La Misión Vacations from $649

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Your La Misión Vacation

Discover all the amazing things this neighborhood has to offer with a customized La Misión vacation package. However you picture yourself spending your days here, you'll find endless opportunities for fun, relaxation and adventure. When it's time to head out and explore, you'll find loads of top attractions nearby including Los Pioneros Park, Plaza Tutuli Shopping Center and H. Cajeme Town Hall. Tick off one, two or all during your trip to La Misión. Stop daydreaming and start doing. When it's time to lock in your next vacation to La Misión, Expedia will help you get there.

The Latest La Misión Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Obregon

Hotel Obregon

3 out of 5
Price was $673, price is now $649 per person
$649
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Ciudad Obregón (CEN)
6.8/10 (73 reviews)
El cuarto contaba con alfombra ya desgastada, recomendaria cambiarla o cambiar el piso.

Reviewed on Oct 2, 2024

InHouse Obregón

InHouse Obregón

4 out of 5
Price was $858, price is now $684 per person
$684
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Ciudad Obregón (CEN)
8.6/10 Excellent! (319 reviews)
Hotel muy bien, solamente que la limpieza durante la estadía en la habitación fue muy superficial

Reviewed on Aug 11, 2025

Hotel Yori

Hotel Yori

3 out of 5
Price was $681, price is now $650 per person
$650
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Ciudad Obregón (CEN)
6.6/10 (155 reviews)
Exelent attention end service

Reviewed on Jun 23, 2025

Holiday Inn Express & Suites Ciudad Obregon by IHG

Holiday Inn Express & Suites Ciudad Obregon by IHG

3 out of 5
Price was $849, price is now $823 per person
$823
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Ciudad Obregón (CEN)
9.2/10 Wonderful! (643 reviews)
Bed was comfortable, suite very spacious. Loved that they always had coffee

Reviewed on Aug 11, 2025

Wyndham Garden Ciudad Obregon

Wyndham Garden Ciudad Obregon

4.5 out of 5
Price was $720, price is now $707 per person
$707
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Guatemala City (GUA) to Ciudad Obregón (CEN)
8/10 Very Good! (600 reviews)
Pool was a mess and the light fixture hanging out

Reviewed on Sep 3, 2025

La Misión Hotel Deals

Hotel Yori

Hotel Yori

3 out of 5
Miguel Alemán 770 Norte, Cajeme, SON
Fully refundableReserve now, pay when you stay
$38 nightly
The price is $46 total per night from Sep 8 to Sep 9
$46 total
Sep 8 - Sep 9
Total with taxes and fees
Hotel Yori
InHouse Obregón

InHouse Obregón

4 out of 5
Av Alemán y Tetabiate s/n, Ciudad Obregón, Cajeme, SON
Fully refundable
Get rates
InHouse Obregón
Fiesta Inn Express Ciudad Obregón

Fiesta Inn Express Ciudad Obregón

3.5 out of 5
Ave Miguel Aleman 755 Norte, Cajeme, SON
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $101 total per night from Sep 19 to Sep 20
$101 total
Sep 19 - Sep 20
Total with taxes and fees
Fiesta Inn Express Ciudad Obregón
See all 41 properties in La Misión
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in La Misión

Estadio Yaquis Stadium

Catch an event at Estadio Yaquis Stadium during your trip to Ciudad Obregón. Discover the restaurants and its festivals while you're in the area.

Estadio Yaquis Stadium

Nainari Lake

Commune with nature and explore the great outdoors at Nainari Lake during your travels in Ciudad Obregón. Discover the restaurants and its festivals while you're in the area.

Nainari Lake

Plaza Cocorit

Explore the great outdoors at Plaza Cocorit, a lovely green space in Cócorit.

Plaza Cocorit
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.