Photo by Southernmost Illinois Tourism Bureau

Search Vacation Homes in Southeast Illinois

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Nov 28 - Nov 30
In two weeks
Dec 5 - Dec 7
In one month
Dec 19 - Dec 21
In two months
Jan 16 - Jan 18

Vacation Homes in Southeast Illinois

Exterior detail
Small House in Pope County Eddyville, IL surrounded by Shawnee National Forest .

Small House in Pope County Eddyville, IL surrounded by Shawnee National Forest .

Eddyville
10.0 out of 10, Exceptional, (15)
"Nice place close to walking trails. Great restaurant/bar close by. "
United States
Sandy
$175 nightly
The price is $185
Nov 21 - Nov 22
Total with taxes and fees
Small House in Pope County Eddyville, IL surrounded by Shawnee National Forest .
Interior
Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna

Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna

Vienna
10.0 out of 10, Exceptional, (2)
"This was a perfect spot for us. It was cozy and clean!"
United States
Ann M.
$158 nightly
The price is $168
Nov 24 - Nov 25
Total with taxes and fees
Charming 2-bedroom barn-style home nestled on 6 acres in delightful Vienna
Exterior
Millstone Cottage

Millstone Cottage

Simpson
10.0 out of 10, Exceptional, (26)
"Great place to stay. Loved the sasquatch ambiance. "
United States
Mike F.
$204 nightly
The price is $216
Nov 24 - Nov 25
Total with taxes and fees
Millstone Cottage
Interior
Vintage Charmer on Main Street

Vintage Charmer on Main Street

Greenup
10.0 out of 10, Exceptional, (57)
"This is as a wonderful stay. The home is lovely and cared for very well. We really enjoyed our stay. "
United States
Jennifer P.
$131 nightly
The price is $138
Nov 23 - Nov 24
Total with taxes and fees
Vintage Charmer on Main Street
Property grounds
Standard Suite - Bungalow overlooking the River

Standard Suite - Bungalow overlooking the River

Golconda
9.6 out of 10, Exceptional, (26)
"We recently visited for a family reunion. The accommodations and staff were excellent!"
United States
meghan r.
$144 nightly
The price is $155
Nov 24 - Nov 25
Total with taxes and fees
Standard Suite - Bungalow overlooking the River
Fridge, microwave, oven, stovetop
Brickway Retreat

Brickway Retreat

Mattoon
9.8 out of 10, Exceptional, (38)
"Nice and clean home. "
United States
Kelly J.
$170 nightly
The price is $180
Nov 24 - Nov 25
Total with taxes and fees
Brickway Retreat
Terrace/patio
Superior Suite- Peaceful Retreat on the River

Superior Suite- Peaceful Retreat on the River

Stone Church Precinct
9.4 out of 10, Exceptional, (25)
"We book this usually twice a year,its wonderful on ohio river,easy check in"
United Kingdom
Donna d.
$165 nightly
The price is $178
Nov 24 - Nov 25
Total with taxes and fees
Superior Suite- Peaceful Retreat on the River
Exterior
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

Harrisburg
9.8 out of 10, Exceptional, (20)
"We loved our stay here! The house was charming, clean, and private, exactly what we needed for a relaxing getaway. It had a welcoming feel and gave us the perfect balance of comfort and peace. Highly recommend!"
United States
Autumn
$160 nightly
The price is $170
Nov 24 - Nov 25
Total with taxes and fees
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Fridge, microwave, oven, stovetop
Tiny home, River View near Shawnee Forest, hiking and boating Ohio River

Tiny home, River View near Shawnee Forest, hiking and boating Ohio River

Elizabethtown
10.0 out of 10, Exceptional, (56)
"Great spot for hiking Garden of the Gods, Rim Rock, Cave in Rock etc... Nice and quiet location for sleeping between hikes!"
United States
Scott F.
$211 nightly
The price is $224
Nov 24 - Nov 25
Total with taxes and fees
Tiny home, River View near Shawnee Forest, hiking and boating Ohio River
Property grounds
The Clark: Our vision of Clark Kent's 1st home with full kitchen & laundry!!!

The Clark: Our vision of Clark Kent's 1st home with full kitchen & laundry!!!

2.0 star property
Metropolis
10.0 out of 10, Exceptional, (2)
"We loved the location of this place! It was such a fun looking spot, and the hosts were very attentive and responsive. We plan again to stay here on our next trip to Metropolis!"
United States
Emma C.
$159 nightly
The price is $168
Nov 21 - Nov 22
Total with taxes and fees
The Clark: Our vision of Clark Kent's 1st home with full kitchen & laundry!!!
Living area
Beautiful home with pool in Wayne City

Beautiful home with pool in Wayne City

2.5 star property
Wayne City
10.0 out of 10, Exceptional, (1)
"Great place to stay!"
United States
Kevin D.
$231 nightly
The price is $245
Nov 21 - Nov 22
Total with taxes and fees
Beautiful home with pool in Wayne City
1 bedroom, WiFi, bed sheets
Charming 1-bedroom house in terrific Harrisburg with AC, WiFi

Charming 1-bedroom house in terrific Harrisburg with AC, WiFi

Harrisburg
9.8 out of 10, Exceptional, (9)
"Very clean, amenities were good. Loved the vintage, chic decor. Would stay again!"
United States
Sheila
$170 nightly
The price is $180
Nov 23 - Nov 24
Total with taxes and fees
Charming 1-bedroom house in terrific Harrisburg with AC, WiFi
Interior
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY

Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY

Equality
9.4 out of 10, Exceptional, (16)
"Great place to stay!"
United States
Alicia J.
$206 nightly
The price is $218
Nov 24 - Nov 25
Total with taxes and fees
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY
Smart TV
Park View Place 4 Blocks From the World's Biggest

Park View Place 4 Blocks From the World's Biggest

Casey
10.0 out of 10, Exceptional, (37)
"Nice location,friendly host,and availability of a golf cart to get around town."
United States
Barbara h.
$205 nightly
The price is $217
Nov 24 - Nov 25
Total with taxes and fees
Park View Place 4 Blocks From the World's Biggest
Exterior
Superior Suite w/ Full Kitchen on the Bluff

Superior Suite w/ Full Kitchen on the Bluff

Stone Church Precinct
8.4 out of 10, Very Good, (12)
"So quiet and peaceful! Enjoyed our stay! "
United States
Margaret I.
$165 nightly
The price is $178
Nov 24 - Nov 25
Total with taxes and fees
Superior Suite w/ Full Kitchen on the Bluff
Interior
New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!

New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!

Olney
10.0 out of 10, Exceptional, (55)
"Nice place to stay"
United States
Eddie M.
$158 nightly
The price is $167
Nov 24 - Nov 25
Total with taxes and fees
New listing! Private 3 bedroom 2 bath home with BEAUTIFUL sunroom!
Fridge, microwave, oven, stovetop
Eagle's Nest near Eagle Creek State Park

Eagle's Nest near Eagle Creek State Park

Findlay
9.2 out of 10, Wonderful, (15)
"Amazing host and property. "
United States
Nicholas K.
$205 nightly
The price is $217
Nov 23 - Nov 24
Total with taxes and fees
Eagle's Nest near Eagle Creek State Park
Interior
Charming 2-bedroom bungalow plus full size bed, and outdoor space.

Charming 2-bedroom bungalow plus full size bed, and outdoor space.

Olney
10.0 out of 10, Exceptional, (1)
"Very clean house that was just right for me and my family. Supplied basically everything we needed for our four night stay. Center of town so very close to everything. Thank you, Joni and Jason!"
United States
Tyler B.
$248 nightly
The price is $263
Nov 21 - Nov 22
Total with taxes and fees
Charming 2-bedroom bungalow plus full size bed, and outdoor space.
Outdoor dining
Relax at Pond View Loft—your cozy barn-top retreat with pond views, fires, and fishing fun.

Relax at Pond View Loft—your cozy barn-top retreat with pond views, fires, and fishing fun.

Thompsonville
8.8 out of 10, Excellent, (6)
"The property fully met our needs. Rustic and lots of space for the dogs to run."
Canada
Beth B.
$335 nightly
The price is $353
Dec 7 - Dec 8
Total with taxes and fees
Relax at Pond View Loft—your cozy barn-top retreat with pond views, fires, and fishing fun.
Fridge, microwave, oven, stovetop
Fish, boat, grill, chill, pets, relax

Fish, boat, grill, chill, pets, relax

Sullivan
9.6 out of 10, Exceptional, (58)
"The condo is nice and clean, and so close to the lake. The experience has been wonderful, and Stacey is great to work with. It backs right up to the golf course, a short walk to the campgrounds, and an easy trail to the lake. "
United States
Audrey M.
$248 nightly
The price is $263
Nov 30 - Dec 1
Total with taxes and fees
Fish, boat, grill, chill, pets, relax
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southeast Illinois Hotel Reviews

Drury Inn & Suites Paducah

Drury Inn & Suites Paducah

10/10 Excellent
"Great all around experience!"
Patrick 1-night trip
Posted 3 days ago
Drury Inn & Suites Paducah

Find out more about Southeast Illinois

Southeast Illinois Vacation Homes information

Number of reviews
Accommodation
 Vacation Homes
Lowest Price
Highest Price

Explore a world of travel with Expedia