Title: Santee Vacation Rentals from $120: Search Short-Term Rentals | Expedia.com

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![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee vacation rentals

![Property grounds](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/14910802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/3c5e3a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/c80eacb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/224b7c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

[](https://www.expedia.com/Santee-Hotels-Peaceful-Condo-On-Lake-Marion-In-Santee.h107471514.Hotel-Information)

Santee

10/10

Exceptional

(11 reviews)

"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Greg M.

$463 nightly

$514 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-Peaceful-Condo-On-Lake-Marion-In-Santee.h107471514.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/603142c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/24aca905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/af4781e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126120000/126119300/126119247/b2524d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

[](https://www.expedia.com/Santee-Hotels-LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks.h126119247.Hotel-Information)

Santee

$444 nightly

$493 total

Mar 18 - Mar 19

Total with taxes and fees

[](https://www.expedia.com/Santee-Hotels-LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks.h126119247.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/876cda77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/bf924ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/0c397544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/69000000/68040000/68032100/68032053/ed7f19cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country living lake style near Santee 

[](https://www.expedia.com/Sumter-Hotels-Country-Living-Lake-Style.h68032053.Hotel-Information)

Summerton

10/10

Exceptional

(42 reviews)

"Great stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tim E.

$190 nightly

$211 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Sumter-Hotels-Country-Living-Lake-Style.h68032053.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/3f704424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/d1570709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/9998f4d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/fa6eea82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Resting Spot just off I95\. 12 miles west on hwy 6.

[](https://www.expedia.com/Elloree-Hotels-Country-Resting-Spot.h107431587.Hotel-Information)

Elloree

9.4/10

Exceptional

(22 reviews)

"Enjoyed the stay. Out in the country, Great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marty D.

$150 nightly

$167 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Country-Resting-Spot.h107431587.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/bb6f3418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/70635ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/9118d20a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104480000/104470400/104470344/7f1c7042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hobbs Haven at Lake Marion

[](https://www.expedia.com/Summerton-Hotels-Hobbs-Haven-At-Lake-Marion.h104470344.Hotel-Information)

Summerton

9.4/10

Exceptional

(12 reviews)

"Great opportunity for family time!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

faye c.

$320 nightly

$355 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Hobbs-Haven-At-Lake-Marion.h104470344.Hotel-Information)

![TV, table tennis](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/b1457367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Game room](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/1dfe7a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/85826adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/d950643a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Turtle Cove - Lake Living on Lake Marion

[](https://www.expedia.com/Summerton-Hotels-Turtle-Cove-Lake-Living-On-Lake-Marion.h119463617.Hotel-Information)

Summerton

$379 nightly

$431 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Turtle-Cove-Lake-Living-On-Lake-Marion.h119463617.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/f4e6785a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/eb799bdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/3d5346d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/109000000/108020000/108017600/108017538/c1d4935b_edited_e25c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6 

[](https://www.expedia.com/Summerton-Hotels-Cozy-Lakefront-Tiny-Cabin-On-Lake-Marion-With-An-Amazing-View-And-Pet-Friendly.h108017538.Hotel-Information)

Summerton

9.2/10

Wonderful

(22 reviews)

"Overall an excellent stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andy K.

$158 nightly

$176 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Cozy-Lakefront-Tiny-Cabin-On-Lake-Marion-With-An-Amazing-View-And-Pet-Friendly.h108017538.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/dd2731f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/e5dece1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, video games](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/870c37c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91020000/91012700/91012626/825609ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Camping Cabin on Lake Marion near Congaree Nat Park

[](https://www.expedia.com/Pinewood-Hotels-Cozy-Camping-Cabin-On-Lake-Marion-Near-Congaree-Nat-Park.h91012626.Hotel-Information)

Rimini

8.2/10

Very Good

(14 reviews)

"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Derrick W.

$120 nightly

$133 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Pinewood-Hotels-Cozy-Camping-Cabin-On-Lake-Marion-Near-Congaree-Nat-Park.h91012626.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/6d916484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/24b16566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/cc0e968f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/15980f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pet friendly country cottage with large fenced-in yard & horses on property

[](https://www.expedia.com/Holly-Hill-Hotels-Come-Relax-In-The-Country.h95993146.Hotel-Information)

Holly Hill

10/10

Exceptional

(138 reviews)

"Great stay! The host was very polite and communicative."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony T.

$195 nightly

$216 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Holly-Hill-Hotels-Come-Relax-In-The-Country.h95993146.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/09093a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/612c203e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/86e8c2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218225/5bfe4281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin at the lake in Rimini, SC

[](https://www.expedia.com/Pinewood-Hotels-Cabin-At-The-Lake-In-Rimini.h91218225.Hotel-Information)

Rimini

7.8/10

Good

(7 reviews)

"Great view, excellent communication with the owners, relaxing, peaceful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christie

$128 nightly

$142 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Pinewood-Hotels-Cabin-At-The-Lake-In-Rimini.h91218225.Hotel-Information)

![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bells Marina & Resort

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

Eutawville

8.6/10

Excellent

(90 reviews)

"Super quaint, quiet, nice little get away."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

$108 nightly

$120 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/a01795f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/16d477ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/efc54769.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/495777fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

[](https://www.expedia.com/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information)

Holly Hill

10/10

Exceptional

(8 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hayden S.

$145 nightly

$161 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/65da7b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/9589b5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/2f19f48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/bee5a8ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Modern apartment overlooking historic downtown Elloree, SC.

[](https://www.expedia.com/Elloree-Hotels-Modern-Apartment-Overlooking-Historic-Downtown-Elloree.h114282854.Hotel-Information)

Elloree

$119 nightly

$132 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Modern-Apartment-Overlooking-Historic-Downtown-Elloree.h114282854.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/fe01674b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/8aaa8970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/d3f371be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/4a84e798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sweet Marion - Dock + Boat Ramp + Hot Tub!

[](https://www.expedia.com/Summerton-Hotels-Sweet-Marion-Dock-Boat-Ramp-Hot-Tub.h104523088.Hotel-Information)

Summerton

8.6/10

Excellent

(19 reviews)

"Nice comfortable place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dylan H.

$444 nightly

$504 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-Sweet-Marion-Dock-Boat-Ramp-Hot-Tub.h104523088.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/62aee6da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/2ac0ad5e_edited_fd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/w1057h775x63y0-6c79090c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/124000000/123610000/123609000/123608930/4a09493e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Tee Vee Cove is the place to be located near great golfing, fishing and food

[](https://www.expedia.com/Elloree-Hotels-The-Tee-Vee-Cove-Is-The-Place-To-Be-Located-Near-Great-Golfing.h123608930.Hotel-Information)

Elloree

$232 nightly

$258 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-The-Tee-Vee-Cove-Is-The-Place-To-Be-Located-Near-Great-Golfing.h123608930.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/38650b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/00cecc0b_edited_986a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/aff09b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/b53af47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

[](https://www.expedia.com/Beautiful-Country-Cottage-With-Ease-Of-Access-Minutes-To-I-26.h76591706.Hotel-Information)

Bowman

9.8/10

Exceptional

(32 reviews)

"Will stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert B.

$155 nightly

$172 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Beautiful-Country-Cottage-With-Ease-Of-Access-Minutes-To-I-26.h76591706.Hotel-Information)

![TV, fireplace](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/4b88cd29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Oven, stovetop](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/113f5a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/92effdbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/125000000/124490000/124483900/124483821/52ad34c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Farm Stay on 30-Acres

[](https://www.expedia.com/Summerton-Hotels-A-Private-Cozy-Cabin-In-The-Country.h124483821.Hotel-Information)

Summerton

$407 nightly

$452 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-A-Private-Cozy-Cabin-In-The-Country.h124483821.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/ec7cddf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/431a876d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/0949138a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/9b1fe174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

[](https://www.expedia.com/Summerton-Hotels-SANITIZED-Lake-Marion-Lakefront-Sandy-Beach.h19993568.Hotel-Information)

Summerton

9.6/10

Exceptional

(249 reviews)

"We had a great family retreat "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ernestine C.

$455 nightly

$505 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Summerton-Hotels-SANITIZED-Lake-Marion-Lakefront-Sandy-Beach.h19993568.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1198h1600x0y0-8fa30947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/d8b442d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1197h1600x0y0-a4a4fa86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/92a17159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful brick home w/ large porch and 3 bedrooms

[](https://www.expedia.com/Beautiful-Brick-Home-W-Large-Porch-And-3-Bedrooms.h112528151.Hotel-Information)

Bowman

9.2/10

Wonderful

(5 reviews)

"Nice and quiet property. It served us well for the weekend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mick S.

$253 nightly

$280 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Beautiful-Brick-Home-W-Large-Porch-And-3-Bedrooms.h112528151.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/43244fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/3ffc5e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/e994b052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95770000/95766400/95766315/4b83f22c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Stylish One Bedroom Apartment 

[](https://www.expedia.com/Elloree-Hotels-Spacious-Stylish-One-Bedroom-Apartment.h95766315.Hotel-Information)

Elloree

8.0/10

Very Good

(1 review)

"Very nice home! Pictures are as advertised and the home was very clean. The area surrounding the home is dilapidated, however, the home is very nice. The only two issues with the house are 1) the walls are very thin and you can hear the road noise and every step the people above take very clearly. 2) there is an issue with the municipal pipes of the town and my last night of the stay the water in the shower and bathroom sink was coming out yellow. Overall a very nice option in this small town."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joshua S.

$260 nightly

$289 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Elloree-Hotels-Spacious-Stylish-One-Bedroom-Apartment.h95766315.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&regionId=9953&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=COTTAGE)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=CONDO)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=APARTMENT)

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## Top Santee Hotel Reviews

![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg)

### Baymont by Wyndham Santee

6/10 Okay

"The location is convenient for a 95 road trip. The room is clean. The breakfast does not have any hot food, no eggs. It is not a typical basic continental breakfast for this kind of hotels and price."

[](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg)

### Tru By Hilton Santee

10/10 Excellent

"Clean lobby, nice staff."

[](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![SpringHill Suites by Marriott Orangeburg](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69_y.jpg)

### SpringHill Suites by Marriott Orangeburg

8/10 Good

"We love the Bar at the hotels and my children really enjoy the indoor pool "

[](https://expedia.com/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information)

![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg)

### Hampton Inn Santee-I-95

10/10 Excellent

"Room was great nice and clean, quiet. Nothing broken bed comfy. Breakfast was great, everything I could ask for was available. We travel with a 65 lbs dog. Plenty of safe space for the dog to do business and a little exercise "

[](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35_y.jpg)

### Tru by Hilton Orangeburg

10/10 Excellent

"Breakfast was tasty and we appreciated being able to take the dogs down to the designated area at breakfast. The evening check in attendant on 3/4/26 was great. Our room was clean."

[](https://expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information)

![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg)

### Comfort Inn & Suites Santee

8/10 Good

"The stay was good though not as good as other Comfort Inn and Suites. Room was very clean but toilet seat looked like it had come "

[](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information)

![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3_y.jpg)

### Holiday Inn Santee by IHG

8/10 Good

"Parking was easy. There are not many if any restaurants nearby. Some fast food places but I didn't explore much. My room was quiet and clean. Easy check-in and checkout. The lady at the desk was friendly. "

[](https://expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information)

![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26_y.jpg)

### Fairfield Inn by Marriott Orangeburg

8/10 Good

"We stayed here in order to visit nearby Congaree National Park. Overall it was a good stay."

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information)

![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg)

### Fairfield Inn & Suites by Marriott Santee

8/10 Good

"Lovely staff who were very helpful "

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

## Find out more about Santee

**Everything you need to know about Santee vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santee vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santee rentals**

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santee

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- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Santee ](https://expedia.com/Santee-Private-Vacation-Homes.d9953-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cottages in Santee ](https://expedia.com/Santee-Cottages.d9953-aaCottages.Travel-Guide-Accommodation)
- [Motels in Santee ](https://expedia.com/Santee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)
- [Condo Rentals in Santee ](https://expedia.com/Santee-Condos.d9953-aaCondos.Travel-Guide-Accommodation)
- [Apartments in Santee ](https://expedia.com/Santee-Apartments.d9953-aaApartments.Travel-Guide-Accommodation)
- [Cabin Rentals in Santee ](https://expedia.com/Santee-Cabins.d9953-aaCabins.Travel-Guide-Accommodation)
- [Resorts in Santee ](https://expedia.com/Santee-Resorts.d9953-aaResorts.Travel-Guide-Accommodation)
- [Aparthotels in Santee ](https://expedia.com/Santee-Apart-Hotels.d9953-aaApartHotels.Travel-Guide-Accommodation)
- [RV Parks in Santee ](https://expedia.com/Santee-RV-Parks.d9953-aaRVParks.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find vacation rentals in Santee?

### What are some of the best vacation home rentals in Santee?

### How many vacation rentals are there in Santee?

### What can I see and do in Santee?

### What are vacation rentals like in Santee?

### Expedia's Latest Trends

Hotels

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Flights

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- [Cheap Flights to Charleston](https://expedia.com/Cheap-Flights-To-Charleston.d179997.Travel-Guide-Flights)
- [Cheap Flights to Hilton Head Island](https://expedia.com/Cheap-Flights-To-Hilton-Head-Island.d601684.Travel-Guide-Flights)
- [Cheap Flights to Myrtle Beach](https://expedia.com/Cheap-Flights-To-Myrtle-Beach.d601685.Travel-Guide-Flights)

Cars

- [Car rentals in Columbia](https://expedia.com/Car-Rentals-In-Columbia.d764.Car-Rental-Guide)
- [Car rentals in Charleston](https://expedia.com/Car-Rentals-In-Charleston.d179997.Car-Rental-Guide)
- [Car rentals in Myrtle Beach](https://expedia.com/Car-Rentals-In-Myrtle-Beach.d601685.Car-Rental-Guide)
- [Car rentals in Greenville](https://expedia.com/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)

Cruises

- [Cruises from Charleston](https://expedia.com/Cruises-from-Charleston.d179997.Cruise-Departure-Port)

Activities

- [Things to do in Myrtle Beach](https://expedia.com/Things-To-Do-In-Myrtle-Beach.d601685.Travel-Guide-Activities)

Packages

- [Myrtle Beach Vacation](https://expedia.com/Myrtle-Beach.d601685.Destination-Travel-Guides)

Vacation Rentals

- [Myrtle Beach Vacation Rentals](https://expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)

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