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Oct 17 - Oct 18
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Our top choices for Santa Cruz hotels

A swimming pool with tiled edges, surrounded by lounge chairs and palm trees.
A traditional wooden building with a sloped roof and a balcony.
A bedroom with a wooden ceiling, a brick wall, a bed with pillows, a nightstand, and a chair.
A spacious indoor venue with high ceilings and natural light, featuring wooden tables and chairs, and various floral arrangements.

1. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
Rionegro
United States
Mabel Angela Frias
$29 nightly
$29 total
Oct 26 - Oct 27
Autenthico Sajonia Hotel Aeropuerto
A buffet with various fruits, vegetables, and beverages.
A bar area with a curved counter, shelves with bottles, and hanging wine glasses.
A person using a laptop in a hotel room with a bed, a chair, and a small table.
A modern outdoor seating area with a mix of tables and sofas, surrounded by lush green plants and a metal fence.

2. ibis Medellin

ibis Medellin
El Poblado
United States
Yuliana
$55 nightly
$55 total
Oct 18 - Oct 19
ibis Medellin
A rooftop pool area with a breakfast setup, including plates, cups, and juice.
A multi-story building with a brick facade, surrounded by lush greenery and other high-rise buildings.
An outdoor patio area with tables and chairs, a large canopy, and a brick wall.
A hotel with a swimming pool, brick exterior, and surrounding greenery.

3. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
El Poblado
United States
Christian Alvarez
$83 nightly
$83 total
Oct 18 - Oct 19
Hotel Dann Carlton Belfort Medellin
A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.
A reception area with a brick wall, wooden tables, wicker pendant lights, and a reception desk.
A hotel room with a bed, a small table with chairs, a coffee maker, and a view of the city through the window.
A multi-story building with a modern architectural design, featuring large windows and a brick facade.

4. Urbit Social Lofts

Urbit Social Lofts
Laureles
United States
Marloane
$50 nightly
$50 total
Oct 25 - Oct 26
Urbit Social Lofts
A bedroom with a large bed, a chair, and a view through a glass door.
A reception desk with a wooden finish, a logo, and a view of greenery outside.
A modern bedroom with a large bed, wooden headboard, bedside tables, and a view of greenery through a window.
A modern glass structure with a roof, surrounded by a well-maintained lawn and trees.

5. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
Rionegro
United States
Juwan
$80 nightly
$80 total
Oct 23 - Oct 24
Isak Hotel & Golf Airport
A modern building entrance with glass doors, a wooden ceiling, and potted plants.
A gym with wooden floors, weight racks, and exercise equipment.
An indoor seating area with tables and chairs, a large sign reading 'PERGAMINO,' and a wooden wall design.
A building with a wooden lattice facade and a sign reading 'PERGAMINO.'

6. The Cut Hotel

The Cut Hotel
El Poblado
United States
Arturo
$48 nightly
$48 total
Oct 19 - Oct 20
The Cut Hotel
A modern bar with a long counter, shelves with decorative items, and a coffee machine.
A swimming pool with a glass barrier, surrounded by high-rise buildings and greenery.
A restaurant with multiple tables and chairs, large windows offering a view of mountains and cityscape, and indoor plants.
A modern hotel lobby with a reception desk, seating area, and large windows.

7. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
El Poblado
United States
Haydee
$146 nightly
$146 total
Nov 7 - Nov 8
Novotel Medellín El Tesoro
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.
A casino with multiple slot machines and chairs arranged in rows.
A bar area with a green wall, bar stools, and a counter with a bartender.
A modern hotel room with a large bed, a cityscape mural on the wall, a wooden headboard, and a walk-in closet.

8. Hotel Dorado La 70

Hotel Dorado La 70
Laureles
United States
Gregson
$91 nightly
$91 total
Oct 20 - Oct 21
Hotel Dorado La 70
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.
A modern kitchen with a central island, bar stools, and a hanging plant.
A modern kitchen area with wooden cabinets, a countertop, and a fruit bowl.
A modern living area with a sofa, ottomans, and a dining area with chairs and a table.

9. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
Sabaneta
United States
Michael
$81 nightly
$81 total
Nov 1 - Nov 2
Fairfield by Marriott Medellin Sabaneta
A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.
A modern interior with a blue sofa, a hanging chair, a vending machine, and a refrigerator stocked with beverages.
A brick building with a sign reading "ibis budget."
A modern lobby with glass walls, a tiled floor, and a potted plant.

10. ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
Itagüí
United States
Jose
$37 nightly
$37 total
Oct 24 - Oct 25
ibis budget Medellín Itagüí Metro
A hotel sign with a sun emblem, a modern glass building, and flags.
A rooftop terrace with lounge chairs and a large umbrella, overlooking a cityscape at dusk.
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.
A modern lobby with green sofas, a white coffee table, and a large potted plant.

11. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
San Diego
United States
Domingo
$84 nightly
$84 total
Oct 19 - Oct 20
La Quinta by Wyndham Medellin
A reflective pool with a cityscape and mountains in the background.
A modern lounge area with a sofa, chairs, and a coffee table.
A modern bedroom with a large bed, a bench, and a brick wall.
A modern hotel room with a large bed, a wooden desk, a black curtain, a brick accent wall, and a balcony with plants.

12. Los Patios Cool Living

Los Patios Cool Living
Laureles
United States
Emilio
$65 nightly
$65 total
Oct 21 - Oct 22
Los Patios Cool Living
A tall building with a modern design, featuring large windows and a sign that reads "SPRING SELECT EST 2025".
A woman standing by a spa tub with a window and plants in the background.
A bar area with shelves of wine bottles and glasses, decorated with green foliage.
A restaurant with booths, tables, and chairs, featuring a modern design with plants and pendant lighting.

13. Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
Laureles
Canada
Neil
$40 nightly
$40 total
Oct 26 - Oct 27
Hotel Ryo 74B Suites by Growing Group
A modern interior with a circular window, a seating area with a cushioned bench, and a small table.
A hotel room with a bed, a desk with a chair, a television, and a window with curtains.
A multi-story building with a brick facade, a restaurant named 'BACU' on the ground floor, and a sign for 'Planetaws' to the left.
A compact room with a desk, chair, coffee maker, and a trash bin.

14. Urbit Garden Hotel

Urbit Garden Hotel
Laureles
United States
Elio Rafael
$69 nightly
$69 total
Oct 21 - Oct 22
Urbit Garden Hotel
A modern hotel room with a large bed, a wooden headboard, a bedside table with a lamp, and a tray with breakfast items.
A modern reception area with a wooden reception desk, large potted plants, and a view of the outdoors through large windows.
A dining table with a plate of food, wine glasses, and a bottle of wine.
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a modern building.

15. Hotel Lagoon

Hotel Lagoon
Rionegro
United States
Vanessa
$114 nightly
$114 total
Nov 17 - Nov 18
Hotel Lagoon
A swimming pool with lounge chairs and umbrellas, surrounded by modern buildings.
A hotel lobby with a reception desk, a chandelier, a piano, and a large mirror.
A modern building with a glass facade and a hot tub in front.
A modern dining area with a glass-top table, surrounded by chairs, and a chandelier.

16. Hotel San Fernando Plaza

Hotel San Fernando Plaza
El Poblado
United States
Julio
$78 nightly
$78 total
Oct 18 - Oct 19
Hotel San Fernando Plaza
A modern reception area with a glass door entrance, a reception desk, and seating arrangements.
A modern living room with a round wooden coffee table, white chairs, a sofa, and a potted plant.
A gym with exercise equipment, a punching bag, and a view of the city through large windows.
A modern building with a prominent corner design, large windows, and a patterned facade.

17. Arame Hotel

Arame Hotel
Envigado
United States
David
$69 nightly
$69 total
Oct 25 - Oct 26
Arame Hotel
A modern bedroom with a large bed, bedside table, and a view of trees through a window.
A modern bathroom with a white toilet, a large sink, and a mirror above it. There are two bottles on the sink counter.
A modern living space with a central island, a dining area, and a kitchen.
A spa area with a hot tub, seating, and plants.

18. Soy Local Reserva Sajonia

Soy Local Reserva Sajonia
Rionegro
United States
Antonio
$68 nightly
$68 total
Oct 20 - Oct 21
Soy Local Reserva Sajonia
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.
Gift shop
A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.
A modern hotel room with a large bed, a sitting area with a table and chairs, a bathtub, and a balcony with a view of the city.

19. Eutopiq Hotel

Eutopiq Hotel
Laureles
United States
Ramiro
$77 nightly
$77 total
Oct 25 - Oct 26
Eutopiq Hotel
A multi-level outdoor pool area with tiered wooden structures, lounge chairs, and umbrellas.
A modern building with a unique circular wooden balcony design, surrounded by greenery and a clear sky.
A modern reception area with a green sofa, a reception desk, and a large, circular ceiling light fixture.
A hotel room with a wooden vanity, a bed, a large window with a mountain view, and a flat-screen TV mounted on the wall.

20. Heiss Hotel By Jalo

Heiss Hotel By Jalo
El Poblado
United States
Mario
$69 nightly
$69 total
Oct 18 - Oct 19
Heiss Hotel By Jalo
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Top Santa Cruz Hotel Reviews

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

10/10 Excellent
"Per previous rating; customer service was excellent; the staff met my various request promptly; the service transportation that was used and the personnel they used was professional and excelled my expectations at all time, as well as the hotel . I will recommend Novotel to all my friends . As always Thank you to the Novotel Team! Until next time ."
Martha E 11-night trip
Posted 1 hour ago
Novotel Medellín El Tesoro
La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin

10/10 Excellent
"Muy buena experiencia."
Milton 5-night trip
Posted 1 hour ago
La Quinta by Wyndham Medellin
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"The staff was nice and very helpful when asked for recommendations. Definitely will be staying here again."
Christian 3-night trip
Posted 9 hours ago
Calle Flora Hotel by Jalo
Heiss Hotel By Jalo

Heiss Hotel By Jalo

10/10 Excellent
"Excellent property with amazing staff and great food! Very central to several restaurants and great attractions."
Jamaro 8-night trip
Posted 10 hours ago
Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

10/10 Excellent
"Staff and everyone was very welcoming and attentive when I needed them. Highly recommended the stay if you’re looking to be close to all the fun on Calle 70. The Casino next door is a nice touch for when you are looking for something to pass the time. The Bar on the roof is a beautiful touch as well as the gym. Everything is also within walking distance so no need to travel far unless you’re leaving town for the day. Will love to stay here again soon!"
Jose 10-night trip
Posted 11 hours ago
Hotel Dorado La 70
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"Muy bonito hotel , moderno"
Gloria I 4-night trip
Posted 13 hours ago
The Click Clack Hotel Medellin
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Staff was very friendly and professional. Continental breakfast which is included in our stay was excellent."
Noe Denizart 6-night trip
Posted 20 hours ago
Dann Carlton Medellin Hotel
Hotel BH El Poblado

Hotel BH El Poblado

8/10 Good
"Friendly staff and clean quiet room. The rooms do not have a thick certain to block the light completely so if you are sensitive it can be an issue. Breakfast was good."
Payam 2-night trip
Posted 20 hours ago
Hotel BH El Poblado
Firenze Lofts

Firenze Lofts

10/10 Excellent
"Great place !!!"
Ricky 4-night trip
Posted 20 hours ago
Firenze Lofts

More cheap stays in Santa Cruz

Hotel Casa Malibú

Hotel Casa Malibú

Calle 32F 66 c 57 Medellín Medellin
$23 nightly
$23 total
Oct 22 - Oct 23
4.8/10 (3 reviews)
Hotel Casa Malibú
Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
$28 nightly
$28 total
Oct 20 - Oct 21
8.4/10 Very Good! (165 reviews)
Hostal Lleras Calle 8 - Hostel
Hotel Ofix - Laureles

Hotel Ofix - Laureles

79-86 Calle 44 Medellín
$29 nightly
$29 total
Nov 16 - Nov 17
Hotel Ofix - Laureles
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
$29 nightly
$29 total
Oct 26 - Oct 27
Autenthico Sajonia Hotel Aeropuerto
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
$59 nightly
$59 total
Nov 17 - Nov 18
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
$77 nightly
$77 total
Oct 20 - Oct 21
Masaya Medellin

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $23 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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