Top 10 Hotels in Santa Cruz () 2026 - Competitive Prices

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Our top choices for Santa Cruz hotels

A buffet with various fruits, vegetables, and beverages.

A bar area with a curved counter, shelves with bottles, and hanging wine glasses.

A person using a laptop in a hotel room with a bed, a chair, and a small table.

A modern outdoor seating area with a mix of tables and sofas, surrounded by lush green plants and a metal fence.

1. ibis Medellin

El Poblado

Yuliana

$55 nightly

$55 total

Nov 1 - Nov 2

A swimming pool with tiled edges, surrounded by lounge chairs and palm trees.

A bedroom with a wooden ceiling, a brick wall, a bed with pillows, a nightstand, and a chair.

A traditional wooden building with a sloped roof and a balcony.

A spacious indoor venue with high ceilings and natural light, featuring wooden tables and chairs, and various floral arrangements.

2. Autenthico Sajonia Hotel Aeropuerto

Rionegro

Mabel Angela Frias

$37 nightly

$37 total

Oct 19 - Oct 20

A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.

A multi-story building with a modern architectural design, featuring large windows and a brick facade.

A hotel room with a bed, a small table with chairs, a coffee maker, and a view of the city through the window.

3. Urbit Social Lofts

Laureles

Richard

$49 nightly

$49 total

Oct 19 - Oct 20

A bedroom with a large bed, a chair, and a view through a glass door.

A modern bedroom with a large bed, wooden headboard, bedside tables, and a view of greenery through a window.

A modern glass structure with a roof, surrounded by a well-maintained lawn and trees.

4. Isak Hotel & Golf Airport

Rionegro

Cristina

$81 nightly

$81 total

Oct 23 - Oct 24

A hotel sign with a sun emblem, a modern glass building, and flags.

A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.

A modern lobby with green sofas, a white coffee table, and a large potted plant.

A neatly arranged bedroom with a bed, bedside table, and a desk with a chair.

5. La Quinta by Wyndham Medellin

San Diego

Domingo

$93 nightly

$93 total

Oct 16 - Oct 17

A plate with a breaded item, two dipping sauces, and a small bowl of oil.

An outdoor patio area with tables and chairs, a large canopy, and a brick wall.

A modern hotel room with a large bed, bedside tables, a sofa, and a view of the city through the window.

A hotel lobby with a reception desk, a large potted plant, a check-in counter, and a seating area.

6. Hotel Dann Carlton Belfort Medellin

El Poblado

Christian Alvarez

$86 nightly

$86 total

Oct 20 - Oct 21

A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.

A modern lobby with glass walls, a tiled floor, and a potted plant.

A modern reception area with a black counter, a digital display, and a wall decorated with food and drink illustrations.

A modern interior with a blue sofa, a hanging chair, a vending machine, and a refrigerator stocked with beverages.

7. ibis budget Medellín Itagüí Metro

Itagüí

Jose

$45 nightly

$45 total

Oct 30 - Oct 31

A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.

A bar area with a green wall, bar stools, and a counter with a bartender.

A spacious indoor dining area with multiple tables and chairs, large windows offering city views, and visible air ducts on the ceiling.

A modern hotel room with a large bed, a cityscape mural on the wall, a wooden headboard, and a walk-in closet.

8. Hotel Dorado La 70

Laureles

Gregson

$81 nightly

$81 total

Nov 13 - Nov 14

An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.

A modern kitchen with a central island, bar stools, and a hanging plant.

A modern living area with a sofa, ottomans, and a dining area with chairs and a table.

A modern hotel entrance with a prominent sign reading "Fairfield by Marriott" and a staircase leading to the lobby.

9. Fairfield by Marriott Medellin Sabaneta

Sabaneta

Michael

$81 nightly

$81 total

Nov 1 - Nov 2

A modern bar with a long counter, shelves with decorative items, and a coffee machine.

A restaurant with multiple tables and chairs, large windows offering a view of mountains and cityscape, and indoor plants.

A swimming pool with a glass barrier, surrounded by high-rise buildings and greenery.

A city view from a high-rise room with a chair and a table.

10. Novotel Medellín El Tesoro

El Poblado

Oscar

$139 nightly

$139 total

Nov 6 - Nov 7

A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.

A modern hotel room with a large bed, a sitting area with a table and chairs, a bathtub, and a balcony with a view of the city.

A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.

A multi-story hotel with a prominent 'EUTOPIO' sign, featuring a modern architectural design with a mix of brick and glass facades, and balconies with greenery.

11. Eutopiq Hotel

Laureles

Ramiro

$77 nightly

$77 total

Oct 14 - Oct 15

A room with large windows, a patterned carpet, and a table with chairs.

A modern hotel room with a large bed, a desk, a chair, a television, and a window with a view of trees and buildings.

A conference room with a long table, black chairs, a white air conditioning unit, and a glass partition with a number sign.

A gym with two people using stationary bikes, a treadmill, and a rowing machine.

12. Hotel BH El Poblado

El Poblado

Anthony

$84 nightly

$84 total

Nov 10 - Nov 11

A modern interior with a circular window, a seating area with a cushioned bench, and a small table.

A multi-story building with a brick facade, a restaurant named 'BACU' on the ground floor, and a sign for 'Planetaws' to the left.

A modern bathroom with a round mirror, a sink, a toilet, and a glass-enclosed shower.

A hotel room with a bed, a desk with a chair, a television, and a window with curtains.

13. Urbit Garden Hotel

Laureles

Elio Rafael

$57 nightly

$57 total

Oct 16 - Oct 17

A modern kitchen with a central island, bar area, and seating.

A modern living room with a sofa, a chair, a coffee table, and a potted plant.

A modern building with a prominent 'Loma' sign, a staircase leading to the entrance, and lush greenery around the base.

A modern living room with a sectional sofa, a neon 'RECORDS' sign, a shelving unit with shoes, and a hanging light fixture.

14. Loma, Medellin, a Tribute Portfolio Hotel

El Poblado

Solymar

$92 nightly

$92 total

Oct 23 - Oct 24

A modern reception area with a glass door entrance, a reception desk, and seating arrangements.

A gym with exercise equipment, a punching bag, and a view of the city through large windows.

A modern interior with multiple ceiling lights, large windows, and a visible air conditioning unit.

A hotel room with a bed, a tray with a bottle and glasses, a red pillow, and a view of the outside through sheer curtains.

15. Arame Hotel

Envigado

$71 nightly

$71 total

Nov 13 - Nov 14

A woman in a black swimsuit sitting in a hot tub with a cityscape view through a glass railing.

A modern hotel room with a bed, a desk, a TV, and a balcony with a view.

A modern high-rise building with multiple balconies, surrounded by greenery and other residential buildings.

A modern interior with a sofa, two armchairs, a coffee table, and a large potted plant.

16. Hotel Living 35 Suites by Growing Group

La América

Margarita

$47 nightly

$47 total

Oct 14 - Oct 15

A modern building entrance with glass doors, a wooden ceiling, and potted plants.

A building with a wooden lattice facade and a sign reading 'PERGAMINO.'

A gym with wooden floors, weight racks, and exercise equipment.

A modern hotel room with a large bed, bedside tables, a bench, a potted plant, and a sliding door closet.

17. The Cut Hotel

El Poblado

Arturo

$55 nightly

$55 total

Nov 2 - Nov 3

A modern bedroom with a large bed, bedside table, and a view of trees through a window.

A modern living space with a central island, a dining area, and a kitchen.

A spa area with a hot tub, seating, and plants.

A modern bathroom with a white toilet, a large sink, and a mirror above it. There are two bottles on the sink counter.

18. Soy Local Reserva Sajonia

Rionegro

Antonio

$71 nightly

$71 total

Oct 14 - Oct 15

A hotel entrance with a modern design, featuring a staircase leading to the lobby, a chandelier, and a sign indicating the hotel's name.

A modern hotel room with a large bed, a flat-screen TV, a dark-colored sofa, and a large window with curtains.

A modern living room with a flat-screen TV, a sofa, a coffee table, and a small cabinet.

A gym with a treadmill, a small table with a bottle and a towel, and a spa area with candles and towels.

19. Hotel Egina Medellín

Laureles - Estadio

David

$66 nightly

$66 total

Nov 12 - Nov 13

A reflective pool with a cityscape and mountains in the background.

A modern hotel room with a large bed, a wooden desk, a black curtain, a brick accent wall, and a balcony with plants.

A library with bookshelves, a ladder, a round table, and a potted plant.

A modern bedroom with a large bed, a bench, and a brick wall.

20. Los Patios Cool Living

Laureles

Emilio

$64 nightly

$64 total

Oct 14 - Oct 15

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Top Santa Cruz Hotel Reviews

Dann Carlton Medellin Hotel

10/10 Excellent

"Todo. Excelente"

Calle Flora Hotel by Jalo

8/10 Good

"Los cuartos son algo pequeños al menos el que yo escogí tal vez por que era la habitación más barata pero no pude descansar bien había mucha bulla y no sola de fuera si no también del cuarto de alado mío que estaban justo haciendo arreglos"

The Click Clack Hotel Medellin

10/10 Excellent

"Worth every penny!"

Urbit Social Lofts

8/10 Good

"The location was amazing, room was nice for a quick trip. The rooftop bar was such a vibe too. Only thing is that because this hotel is right on the main street in Laureles, the room was quite noisy. I had to get ear plugs to sleep at night. Tried asking to move to another room on a higher floor but the hotel was sold out."

The Cut Hotel

10/10 Excellent

"Muy chevere y cool el hotel!"

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent

"Excelente lugar"

Heiss Hotel By Jalo

8/10 Good

"What I like the most about the Hotel was how they treated us, all the Security Guards were very nice and polite, the girls in the Restaurant, we loved the pizza, Santiago the guy in the bar, the server also incredible people. Save place and area . Thanks for everything"

Novotel Medellín El Tesoro

10/10 Excellent

"Clean and comfortable rooms, friendly staff, good breakfast, and an excellent location. Highly recommended!"

Moa Select

10/10 Excellent

"👍"

Frequently asked questions

What is the best area to stay in Santa Cruz?

The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.

When is the best time to go to Santa Cruz?

The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.

How much is the nightly rate at a Santa Cruz hotel?

Prices for hotels in Santa Cruz often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Find hotels in Santa Cruz

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Cruz hotels

1. ibis Medellin

2. Autenthico Sajonia Hotel Aeropuerto

3. Urbit Social Lofts

4. Isak Hotel & Golf Airport

5. La Quinta by Wyndham Medellin

6. Hotel Dann Carlton Belfort Medellin

7. ibis budget Medellín Itagüí Metro

8. Hotel Dorado La 70

9. Fairfield by Marriott Medellin Sabaneta

10. Novotel Medellín El Tesoro

11. Eutopiq Hotel

12. Hotel BH El Poblado

13. Urbit Garden Hotel

14. Loma, Medellin, a Tribute Portfolio Hotel

15. Arame Hotel

16. Hotel Living 35 Suites by Growing Group

17. The Cut Hotel

18. Soy Local Reserva Sajonia

19. Hotel Egina Medellín

20. Los Patios Cool Living

Top Santa Cruz Hotel Reviews

Dann Carlton Medellin Hotel

Calle Flora Hotel by Jalo

The Click Clack Hotel Medellin

Urbit Social Lofts

The Cut Hotel

V Grand Hotel, a member of Radisson Individuals

Heiss Hotel By Jalo

Novotel Medellín El Tesoro

Moa Select

Frequently asked questions

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