Rochester Central Business District Vacations from $429

Book a Hotel + Flight or Car together to unlock savings

Photo by Guy Coniglio
  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Rochester Central Business District Vacation

Experience everything Rochester Central Business District has to offer with a Rochester Central Business District vacation package. From its shopping and history to its dining and more, prepare to be captivated by this riverside neighborhood. When it's time to explore the sights, you'll find loads of top attractions nearby including Genesee Rivers High Falls, University of Rochester and Strong. Tick off one, two or all during your trip to Rochester Central Business District. Stop daydreaming and start doing. When it's time to lock in your vacation to Rochester Central Business District, Expedia will help you get there.

The Latest Rochester Central Business District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Regency Rochester
RIT Inn & Conference Center
School 31 Lofts at Colors Studios
Inn on Broadway
The Del Monte Lodge Renaissance Rochester Hotel & Spa

Where to stay in Rochester Central Business District

Find the best Rochester Central Business District areas and neighborhoods for the activities you enjoy most. Learn more about Rochester Central Business District

Rochester Central Business District Hotel Deals

Hyatt Regency Rochester

Hyatt Regency Rochester

3.5 out of 5
125 East Main Street Rochester NY
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $119 total per night from Nov 8 to Nov 9
$119 total
Nov 8 - Nov 9
Total with taxes and fees
Hyatt Regency Rochester
Hampton Inn & Suites Rochester Downtown

Hampton Inn & Suites Rochester Downtown

2.5 out of 5
101 South Union Street Rochester NY
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $183 total per night from Nov 15 to Nov 16
$183 total
Nov 15 - Nov 16
Total with taxes and fees
Hampton Inn & Suites Rochester Downtown
Hilton Garden Inn Rochester Downtown, NY

Hilton Garden Inn Rochester Downtown, NY

3 out of 5
155 E Main St Rochester NY
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $153 total per night from Nov 15 to Nov 16
$153 total
Nov 15 - Nov 16
Total with taxes and fees
8.2/10 Very Good! (962 reviews)
"Clean Easy walk to Water Street. Good restaura nts around and ate at the hotel too."

Reviewed on Nov 2, 2026

Hilton Garden Inn Rochester Downtown, NY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Rochester Central Business District attractions

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.