Search Vacation Homes in Santee

Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Vacation Homes in Santee

Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Dining

Lake Marion Home: Kayaks, Dock, Waterfront Fun!

9.4 out of 10, Exceptional, (8)
"This property was a very nice getaway for my friend and I. We enjoyed the quite neighborhood and sitting on the back porch enjoying the early fall weather. Hope to stay again in the future. "
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Courtney House on Lake Marion
Property grounds

Courtney House on Lake Marion

10.0 out of 10, Exceptional, (95)
"My family and I had a great time staying at the Courtney House. Ms Judy and her husband were great hosts. We will definitely be coming back to stay."
Courtney House on Lake Marion
Beautiful lake home to make your family vacation extra special!
Fridge, microwave, oven, stovetop

Beautiful lake home to make your family vacation extra special!

9.0 out of 10, Wonderful, (56)
"This was an awesome stay! Home was clean and comfortable. Great hosts!"
Beautiful lake home to make your family vacation extra special!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Outdoor dining

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (34)
"We needed a place with two separate bedrooms. This property fit the bill. Perfect for our trip. Nice accommodations. Would definitely recommend this property. "
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Property grounds

Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

10.0 out of 10, Exceptional, (5)
"This property was perfect for a little lake time during spring break. It was very peaceful and family friendly. The porch was our favorite part!"
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Sweet Marion - Dock + Boat Ramp + Hot Tub!
Terrace/patio

Sweet Marion - Dock + Boat Ramp + Hot Tub!

8.8 out of 10, Excellent, (14)
"Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay."
Sweet Marion - Dock + Boat Ramp + Hot Tub!
Archie's Lake Daze Cottage
Property grounds

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (74)
"We had a great time. Clean and everything we needed and then some!! We will definitely be back"
Archie's Lake Daze Cottage
Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.2 out of 10, Wonderful, (19)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Spacious Family Home on Lake Marion w/ Boat Ramp!
Interior

Spacious Family Home on Lake Marion w/ Boat Ramp!

10.0 out of 10, Exceptional, (6)
"Awesome place. Had everything thing we needed. Comfy too."
Spacious Family Home on Lake Marion w/ Boat Ramp!
Beautiful Cottage between Lake Moultrie and Lake Marion
Smart TV, video games, DVD player, books

Beautiful Cottage between Lake Moultrie and Lake Marion

9.8 out of 10, Exceptional, (140)
"Great visit! Best house on the water in the lake area for our needs! "
Beautiful Cottage between Lake Moultrie and Lake Marion
LAKE MARION LAKE FRONT VACATION RENTAL
Terrace/patio

LAKE MARION LAKE FRONT VACATION RENTAL

9.4 out of 10, Exceptional, (89)
"Nice place and very comfortable but sparsely supplied. Also the neighborhood dogs barked constantly. Fishing was non existent. "
LAKE MARION LAKE FRONT VACATION RENTAL
Cozy & Peaceful 3 bed 2 bath On the Water
Fridge, microwave, oven, stovetop

Cozy & Peaceful 3 bed 2 bath On the Water

10.0 out of 10, Exceptional, (33)
"We have ateyed twice now and I have been impressed both times. The place is alway clean and comfortable. Im sure we will be back!"
Cozy & Peaceful 3 bed 2 bath On the Water
Lakefront Retreat on Lake Marion
Outdoor dining

Lakefront Retreat on Lake Marion

9.4 out of 10, Exceptional, (30)
"Right on the water Cabin had plenty of room a great location"
Lakefront Retreat on Lake Marion
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Exterior

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

10.0 out of 10, Exceptional, (39)
"Very nice place to stay. We had everything we needed for the comforts of home. "
$281 nightly
The price is $312
Aug 5 - Aug 6
Total includes taxes and fees
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Lake Marion Lakehouse with 180° lake view
Exterior

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (67)
"I would stay here again. Great location."
Lake Marion Lakehouse with 180° lake view
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Fridge, microwave, oven, stovetop

6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates

7.2 out of 10, Good, (11)
"Wonderful place to stay with a group. Rustic but has everything you need. Very comfortable. "
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Lake Marion Getaway!
TV

Lake Marion Getaway!

2.0 star property
9.2 out of 10, Wonderful, (38)
"Very nice host. Place was clean and had plenty of room. Family enjoyed their stay. "
Lake Marion Getaway!
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Property grounds

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

9.8 out of 10, Exceptional, (169)
"This property was great for our needs and I would recommend it to anyone looking for a getaway or event which needs more capacity for guests."
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Interior

Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion

2.0 star property
9.6 out of 10, Exceptional, (4)
"Wonderful classic lake weekend! House had everything we needed! "
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Private Dock + Pool Table: Lake Marion Getaway
Dining

Private Dock + Pool Table: Lake Marion Getaway

9.0 out of 10, Wonderful, (2)
"Great property, we will return and highly recommended."
Private Dock + Pool Table: Lake Marion Getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
"Stay here for a night on the way to FL. The property is right o"
Joseph 1-night trip
Posted 23 hours ago
Baymont by Wyndham Santee