Title: Santee Vacation Rentals from $120: Search Short-Term Rentals | Expedia.com

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![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee vacation rentals

![Property grounds](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/14910802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/3c5e3a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/224b7c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/c80eacb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

[](https://www.expedia.com/Santee-Hotels-Peaceful-Condo-On-Lake-Marion-In-Santee.h107471514.Hotel-Information)

Santee

10/10

Exceptional

(11 reviews)

"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Greg M.

$463 nightly

$514 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-Peaceful-Condo-On-Lake-Marion-In-Santee.h107471514.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/603142c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/3c1a66e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/24aca905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/af4781e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

[](https://www.expedia.com/Santee-Hotels-LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks.h126119247.Hotel-Information)

Santee

$444 nightly

$493 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks.h126119247.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/876cda77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/bf924ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/26332b61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/0c397544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country living lake style near Santee 

[](https://www.expedia.com/Sumter-Hotels-Country-Living-Lake-Style.h68032053.Hotel-Information)

Summerton

10/10

Exceptional

(42 reviews)

"Great stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tim E.

$190 nightly

$211 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Sumter-Hotels-Country-Living-Lake-Style.h68032053.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/3f704424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/fa6eea82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/3c8491d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/d1570709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Resting Spot just off I95\. 12 miles west on hwy 6.

[](https://www.expedia.com/Elloree-Hotels-Country-Resting-Spot.h107431587.Hotel-Information)

Elloree

9.4/10

Exceptional

(22 reviews)

"Enjoyed the stay. Out in the country, Great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marty D.

$150 nightly

$167 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Country-Resting-Spot.h107431587.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/bb6f3418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/74aa2f29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/70635ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/7f1c7042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hobbs Haven at Lake Marion

[](https://www.expedia.com/Summerton-Hotels-Hobbs-Haven-At-Lake-Marion.h104470344.Hotel-Information)

Summerton

9.4/10

Exceptional

(12 reviews)

"Great opportunity for family time!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

faye c.

$320 nightly

$355 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Hobbs-Haven-At-Lake-Marion.h104470344.Hotel-Information)

![TV, table tennis](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/b1457367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/d950643a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, internet, bed sheets](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/a0c890ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/85826adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Turtle Cove - Lake Living on Lake Marion

[](https://www.expedia.com/Summerton-Hotels-Turtle-Cove-Lake-Living-On-Lake-Marion.h119463617.Hotel-Information)

Summerton

$379 nightly

$431 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Turtle-Cove-Lake-Living-On-Lake-Marion.h119463617.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/f4e6785a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/3d5346d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/eb799bdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/8fe42751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6 

[](https://www.expedia.com/Summerton-Hotels-Cozy-Lakefront-Tiny-Cabin-On-Lake-Marion-With-An-Amazing-View-And-Pet-Friendly.h108017538.Hotel-Information)

Summerton

9.2/10

Wonderful

(22 reviews)

"Overall an excellent stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andy K.

$158 nightly

$176 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Cozy-Lakefront-Tiny-Cabin-On-Lake-Marion-With-An-Amazing-View-And-Pet-Friendly.h108017538.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/dd2731f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/825609ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/5efa65bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, video games](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/870c37c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Camping Cabin on Lake Marion near Congaree Nat Park

[](https://www.expedia.com/Pinewood-Hotels-Cozy-Camping-Cabin-On-Lake-Marion-Near-Congaree-Nat-Park.h91012626.Hotel-Information)

Rimini

8.2/10

Very Good

(14 reviews)

"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Derrick W.

$120 nightly

$133 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Pinewood-Hotels-Cozy-Camping-Cabin-On-Lake-Marion-Near-Congaree-Nat-Park.h91012626.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/6d916484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/15980f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/24b16566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/dae68d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pet friendly country cottage with large fenced-in yard & horses on property

[](https://www.expedia.com/Holly-Hill-Hotels-Come-Relax-In-The-Country.h95993146.Hotel-Information)

Holly Hill

10/10

Exceptional

(138 reviews)

"Great stay! The host was very polite and communicative."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony T.

$195 nightly

$216 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Holly-Hill-Hotels-Come-Relax-In-The-Country.h95993146.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/09093a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/86e8c2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/612c203e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/5bfe4281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin at the lake in Rimini, SC

[](https://www.expedia.com/Pinewood-Hotels-Cabin-At-The-Lake-In-Rimini.h91218225.Hotel-Information)

Rimini

7.8/10

Good

(7 reviews)

"Great view, excellent communication with the owners, relaxing, peaceful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christie

$128 nightly

$142 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Pinewood-Hotels-Cabin-At-The-Lake-In-Rimini.h91218225.Hotel-Information)

![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bells Marina & Resort

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

Eutawville

8.6/10

Excellent

(90 reviews)

"Super quaint, quiet, nice little get away."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

$108 nightly

$120 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/a01795f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/16d477ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/efc54769.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/9b473e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

[](https://www.expedia.com/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information)

Holly Hill

10/10

Exceptional

(8 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hayden S.

$145 nightly

$161 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/65da7b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/bee5a8ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/9589b5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/2f19f48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Modern apartment overlooking historic downtown Elloree, SC.

[](https://www.expedia.com/Elloree-Hotels-Modern-Apartment-Overlooking-Historic-Downtown-Elloree.h114282854.Hotel-Information)

Elloree

$119 nightly

$132 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Modern-Apartment-Overlooking-Historic-Downtown-Elloree.h114282854.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/fe01674b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/d3f371be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/4a84e798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/8aaa8970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sweet Marion - Dock + Boat Ramp + Hot Tub!

[](https://www.expedia.com/Summerton-Hotels-Sweet-Marion-Dock-Boat-Ramp-Hot-Tub.h104523088.Hotel-Information)

Summerton

8.6/10

Excellent

(19 reviews)

"Nice comfortable place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dylan H.

$439 nightly

$499 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Sweet-Marion-Dock-Boat-Ramp-Hot-Tub.h104523088.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/62aee6da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/w1057h775x63y0-6c79090c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/w1031h771x0y4-77b734eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/2ac0ad5e_edited_fd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Tee Vee Cove is the place to be located near great golfing, fishing and food

[](https://www.expedia.com/Elloree-Hotels-The-Tee-Vee-Cove-Is-The-Place-To-Be-Located-Near-Great-Golfing.h123608930.Hotel-Information)

Elloree

$232 nightly

$258 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-The-Tee-Vee-Cove-Is-The-Place-To-Be-Located-Near-Great-Golfing.h123608930.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/38650b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/aff09b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/00cecc0b_edited_986a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/1bbbbe9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

[](https://www.expedia.com/Beautiful-Country-Cottage-With-Ease-Of-Access-Minutes-To-I-26.h76591706.Hotel-Information)

Bowman

9.8/10

Exceptional

(32 reviews)

"Will stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert B.

$155 nightly

$172 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Beautiful-Country-Cottage-With-Ease-Of-Access-Minutes-To-I-26.h76591706.Hotel-Information)

![TV, fireplace](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/4b88cd29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/52ad34c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/92effdbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Oven, stovetop](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/113f5a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Farm Stay on 30-Acres

[](https://www.expedia.com/Summerton-Hotels-A-Private-Cozy-Cabin-In-The-Country.h124483821.Hotel-Information)

Summerton

$407 nightly

$452 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-A-Private-Cozy-Cabin-In-The-Country.h124483821.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/ec7cddf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/0949138a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/9b1fe174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/431a876d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

[](https://www.expedia.com/Summerton-Hotels-SANITIZED-Lake-Marion-Lakefront-Sandy-Beach.h19993568.Hotel-Information)

Summerton

9.6/10

Exceptional

(249 reviews)

"We had a great family retreat "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ernestine C.

$455 nightly

$505 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-SANITIZED-Lake-Marion-Lakefront-Sandy-Beach.h19993568.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1198h1600x0y0-8fa30947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/c0703344.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1197h1600x0y0-a4a4fa86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/d8b442d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful brick home w/ large porch and 3 bedrooms

[](https://www.expedia.com/Beautiful-Brick-Home-W-Large-Porch-And-3-Bedrooms.h112528151.Hotel-Information)

Bowman

9.2/10

Wonderful

(5 reviews)

"Nice and quiet property. It served us well for the weekend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mick S.

$253 nightly

$280 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Beautiful-Brick-Home-W-Large-Porch-And-3-Bedrooms.h112528151.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/43244fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/3ffc5e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/e994b052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/1236d280.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Stylish One Bedroom Apartment 

[](https://www.expedia.com/Elloree-Hotels-Spacious-Stylish-One-Bedroom-Apartment.h95766315.Hotel-Information)

Elloree

8.0/10

Very Good

(1 review)

"Very nice home! Pictures are as advertised and the home was very clean. The area surrounding the home is dilapidated, however, the home is very nice. The only two issues with the house are 1) the walls are very thin and you can hear the road noise and every step the people above take very clearly. 2) there is an issue with the municipal pipes of the town and my last night of the stay the water in the shower and bathroom sink was coming out yellow. Overall a very nice option in this small town."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joshua S.

$260 nightly

$289 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Spacious-Stylish-One-Bedroom-Apartment.h95766315.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=COTTAGE)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=CONDO)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-04&d1=2026-06-04&endDate=2026-06-07&d2=2026-06-07&lodging=APARTMENT)

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## Top Santee Hotel Reviews

![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg)

### Best Western Plus Santee Inn

8/10 Good

"Clean and comfortable ,"

[](https://expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg)

### Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

"Clean and comfortable room. Pleasant staff and good location "

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg)

### Tru By Hilton Santee

10/10 Excellent

"It is conveniently located off I-95\. The property was clean. The staff was friendly and even gave us restaurant recommendations that we enjoyed."

[](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![SpringHill Suites by Marriott Orangeburg](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69_y.jpg)

### SpringHill Suites by Marriott Orangeburg

4/10 Poor

"The night stand was stained with red and pink. The mop board was fall off the wall. Tags from clothing on the floor. The bartender was personable but had no knowledge that white wine is served chilled. Bottle of wine came out of a closet. The bottle of lotion provided by the hotel was half empty. I inquired at the front desk about getting another and was told that she could not. "

[](https://expedia.com/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information)

![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg)

### Baymont by Wyndham Santee

6/10 Okay

"No hot water for shower, however, oddly the sink did have hot water. Perhaps the shower head was faulty."

[](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg)

### Hampton Inn Santee-I-95

10/10 Excellent

"Parking easy. Friendly, helpful staff. Quiet room with a comfortable bed. A good night’s sleep in a nice area."

[](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg)

### Fairfield Inn by Marriott Orangeburg

6/10 Okay

"The 7 day policy of not cleaning or changing linen on a day to day or even every other day is totally unacceptable. Only supplying clean towels and linen IF requested also unacceptable."

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information)

![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg)

### Comfort Inn & Suites Santee

10/10 Excellent

"Hotel was a little dated but clean."

[](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information)

![Red Roof Inn Santee](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d_y.jpg)

### Red Roof Inn Santee

2/10 Terrible

"I haven’t be returned my $50 security yet "

[](https://expedia.com/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information)

## Find out more about Santee

**Everything you need to know about Santee vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santee vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santee rentals**

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santee

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- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Santee ](https://expedia.com/Santee-Private-Vacation-Homes.d9953-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cottages in Santee ](https://expedia.com/Santee-Cottages.d9953-aaCottages.Travel-Guide-Accommodation)
- [Motels in Santee ](https://expedia.com/Santee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)
- [Condo Rentals in Santee ](https://expedia.com/Santee-Condos.d9953-aaCondos.Travel-Guide-Accommodation)
- [Apartments in Santee ](https://expedia.com/Santee-Apartments.d9953-aaApartments.Travel-Guide-Accommodation)
- [Cabin Rentals in Santee ](https://expedia.com/Santee-Cabins.d9953-aaCabins.Travel-Guide-Accommodation)
- [Resorts in Santee ](https://expedia.com/Santee-Resorts.d9953-aaResorts.Travel-Guide-Accommodation)
- [Aparthotels in Santee ](https://expedia.com/Santee-Apart-Hotels.d9953-aaApartHotels.Travel-Guide-Accommodation)
- [RV Parks in Santee ](https://expedia.com/Santee-RV-Parks.d9953-aaRVParks.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find vacation rentals in Santee?

### What are some of the best vacation home rentals in Santee?

### How many vacation rentals are there in Santee?

### What can I see and do in Santee?

### What are vacation rentals like in Santee?

### Expedia's Latest Trends

Hotels

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Flights

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- [Cheap Flights to Charleston](https://expedia.com/Cheap-Flights-To-Charleston.d179997.Travel-Guide-Flights)
- [Cheap Flights to Hilton Head Island](https://expedia.com/Cheap-Flights-To-Hilton-Head-Island.d601684.Travel-Guide-Flights)
- [Cheap Flights to Myrtle Beach](https://expedia.com/Cheap-Flights-To-Myrtle-Beach.d601685.Travel-Guide-Flights)

Cars

- [Car rentals in Columbia](https://expedia.com/Car-Rentals-In-Columbia.d764.Car-Rental-Guide)
- [Car rentals in Charleston](https://expedia.com/Car-Rentals-In-Charleston.d179997.Car-Rental-Guide)
- [Car rentals in Myrtle Beach](https://expedia.com/Car-Rentals-In-Myrtle-Beach.d601685.Car-Rental-Guide)
- [Car rentals in Greenville](https://expedia.com/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)

Cruises

- [Cruises from Charleston](https://expedia.com/Cruises-from-Charleston.d179997.Cruise-Departure-Port)

Activities

- [Things to do in Myrtle Beach](https://expedia.com/Things-To-Do-In-Myrtle-Beach.d601685.Travel-Guide-Activities)

Packages

- [Myrtle Beach Vacation](https://expedia.com/Myrtle-Beach.d601685.Destination-Travel-Guides)

Vacation Rentals

- [Myrtle Beach Vacation Rentals](https://expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)

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