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Our top choices for Santa Cruz hotels

A buffet with various fruits, vegetables, and beverages.
A modern outdoor seating area with a mix of tables and sofas, surrounded by lush green plants and a metal fence.
Exterior
A bar area with a curved counter, shelves with bottles, and hanging wine glasses.

1. ibis Medellin

ibis Medellin
El Poblado
United States
Yuliana
$57 nightly
$57 total
Oct 24 - Oct 25
ibis Medellin
A swimming pool with tiled edges, surrounded by lounge chairs and palm trees.
A spacious indoor venue with high ceilings and natural light, featuring wooden tables and chairs, and various floral arrangements.
A bedroom with a wooden ceiling, a brick wall, a bed with pillows, a nightstand, and a chair.
A cobblestone path leading to a house with a tiled roof, surrounded by lush greenery and vibrant pink bougainvillea flowers.

2. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
Rionegro
United States
Mabel Angela Frias
$34 nightly
$34 total
Oct 19 - Oct 20
Autenthico Sajonia Hotel Aeropuerto
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.
A modern kitchen with a central island, bar stools, and a hanging plant.
A modern hotel entrance with a prominent sign reading "Fairfield by Marriott" and a staircase leading to the lobby.
A modern kitchen area with wooden cabinets, a countertop, and a fruit bowl.

3. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
Sabaneta
United States
Michael
$84 nightly
$84 total
Oct 12 - Oct 13
Fairfield by Marriott Medellin Sabaneta
A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.
A reception area with a brick wall, wooden tables, wicker pendant lights, and a reception desk.
A hotel room with a bed, a small table with chairs, a coffee maker, and a view of the city through the window.
A multi-story building with a modern architectural design, featuring large windows and a brick facade.

4. Urbit Social Lofts

Urbit Social Lofts
Laureles
United States
Richard
$55 nightly
$55 total
Oct 8 - Oct 9
Urbit Social Lofts
A hotel sign with a sun emblem, a modern glass building, and flags.
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.
A rooftop terrace with lounge chairs and a large umbrella, overlooking a cityscape at dusk.
A neatly arranged bedroom with a bed, bedside table, and a desk with a chair.

5. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
San Diego
United States
Domingo
$93 nightly
$93 total
Oct 9 - Oct 10
La Quinta by Wyndham Medellin
A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.
A modern reception area with a black counter, a digital display, and a wall decorated with food and drink illustrations.
A brick building with a sign reading "ibis budget."
A modern interior with a blue sofa, a hanging chair, a vending machine, and a refrigerator stocked with beverages.

6. ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
Itagüí
United States
Maria
$44 nightly
$44 total
Oct 24 - Oct 25
ibis budget Medellín Itagüí Metro
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.
A modern hotel room with a large bed, a cityscape mural on the wall, a wooden headboard, and a walk-in closet.
A casino with multiple slot machines and chairs arranged in rows.
A spacious indoor dining area with multiple tables and chairs, large windows offering city views, and visible air ducts on the ceiling.

7. Hotel Dorado La 70

Hotel Dorado La 70
Laureles
United States
Gregson
$87 nightly
$87 total
Nov 6 - Nov 7
Hotel Dorado La 70
A bedroom with a large bed, a chair, and a view through a glass door.
A modern glass structure with a roof, surrounded by a well-maintained lawn and trees.
A modern bedroom with a large bed, wooden headboard, bedside tables, and a view of greenery through a window.
A garden pathway with various plants and a palm tree.

8. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
Rionegro
Australia
Cristina
$90 nightly
$90 total
Oct 22 - Oct 23
Isak Hotel & Golf Airport
A room with large windows, a patterned carpet, and a table with chairs.
A modern hotel room with a large bed, a desk, a chair, a television, and a window with a view of trees and buildings.
A modern office space with large windows, a conference table, and a view of the cityscape.
A gym with two people using stationary bikes, a treadmill, and a rowing machine.

9. Hotel BH El Poblado

Hotel BH El Poblado
El Poblado
United States
Maria D Batista
$86 nightly
$86 total
Nov 7 - Nov 8
Hotel BH El Poblado
A hotel room with a bed, a TV, a desk, and a window with curtains.
An indoor seating area with tables and chairs, a large sign reading 'PERGAMINO,' and a wooden wall design.
A gym with wooden floors, weight racks, and exercise equipment.
A building with a wooden lattice facade and a sign reading 'PERGAMINO.'

10. The Cut Hotel

The Cut Hotel
El Poblado
United States
Arturo
$50 nightly
$50 total
Oct 13 - Oct 14
The Cut Hotel
A modern reception area with a glass door entrance, a reception desk, and seating arrangements.
A gym with exercise equipment, a punching bag, and a view of the city through large windows.
A hotel room with a bed, a tray with a bottle and glasses, a red pillow, and a view of the outside through sheer curtains.
A modern living room with a round wooden coffee table, white chairs, a sofa, and a potted plant.

11. Arame Hotel

Arame Hotel
Envigado
United States
David
$75 nightly
$75 total
Nov 7 - Nov 8
Arame Hotel
A modern bar with a long counter, shelves with decorative items, and a coffee machine.
A modern hotel lobby with a reception desk, seating area, and large windows.
A city view from a high-rise room with a chair and a table.
A restaurant with multiple tables and chairs, large windows offering a view of mountains and cityscape, and indoor plants.

12. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
El Poblado
United States
Oscar
$140 nightly
$140 total
Nov 2 - Nov 3
Novotel Medellín El Tesoro
A rooftop pool area with a breakfast setup, including plates, cups, and juice.
A multi-story building with a brick facade, surrounded by lush greenery and other high-rise buildings.
A modern hotel room with a large bed, bedside tables, a sofa, and a view of the city through the window.
A hotel lobby with a reception desk, a large potted plant, a check-in counter, and a seating area.

13. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
El Poblado
United States
Christian Alvarez
$86 nightly
$86 total
Oct 18 - Oct 19
Hotel Dann Carlton Belfort Medellin
A modern hotel room with a large bed, bedside table with a lamp, a desk with a chair, and a potted plant.
A reception area with a wooden slatted wall, a marble reception desk, and a ceiling with exposed beams and lighting.
A building facade with a large 'nnoa' sign, a window with plants, and a metal utility box on the ground.
A hallway with wooden flooring, a potted plant, and a wall-mounted artwork of leaves.

14. Moa Select

Moa Select
Laureles
United Kingdom
Suheil
$47 nightly
$47 total
Oct 13 - Oct 14
Moa Select
A multi-level outdoor pool area with tiered wooden structures, lounge chairs, and umbrellas.
A modern building with a unique circular wooden balcony design, surrounded by greenery and a clear sky.
A hotel room with a large bed, a wooden headboard, a bedside table, a mirror, and a view of the cityscape.
A modern reception area with a green sofa, a reception desk, and a large, circular ceiling light fixture.

15. Heiss Hotel By Jalo

Heiss Hotel By Jalo
El Poblado
United States
Marcus E
$63 nightly
$63 total
Oct 27 - Oct 28
Heiss Hotel By Jalo
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.
Gift shop
A multi-story hotel with a prominent 'EUTOPIO' sign, featuring a modern architectural design with a mix of brick and glass facades, and balconies with greenery.
A modern hotel room with a large bed, a sitting area with a table and chairs, a large window with a view of buildings, and a hot tub.

16. Eutopiq Hotel

Eutopiq Hotel
Laureles
United States
Luis Alfonso
$64 nightly
$64 total
Oct 14 - Oct 15
Eutopiq Hotel
A row of modern, glass-roofed buildings with a garden in front featuring various colorful flowers.
A small, single-story building with a sloped roof, numbered 1 and 2, indicating separate units. A concrete staircase leads to a door with a glass panel, revealing a bed and a wall-mounted light fixture.
A modern room with two beds, a large window with curtains, and artwork on the wall.
A room with two beds, a table, and a chair. There is a window with curtains, and a view of greenery outside.

17. NEW STAR CENTER

NEW STAR CENTER
Rionegro
United States
Julienne
$61 nightly
$61 total
Oct 8 - Oct 9
NEW STAR CENTER
A woman in a black swimsuit sitting in a hot tub with a cityscape view through a glass railing.
A modern interior with a sofa, two armchairs, a coffee table, and a large potted plant.
A modern high-rise building with multiple balconies, surrounded by greenery and other residential buildings.
An indoor cafe with brick walls, tables, chairs, and hanging plants.

18. Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group
La América
United States
Margarita
$53 nightly
$53 total
Oct 25 - Oct 26
Hotel Living 35 Suites by Growing Group
A reflective pool with a cityscape and mountains in the background.
A library with bookshelves, a ladder, a round table, and a potted plant.
A modern lounge area with a sofa, chairs, and a coffee table.
A modern bedroom with a large bed, a bench, and a brick wall.

19. Los Patios Cool Living

Los Patios Cool Living
Laureles
United States
Emilio
$66 nightly
$66 total
Oct 12 - Oct 13
Los Patios Cool Living
A modern outdoor pool area with a wooden deck, lounge chairs, and a table with umbrellas.
A modern meeting room with a wooden table, black chairs, and a potted plant.
A bar area with stools, shelves with bottles, and a counter.
A modern hotel lobby with a long reception desk, seating area, and a large window.

20. Movich Hotel Las Lomas

Movich Hotel Las Lomas
Rionegro
United States
Anuradha
$157 nightly
$157 total
Nov 7 - Nov 8
Movich Hotel Las Lomas
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Top Santa Cruz Hotel Reviews

Hotel BH El Poblado

Hotel BH El Poblado

10/10 Excellent
"Excelente servicio, limpieza y cerca de los principales comercios"
Daniel Rodriguez 4-night trip
Posted 1 hour ago
Hotel BH El Poblado
Heiss Hotel By Jalo

Heiss Hotel By Jalo

10/10 Excellent
"Good"
Kaevoree 4-night trip
Posted 2 hours ago
Heiss Hotel By Jalo
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"Exceeded all our expectations, Lovely hotel Lovely staff! Everyone were amazing. If we had any questions or problems they were handled immediately. Felt secure and very safe with this hotel. I would love to visit Medellin again I would not stay anywhere else but Click Clack hotel. We have traveled a lot of places I can honestly say this was one of if not the best hotel experience Ive had. Thank you!"
Natasha 4-night trip
Posted 4 hours ago
The Click Clack Hotel Medellin
Urbit Social Lofts

Urbit Social Lofts

10/10 Excellent
"Me encantó el lugar. Súper céntrico, cerca de muchos restaurantes, bar y supermercados."
Gabriella 4-night trip
Posted 8 hours ago
Urbit Social Lofts
Hotel Provenza Garden

Hotel Provenza Garden

8/10 Good
"Limpieza del cuarto excelente!"
Leticia 3-night trip
Posted 12 hours ago
Hotel Provenza Garden
The Charlee Hotel

The Charlee Hotel

10/10 Excellent
"the staff was excellent"
Dayrell 3-night trip
Posted 1 day ago
The Charlee Hotel
Moa Select

Moa Select

10/10 Excellent
"Great Hotel, very clean and well decorated staff was great and friendly, breakfast was good, No issue at all."
Jessica 3-night trip
Posted 2 days ago
Moa Select
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

10/10 Excellent
"Great staff and location"
Oscar 3-night trip
Posted 2 days ago
Novotel Medellín El Tesoro

More cheap stays in Santa Cruz

Hotel Casa Malibú

Hotel Casa Malibú

Calle 32F 66 c 57 Medellín Medellin
$19 nightly
$19 total
Oct 8 - Oct 9
4.8/10 (3 reviews)
Hotel Casa Malibú
Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
$26 nightly
$26 total
Oct 14 - Oct 15
8.4/10 Very Good! (165 reviews)
Hostal Lleras Calle 8 - Hostel
Hotel Ofix - Laureles

Hotel Ofix - Laureles

79-86 Calle 44 Medellín
$33 nightly
$33 total
Oct 13 - Oct 14
Hotel Ofix - Laureles
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
$34 nightly
$34 total
Oct 19 - Oct 20
Autenthico Sajonia Hotel Aeropuerto
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
$63 nightly
$63 total
Oct 13 - Oct 14
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
$79 nightly
$79 total
Oct 20 - Oct 21
Masaya Medellin

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $19 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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