Title: Top Santa Rosa Department Hotels: 2026 Best Hotels in Santa Rosa Department - Expedia.com [Vacation Rentals in Santa Rosa Department](https://expedia.com/Destinations-In-Santa-Rosa-Department.d553248635975749182.Vacation-Rental-Destinations)[Santa Rosa Department Flights](https://expedia.com/Destinations-In-Santa-Rosa-Department.d553248635975749182.Flight-Destinations)[Car Rentals in Santa Rosa Department](https://expedia.com/Destinations-In-Santa-Rosa-Department.d553248635975749182.Car-Rental-Destinations)[Santa Rosa Department Vacations](https://expedia.com/Santa-Rosa-Department.d553248635975749182.Destination-Travel-Guides) ![Mendoza Wine Region showing interior views and art](https://images.trvl-media.com/place/6054200/16b6ce05-b9cd-4285-91da-7e5dcbc5a035.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6054200/16b6ce05-b9cd-4285-91da-7e5dcbc5a035.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 22 - Feb 23](https://www.expedia.com/Hotel-Search?regionId=553248635975749182&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 23 - Feb 24](https://www.expedia.com/Hotel-Search?regionId=553248635975749182&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635975749182&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248635975749182&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. 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