Step off the lively streets and into a soothing place of prayer at Cathedral of Isernia. You can indulge in a few moments of contemplation here.
When you've finished up at this Isernia principal church, why not check out Basilica Minore dell'Addolorata, National Museum of the Paleolithic, and Fontana Fraterna? They're not too far from Cathedral of Isernia and also a hit with many travelers.