Palo Seco Vacations from $517

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Palo Seco Vacation

When a fun city getaway is calling, answer it with a vacation package to Palo Seco. The neighborhood of Barrio Pueblo, which is good for history, views and walking, makes a wonderful base for your adventures. A trip to Palo Seco is an ideal opportunity to sightsee. Be sure to look around popular attractions like San Juan Gate, La Fortaleza and Catedral Basilica Menor de San Juan Bautista. Expedia can help you escape your daily routine. Tailor your vacation to Palo Seco to suit your travel style, whatever that may look like.

The Latest Palo Seco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Puerto Valdes

Hotel Puerto Valdes

4 out of 5
San Juan Antiguo
Save 100% on your flight
Price was $947, price is now $517 per person
$517
per person
Feb 8 - Feb 13
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9/10 Wonderful! (500 reviews)
Very modern and clean. We stayed in the penthouse that is extremely spacious. Attentive staff and welcoming.

Reviewed on Nov 24, 2025

The Oliver Hotel

The Oliver Hotel

3 out of 5
San Juan Antiguo
Price was $1,261, price is now $596 per person
$596
per person
Feb 8 - Feb 13
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9/10 Wonderful! (50 reviews)
Centrico, comodo, perfecto para estar cerca de todo y tener tranquilidad

Reviewed on Nov 28, 2025

OLV Fifty Five - Adults Only

OLV Fifty Five - Adults Only

4.5 out of 5
Condado
Price was $2,972, price is now $1,464 per person
$1,464
per person
Jan 15 - Jan 20
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.6/10 Excellent! (577 reviews)
The staff was amazing, best hotel stay I’ve had in awhile

Reviewed on Nov 30, 2025

El Colonial - Adults Only

El Colonial - Adults Only

3.5 out of 5
Old San Juan
Save 100% on your flight
Price was $2,049, price is now $1,134 per person
$1,134
per person
Feb 21 - Feb 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
9.4/10 Exceptional! (1,399 reviews)
Clean room, very attentive staff and great amenities. Love the fact that is very private and quite around the hallways and lobby. Open bar and close to a lot of great restaurants. Highly recommend

Reviewed on Dec 3, 2025

Fortaleza Suites

Fortaleza Suites

3.5 out of 5
Old San Juan
Save 100% on your flight
Price was $1,513, price is now $840 per person
$840
per person
Feb 21 - Feb 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
9/10 Wonderful! (1,175 reviews)
Phenomenal staff great place. Absolutely beautiful.

Reviewed on Dec 5, 2025

Where to stay in Palo Seco

Find the best Palo Seco areas and neighborhoods for the activities you enjoy most. Learn more about Palo Seco
San Juan

Old San Juan

4.5/5(354 area reviews)

The fascinating museums and captivating waterfront views are top of the list for many visitors to Old San Juan. A stop by Port of San Juan or Pier 4 might round out your trip.

Find hotels in Old San Juan

Palo Seco Hotel Deals

Aqua by Dreams Hotel

Aqua by Dreams Hotel

2 out of 5
PR-870 Toa Baja
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $186 total per night from Dec 6 to Dec 7
$186 total
Dec 6 - Dec 7
Total with taxes and fees
8.6/10 Excellent! (147 reviews)
Enjoyed our stay. The room were every clean and orderly and the stall was very friendly and accommodating. We could not speak Spanish and they went out of their way to help us and things for the room and ordering food. Would stay again.

Reviewed on Nov 16, 2025

Aqua by Dreams Hotel
Hyatt Vacation Club at Hacienda del Mar, Dorado

Hyatt Vacation Club at Hacienda del Mar, Dorado

3.5 out of 5
301 Hwy 693 Vega Alta
Fully refundable
$214 nightly
The price is $233 total per night from Dec 15 to Dec 16
$233 total
Dec 15 - Dec 16
Total with taxes and fees
9.2/10 Wonderful! (2,927 reviews)
Room was not spotless, but did have a comfortable bed, all the amenities we needed, and a tremendous view.

Reviewed on Dec 4, 2025

Hyatt Vacation Club at Hacienda del Mar, Dorado
The Condado Plaza Hotel

The Condado Plaza Hotel

4 out of 5
999 Ashford Avenue San Juan
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $224 total per night from Dec 14 to Dec 15
$224 total
Dec 14 - Dec 15
Total with taxes and fees
7.8/10 Good! (1,856 reviews)
Every thing was fine

Reviewed on Dec 2, 2025

The Condado Plaza Hotel
See all 3,679 properties in Palo Seco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Palo Seco

Isla de Cabras

Commune with nature and explore the great outdoors at Isla de Cabras during your travels in Toa Baja. Discover the area's top-notch restaurants and its acclaimed art scene.

Isla de Cabras

Fortin San Juan de la Cruz

You can find out about the history of Toa Baja when you stop by Fortin San Juan de la Cruz. Stroll along the area's beautiful beaches or experience its acclaimed art scene.

Fortin San Juan de la Cruz

Things to do

Puerto Rico: UTV and Can-Am Sightseeing Tours

Puerto Rico: UTV and Can-Am Sightseeing Tours

$68
per adult
76% of travellers recommend
Puerto Rico: UTV and Can-Am Sightseeing Tours
Single female snorkeler in the ocean off the coast of Puerto Rico

Catamaran Sail & Snorkeling in the Caribbean with Lunch

$184
per traveler
90% of travellers recommend
Catamaran Sail & Snorkeling in the Caribbean with Lunch
San Juan: Old San Juan Sunset Cruise with Drinks & Transfer

San Juan: Old San Juan Sunset Cruise with Drinks & Transfer

$99
per adult
90% of travellers recommend
San Juan: Old San Juan Sunset Cruise with Drinks & Transfer
See all activities in San Juan
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.