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Our top choices for Santa Cruz hotels

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (338 reviews)
"Great breakfast"
United States
Max
$114 nightly
The price is $114
May 19 - May 20
Hotel Lagoon

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (951 reviews)
"Great hotel "
United States
Mario
$111 nightly
The price is $111
May 3 - May 4
Hotel Santiago de Arma

Soy Local Reserva Sajonia

Soy Local Reserva Sajonia
2.5 star property
Rionegro
8.8 out of 10, Excellent, (89 reviews)
"Super nice place to stay near the Airport. Friendly staff and very accommodating. "
United States
Christian
$81 nightly
The price is $81
May 4 - May 5
Soy Local Reserva Sajonia

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (671 reviews)
"We have a great stay"
United States
Shwon
$78 nightly
The price is $78
May 4 - May 5
Isak Hotel & Golf Airport

Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
Rionegro
9.0 out of 10, Wonderful, (1,005 reviews)
"Best hotel in Rionegro 10/10"
United States
ROBERTO
$147 nightly
The price is $147
May 29 - May 30
Movich Hotel Las Lomas

Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
2.0 star property
Rionegro
9.2 out of 10, Wonderful, (77 reviews)
"Staff were so wonderful very helpful "
United States
Kevin
$54 nightly
The price is $54
May 4 - May 5
Autenthico Sajonia Hotel Aeropuerto

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
$78 nightly
The price is $78
May 2 - May 3
Travelers Rio Verde Living Suites

Medellinn The Blooming Hotel

Medellinn The Blooming Hotel
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (17 reviews)
"Very new and very clean. The staff is always welcoming and helpful. Beatiful decor and just what we needed for our short stay. "
United States
Rosanna
$55 nightly
The price is $55
May 12 - May 13
Medellinn The Blooming Hotel

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
El Poblado
9.0 out of 10, Wonderful, (1,825 reviews)
"Very well located, staff nice"
United States
yazmarys
$77 nightly
The price is $77
May 3 - May 4
Dann Carlton Medellin Hotel

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,456 reviews)
"Great place!"
United States
Sebastian
$140 nightly
The price is $140
May 24 - May 25
Novotel Medellín El Tesoro

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (264 reviews)
"Nice staff, good food, easy onsite parking and great location "
United States
Lynn
$80 nightly
The price is $80
May 2 - May 3
Fairfield by Marriott Medellin Sabaneta

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,921 reviews)
"Nice hotel at a nice spot."
Canada
Hamidreza
$90 nightly
The price is $90
May 27 - May 28
Hashtag 98 Hotel By Jalo

Hotel Park 10

Hotel Park 10
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (1,404 reviews)
"Great place to stay!"
United States
Brian
$74 nightly
The price is $74
Apr 29 - Apr 30
Hotel Park 10

Marquee Hotel

Marquee Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (197 reviews)
"Great location and staff. I would stay here again. "
United States
James
$132 nightly
The price is $132
May 5 - May 6
Marquee Hotel

Hotel Once22

Hotel Once22
3.0 star property
Sabaneta
9.6 out of 10, Exceptional, (71 reviews)
"ROOM CLEAN, BREAKFAST FRESH, STAFF REMARKABLE, AND SHOPS/RESTAURANTS/BARS RIGHT OUTSIDE."
United States
Alfonso
$45 nightly
The price is $45
Apr 30 - May 1
Hotel Once22

Hotel Du Parc

Hotel Du Parc
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,006 reviews)
"Excellent hotel "
United States
Jenny
$135 nightly
The price is $135
Apr 29 - Apr 30
Hotel Du Parc

ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
3.0 star property
Itagüí
9.0 out of 10, Wonderful, (420 reviews)
"Love staying in this hotel! Very clean, within budget, next to the train station which is the best part of all. Very recommended"
United States
Fernando
$34 nightly
The price is $34
May 15 - May 16
ibis budget Medellín Itagüí Metro

The Click Clack Hotel Medellin

The Click Clack Hotel Medellin
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,123 reviews)
"Great ambience, delicious breakfast, and great staff!"
United States
Todd
$197 nightly
The price is $197
May 25 - May 26
The Click Clack Hotel Medellin

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1,162 reviews)
"Excellent hotel. "
United States
Jose Luis
$171 nightly
The price is $171
May 2 - May 3
York Medellin, Curio Collection by Hilton

Selvario 36 Hotel

Selvario 36 Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (703 reviews)
"Great location, excellent food and drinks. "
United States
Katelyn
$152 nightly
The price is $152
Apr 29 - Apr 30
Selvario 36 Hotel
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Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.

El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.

Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.

For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.

During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.

Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How can I save on a Santa Cruz hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Cruz hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $22 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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