern bedroom with a large bed, a small table, and a chair.
A reception area with a modern design, featuring a white reception desk, a white sofa, and a mural of tropical plants.
A modern hotel room with a large bed, a desk with chairs, a TV, and a view of the outdoors.
A modern kitchen with a built-in island, wooden cabinets, and a bar stool.

13. Firenze Lofts

Firenze Lofts
La América
United States
Carlos
$46 nightly
$46 total
Oct 7 - Oct 8
Firenze Lofts
A restaurant with wooden tables and benches, a bar area, and large windows offering a view of greenery.
A modern hotel room with a large balcony, a dining table, and chairs.
A spacious lobby with large windows, a central pillar, and seating arrangements.

14. V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
El Poblado
Canada
Juan
$96 nightly
$96 total
Oct 23 - Oct 24
V Grand Hotel, a member of Radisson Individuals
A modern bar with a long counter, shelves with decorative items, and a coffee machine.
A modern hotel lobby with a reception desk, seating area, and large windows.
A restaurant with multiple tables and chairs, large windows offering a view of mountains and cityscape, and indoor plants.
A city view from a high-rise room with a chair and a table.

15. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
El Poblado
United States
catalina
$125 nightly
$125 total
Oct 23 - Oct 24
Novotel Medellín El Tesoro
A restaurant with a small indoor water feature, wooden tables, and chairs.
A modern bedroom with a bed, a desk, and a chair. There is a window with a view of trees and buildings.
A cozy reading nook with a cushioned bench, a wooden bookshelf, and a table with chairs.
A modern building with a geometric facade, large windows, and a visible entrance with a door and window.

16. beminimal Jardines

beminimal Jardines
Laureles
United States
Franklin
$92 nightly
$92 total
Sep 23 - Sep 24
beminimal Jardines
A building with a bar area, outdoor seating, and a visible name 'LUSSAC'.
A hallway with wooden paneling, a chair, and a polished marble floor.
A gym with various exercise equipment, a treadmill, and a weight bench.
A buffet with various food items and utensils.

17. Hotel Park 10

Hotel Park 10
El Poblado
United States
Wilfred
$122 nightly
$122 total
Sep 23 - Sep 24
Hotel Park 10
A modern restaurant with multiple tables and chairs, a counter with staff, and large windows with a view of greenery.
An outdoor patio with a striped umbrella, a table with chairs, and potted plants.
A hotel room with two beds, a desk, and a window.
A gym with a neon sign reading 'GYM MODE ON' and exercise equipment.

18. Hotel Santiago de Arma

Hotel Santiago de Arma
Rionegro
United States
Mario
$124 nightly
$124 total
Sep 26 - Sep 27
Hotel Santiago de Arma
A pathway leading to a building with a modern design, surrounded by lush greenery and trees.
A modern bathroom with a glass-enclosed shower, a white toilet, and a wooden vanity.
A wooden desk with a shelf unit beside it, a door, and a light switch on the wall.
A pathway flanked by black shipping containers, with greenery and a clear sky.

19. Hotel centro logistico del norte

Hotel centro logistico del norte
Bello
$25 nightly
$25 total
Oct 23 - Oct 24
Hotel centro logistico del norte
A rooftop pool with a waterfall, white lounge chairs, and a view of the cityscape.
A modern building with a sign reading "Calle de Flora."
An outdoor cafe area with round tables and chairs, a bar counter, and greenery.
A bar area with stools, a counter, and shelves with various items.

20. Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo
El Poblado
United States
Norka
$90 nightly
$90 total
Sep 23 - Sep 24
Calle Flora Hotel by Jalo
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Top Santa Cruz Hotel Reviews

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

10/10 Excellent
"Great stay! The front desk staff was very attentive, friendly, and accommodating. The room was clean, nice, and cozy, and the 24/7 security was definitely a plus. The location was also great and very convenient. Overall, I had a really good experience and would definitely stay here again!"
Jose 4-night trip
Posted 2 hours ago
Hashtag 98 Hotel By Jalo
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"Modern and very well mantained property with an amazing ambience in a prime location of El Poblado. Friendly and very attentive staff. Excellent breakfast."
Brenda 5-night trip
Posted 3 hours ago
The Click Clack Hotel Medellin
Heiss Hotel By Jalo

Heiss Hotel By Jalo

8/10 Good
"Well the bar up stairs was no open most of the time. This staff is very friendly and you can talk to them with through whatsapp, and they will solve your problems. Their rooms are nice. The balconies are nice. The only problem is that it is very loud in the room. You can hear everything in the hallway at all times all the way down to the lobby. The stupid tv seems to have been on a timer, and he kept turning on in the middle of the night full blast but thats not really the hotel fault. They give you a pair of ear plugs for a reason. Also the breakfast its a pass. Overall great location to take ubers and move around"
Hoguer 2-night trip
Posted 4 hours ago
Heiss Hotel By Jalo
The Charlee Hotel

The Charlee Hotel

10/10 Excellent
"Excellent Location"
Patrick 7-night trip
Posted 4 hours ago
The Charlee Hotel
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

8/10 Good
"The stay was good but the breakfast was not. Even if you order fresh eggs always cold and the coffee too."
Ivette 4-night trip
Posted 5 hours ago
Novotel Medellín El Tesoro
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"Todo de este hotel estaba perfecto algo muy diferente, disfrutamos demasiado quedarnos aquí"
Lorena 3-night trip
Posted 8 hours ago
Calle Flora Hotel by Jalo
Laureles Selection Suites

Laureles Selection Suites

10/10 Excellent
"Very professional staff, clean humble great restaurant we totally recommend."
Bettina 4-night trip
Posted 10 hours ago
Laureles Selection Suites
Hotel Provenza Garden

Hotel Provenza Garden

10/10 Excellent
"Las habitaciones, cómodas y limpias. La ubicación del hotel es impresionante, super céntrico. El personal, es extraordinariamente amable y servicial. No dudaría en quedarme nuevamente en Hotel Provenza Garden."
CARLOS 7-night trip
Posted 15 hours ago
Hotel Provenza Garden
Hotel Dorado La 70

Hotel Dorado La 70

8/10 Good
"The AC didn’t cool down enough"
Jordi 3-night trip
Posted 1 day ago
Hotel Dorado La 70

More cheap stays in Santa Cruz

Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
$27 nightly
$27 total
Oct 23 - Oct 24
8.4/10 Very Good! (164 reviews)
Hostal Lleras Calle 8 - Hostel
Hotel Ofix - Laureles

Hotel Ofix - Laureles

79-86 Calle 44 Medellín
$32 nightly
$32 total
Sep 28 - Sep 29
Hotel Ofix - Laureles
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
$42 nightly
$42 total
Sep 28 - Sep 29
9.2/10 Wonderful! (96 reviews)
Autenthico Sajonia Hotel Aeropuerto
Viajero Hostel Medellin

Viajero Hostel Medellin

Calle 11A # 43D - 11 Medellín Antioquia
$61 nightly
$61 total
Oct 21 - Oct 22
Viajero Hostel Medellin
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
$63 nightly
$63 total
Sep 24 - Sep 25
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
$91 nightly
$91 total
Oct 19 - Oct 20
9.2/10 Wonderful! (214 reviews)
Masaya Medellin

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $25 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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