Title: Best Santee, SC Serviced Apartments for Your Vacation from $116 | Expedia.com

[Santee Travel Guide](https://expedia.com/Santee.dx9953)[Hotels in Santee](https://expedia.com/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.com/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.com/Santee.d9953.Destination-Travel-Guides)

![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee aparthotels

![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Tent | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9123f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bells Marina & Resort

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

Eutawville

8.6/10

Excellent

(87 reviews)

"Super quaint, quiet, nice little get away."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

$105 nightly

$116 total

Feb 17 - Feb 18

Total with taxes and fees

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-01&endDate=2026-03-02&regionId=9953&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=COTTAGE)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=CONDO)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America&regionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2026-05-16&d1=2026-05-16&endDate=2026-05-19&d2=2026-05-19&lodging=APART_HOTEL)

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## Top Santee Hotel Reviews

![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg)

### Hampton Inn Santee-I-95

10/10 Excellent

"staff was great and room spacious and very clean "

[](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg)

### Travelodge by Wyndham Santee

10/10 Excellent

"Front desk staff friendly and professional. Clean rooms "

[](https://expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)

![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg)

### Best Western Plus Santee Inn

10/10 Excellent

"Clean, spacious room. Comfortable bed. Quiet "

[](https://expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)

![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg)

### Tru By Hilton Santee

10/10 Excellent

"Exelent service. Friendly staff "

[](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg)

### Comfort Inn & Suites Santee

10/10 Excellent

"Place was nice and will stay there again."

[](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information)

![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg)

### Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

"The room was fine, the breakfast fair, the staff great."

[](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg)

### Baymont by Wyndham Santee

10/10 Excellent

"Friendly, knowledgeable receptionist; clean, comfortable, quiet room. I love this place."

[](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg)

### Holiday Inn Santee by IHG

10/10 Excellent

"Bed was so comfy….clean. Great staff."

[](https://expedia.com/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information)

![Quality Inn & Suites](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053_y.jpg)

### Quality Inn & Suites

10/10 Excellent

"Clean room but needs an exhaust fan in the bathroom "

[](https://expedia.com/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information)

## Find out more about Santee

## Santee Aparthotels information

| Number of reviews | 86            |
| ----------------- | ------------- |
| Accommodation     | 1 Aparthotels |
| Lowest Price      | $116          |
| Highest Price     | $116          |

## Frequently asked questions

### What can I expect from my Santee aparthotel stay?

### What is the top aparthotel for my stay in Santee?

### How many aparthotels are available in Santee?

### What are the must-see places to visit in Santee?

### What is an aparthotel?

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