
Find hotels in Santa Cruz from $22
- Upfront pricingOur total price for your stay includes taxes and fees
- Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santa Cruz
Pet friendly
Check prices for these dates
Our top choices for Santa Cruz hotels

Hotel Lagoon
Hotel LagoonRionegro
9.2 out of 10, Wonderful, (338 reviews)
$114 nightly
The price is $114
May 19 - May 20

Hotel Santiago de Arma
Hotel Santiago de ArmaRionegro
9.2 out of 10, Wonderful, (951 reviews)
$111 nightly
The price is $111
May 3 - May 4

Soy Local Reserva Sajonia
Soy Local Reserva SajoniaRionegro
8.8 out of 10, Excellent, (89 reviews)
$81 nightly
The price is $81
May 4 - May 5

Isak Hotel & Golf Airport
Isak Hotel & Golf AirportRionegro
9.2 out of 10, Wonderful, (671 reviews)
$78 nightly
The price is $78
May 4 - May 5

Movich Hotel Las Lomas
Movich Hotel Las LomasRionegro
9.0 out of 10, Wonderful, (1,005 reviews)
$147 nightly
The price is $147
May 29 - May 30

Autenthico Sajonia Hotel Aeropuerto
Autenthico Sajonia Hotel AeropuertoRionegro
9.2 out of 10, Wonderful, (77 reviews)
$54 nightly
The price is $54
May 4 - May 5

Travelers Rio Verde Living Suites
Travelers Rio Verde Living SuitesRionegro
8.4 out of 10, Very Good, (473 reviews)
$78 nightly
The price is $78
May 2 - May 3

Medellinn The Blooming Hotel
Medellinn The Blooming HotelEl Poblado
10.0 out of 10, Exceptional, (17 reviews)
$55 nightly
The price is $55
May 12 - May 13

Dann Carlton Medellin Hotel
Dann Carlton Medellin HotelEl Poblado
9.0 out of 10, Wonderful, (1,825 reviews)
$77 nightly
The price is $77
May 3 - May 4

Novotel Medellín El Tesoro
Novotel Medellín El TesoroEl Poblado
9.4 out of 10, Exceptional, (1,456 reviews)
$140 nightly
The price is $140
May 24 - May 25

Fairfield by Marriott Medellin Sabaneta
Fairfield by Marriott Medellin SabanetaSabaneta
9.4 out of 10, Exceptional, (264 reviews)
$80 nightly
The price is $80
May 2 - May 3

Hashtag 98 Hotel By Jalo
Hashtag 98 Hotel By JaloEl Poblado
9.2 out of 10, Wonderful, (1,921 reviews)
$90 nightly
The price is $90
May 27 - May 28

Hotel Park 10
Hotel Park 10El Poblado
9.4 out of 10, Exceptional, (1,404 reviews)
$74 nightly
The price is $74
Apr 29 - Apr 30

Marquee Hotel
Marquee HotelEl Poblado
9.2 out of 10, Wonderful, (197 reviews)
$132 nightly
The price is $132
May 5 - May 6

Hotel Once22
Hotel Once22Sabaneta
9.6 out of 10, Exceptional, (71 reviews)
$45 nightly
The price is $45
Apr 30 - May 1

Hotel Du Parc
Hotel Du ParcEl Poblado
9.4 out of 10, Exceptional, (1,006 reviews)
$135 nightly
The price is $135
Apr 29 - Apr 30

ibis budget Medellín Itagüí Metro
ibis budget Medellín Itagüí MetroItagüí
9.0 out of 10, Wonderful, (420 reviews)
$34 nightly
The price is $34
May 15 - May 16

The Click Clack Hotel Medellin
The Click Clack Hotel MedellinEl Poblado
9.2 out of 10, Wonderful, (1,123 reviews)
$197 nightly
The price is $197
May 25 - May 26

York Medellin, Curio Collection by Hilton
York Medellin, Curio Collection by HiltonEl Poblado
9.6 out of 10, Exceptional, (1,162 reviews)
$171 nightly
The price is $171
May 2 - May 3

Selvario 36 Hotel
Selvario 36 HotelEl Poblado
9.4 out of 10, Exceptional, (703 reviews)
$152 nightly
The price is $152
Apr 29 - Apr 30
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Santa Cruz Hotel Reviews

V Grand Hotel, a member of Radisson Individuals
2/10 Terrible
More cheap stays in Santa Cruz

Hostal Lleras Calle 8 - Hostel
Calle 8 # 37A - 59 Medellín Antioquia
$22 nightly
The price is $22 total per night from Apr 29 to Apr 30
$22 total
Apr 29 - Apr 30
8.4/10 Very Good! (139 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Acevedo Station
- Apartments in Acevedo Station
- Hotels near Aranjuez Park
- Hotels near Castilla
- Hotels near Morro de Moravia
- Hotels near Medellin Botanical Garden
- Hotels near Manrique
- Hotels near University of Antioquia
- Hotels near Hospital Universitario San Vicente de Paul
- Hotels near Hospital Pablo Tobon Uribe
- Hotels near Bello Station
- Hotels near Robledo
- Hotels near Universidad Nacional Sede Medellin
- Bello Hotels
- Hotels near Medellin Cathedral
- Hotels near La Candelaria
- Hotels near Mercado de San Alejo
- Hotels near Arvi Park
- Hotels near Niquia Station
- Hotels near Villa Hermosa
- Hotels near Botero Plaza
- 5 Star Hotels in Bello
- Cabin Rentals in Bello
- Aparthotels in Bello
- Hostels in Bello
- B&B in Bello
- Guest Houses in Bello
- Chalets in Bello
- 3 Star Hotels in Bello
- Hotels near Coltejer Building
- Hotels near Parque Berrio Station
- Hotels near Berrio Park
- Cheap Hotels in La Candelaria
- Hotel Wedding Venues Hotels in La Candelaria
- Luxury Hotels in La Candelaria
- Casino Hotels in La Candelaria
- Apartments in Niquia Station
- B&B in Parque Berrio Station
- Hotels near San Antonio Station
- Hotels near Cisneros Station
- Hotels near San Antonio Park
- Medellin Hotels
- Hotels near Atanasio Giradot Stadium
- Hotels near Estadio
- Medellín Hotels
- Hotels near Estadio Station
- Hotels near Piedras Blancas Ecological Park
- Rv Parks in Cisneros Station
- Apartments in Suramericana Station
- Antioquia Hotels
- Hotels near Antioquia Government Office
- Hotels near Laureles - Estadio
- Hotels near Floresta Station
- Luxury Hotels in Medellín
- Extended Stay Hotels in Medellín
- Melia Hotels in Medellín
- Gay friendly Hotels in Medellín
- Aranjuez Park
- Golf Club Briceno
- Medellin Botanical Garden
- North Park
- Explora Park
- Cementerio de San Pedro
- University of Antioquia
- Hospital Universitario San Vicente de Paul
- Hospital Pablo Tobon Uribe
- Volador's Hill Eco Park
- El Volador Hill
- Visit Bello
- Bello Vacations
- Medellin Cathedral
- Bolivar's Park
- Visit La Candelaria
- Arvi Park
- Mercado de San Alejo
- Botero Plaza
- Antioquia Museum
- Palacio de la Cultura
- Mariposario Selva Viva
- Coltejer Building
- Berrio Park
- Medellin Boston's Park
- La Gorda Sculpture
- Atanasio Giradot Stadium
- Medellín Vacations









































































