Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (14 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
$460 nightly
The price is $511
May 23 - May 24
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (43 reviews)
"Great communication, always a great place to stay on our way to Florida. It’s only 2 miles from 95 and there are restaurants and an IGA for groceries. Thanks Mike, Paul"
United States
Paul V.
$291 nightly
The price is $323
May 18 - May 19
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (44 reviews)
"Great stay."
United States
Tim E.
$193 nightly
The price is $214
May 18 - May 19
Total with taxes and fees
Country living lake style near Santee

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (143 reviews)
"Our host was excellent and the fenced-in yard was perfect for our dog!"
United States
Michael H.
$186 nightly
The price is $206
May 18 - May 19
Total with taxes and fees
Pet friendly country cottage with large fenced-in yard & horses on property

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
9.0 out of 10, Wonderful, (29 reviews)
"Lake view and location was great. Everyone in the park was very friendly. Good diner. Perfect for us!!!!!"
United States
Elizabeth
$157 nightly
The price is $175
May 19 - May 20
Total with taxes and fees
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
$428 nightly
The price is $486
May 26 - May 27
Total with taxes and fees
Turtle Cove - Lake Living on Lake Marion

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
$121 nightly
The price is $134
May 17 - May 18
Total with taxes and fees
Bells Marina & Resort

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very Good, (16 reviews)
"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "
United States
Derrick W.
$120 nightly
The price is $133
May 18 - May 19
Total with taxes and fees
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (33 reviews)
"Will stay again."
United States
Robert B.
$147 nightly
The price is $163
May 27 - May 28
Total with taxes and fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.8 out of 10, Good, (7 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
$128 nightly
The price is $142
May 18 - May 19
Total with taxes and fees
Cabin at the lake in Rimini, SC

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (12 reviews)
"Great stay!"
United States
Hayden S.
$145 nightly
The price is $161
May 17 - May 18
Total with taxes and fees
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.

The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.
Cross
10.0 out of 10, Exceptional, (1 review)
"The time at the sweet apartment was a relief for myself and my little one The utilities were nice and clean and we felt comfortable . Thank you so much."
United States
Lesley B.
The Beehive is 19 miles from I-95, 16 miles from I-26. Fishing, hunting & more.

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
10.0 out of 10, Exceptional, (1 review)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
$194 nightly
The price is $219
May 16 - May 17
Total with taxes and fees
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
$480 nightly
The price is $533
May 17 - May 18
Total with taxes and fees
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Summerton
9.6 out of 10, Exceptional, (254 reviews)
"Could use a better cleaning service, but other than that it’s a house with plenty of room. "
United States
Megan A.
$571 nightly
The price is $634
May 21 - May 22
Total with taxes and fees
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
$165 nightly
The price is $183
May 18 - May 19
Total with taxes and fees
Modern apartment overlooking historic downtown Elloree, SC.

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
$381 nightly
The price is $423
May 28 - May 29
Total with taxes and fees
Boat House (private Cabin) - Boat House (Private Cabin)

The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
9.0 out of 10, Wonderful, (2 reviews)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
$237 nightly
The price is $263
May 16 - May 17
Total with taxes and fees
The Tee Vee Cove is the place to be located near great golfing, fishing and food
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $134 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated vacation home rental in Santee is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 8 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.