Panama Vacations from $278

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The Latest Panama vacation packages

Price found within the past 48 hours. Click for updated prices.
The Inn & Suites Omaha near ZOO

The Inn & Suites Omaha near ZOO

2.5 out of 5
Price was $388, price is now $278 per person
$278
per person
Oct 30 - Nov 2
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Omaha (OMA)
4.6/10 (1,001 reviews)
It was ok but not the best hotel

Reviewed on Jul 27, 2025

Home2 Suites by Hilton Omaha I-80 at 72nd Street, NE

Home2 Suites by Hilton Omaha I-80 at 72nd Street, NE

3 out of 5
South Central Omaha
Price was $392, price is now $329 per person
$329
per person
Oct 30 - Nov 2
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Omaha (OMA)
9.4/10 Exceptional! (258 reviews)
This hotel was amazing! As soon as you enter, they greet you with a little bag of goodies. The rooms are super clean. The breakfast options were limited, but still pretty good. Definitely 5 out 5 stars!

Reviewed on Sep 2, 2025

Travelodge by Wyndham Missouri Valley

Travelodge by Wyndham Missouri Valley

2.5 out of 5
Price was $345, price is now $294 per person
$294
per person
Oct 30 - Nov 2
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Omaha (OMA)
8/10 Very Good! (257 reviews)
It was fine for what it is, a railroad crews place to stay when they tie up for the day. Everyone was quiet and courteous. The dining place has good food, clean place and a bit of nostalgia to boot. I have stayed in places like this before when I worked for the Railroad. It was very quiet for sleeping. Everyone was respectful in that they all knew there could be people sleeping at all hours.

Reviewed on Aug 8, 2025

Omaha Marriott

Omaha Marriott

4 out of 5
Central Omaha
Price was $392, price is now $339 per person
$339
per person
Oct 30 - Nov 2
found 24 hours ago
Roundtrip flight included
Denver (DEN) to Omaha (OMA)
8.2/10 Very Good! (1,005 reviews)
Great property and location

Reviewed on Aug 30, 2025

Aloft Omaha West

Aloft Omaha West

3 out of 5
Price was $748, price is now $649 per person
$649
per person
Nov 26 - Nov 30
found 2 hours ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Omaha (OMA)
8.4/10 Very Good! (358 reviews)
Very nice hotel and reasonable.

Reviewed on Sep 1, 2025

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Panama Hotel Deals

Cobblestone Inn & Suites - Avoca

Cobblestone Inn & Suites - Avoca

2.5 out of 5
7013 N Chestnut St, Avoca, IA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from Sep 10 to Sep 11
$134 total
Sep 10 - Sep 11
Total with taxes and fees
Cobblestone Inn & Suites - Avoca
Motel 6 Avoca, IA

Motel 6 Avoca, IA

2 out of 5
211 West Marty Drive, Exit 40 on I-80 and Highway 59, Avoca, IA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Sep 9 to Sep 10
$81 total
Sep 9 - Sep 10
Total with taxes and fees
Motel 6 Avoca, IA
Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

2 out of 5
1614 Antique City Drivie, Walnut, IA
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Sep 16 to Sep 17
$71 total
Sep 16 - Sep 17
Total with taxes and fees
Econo Lodge Inn & Suites
See all 18 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Panama vacation package cost?
You'll find cheap prices from $278 on Expedia for your Panama break. However, factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Panama costs.
What are the cheapest months to go to Panama?
If you're looking to snag a cheap Panama vacation package, consider planning a trip in January, June and December. You'll typically find better rates on airfares and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Panama?
The ideal length of your Panama vacation depends on what you'd like to do and see. Generally, a few days to a week will give you plenty of time to check out all the leading attractions and explore some hidden spots along the way.
How to find the best Panama package deals?
Begin your search for a Panama package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Panama package deal right away, just switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Panama escape underway.
Is it cheaper to book a Panama vacation as a package?
You can enjoy significant savings on your next Panama retreat by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to see some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Panama?
If you have your Panama vacation dates confirmed, book as soon as you can to grab some awesome deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for quick escapes.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
If you're like us, you love traveling but don't love the price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Panama break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.