Title: 10 Best Motels in Santee: Find Cheap Motels in Santee, SC 2026 - Expedia.com [Santee Travel Guide](https://expedia.com/Santee.dx9953)[Hotels in Santee](https://expedia.com/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.com/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.com/Santee.d9953.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=9953&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santee motels ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (446 reviews) "The beds are super comfy. I liked how quiet it was in the room and the staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy $75 nightly $83 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/b034ff09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/efa2345e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (176 reviews) "The room was very clean , the price was very reasonable and the staff was very helpful. I'll definitely stay again. And recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Precious $70 nightly $76 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/d4b79aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Bathroom sink](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/13cfcb42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very Good (1,006 reviews) "Property was easy to find, room was clean, restaurants close, front desk staff was super friendly, comfortable bed. All good. Would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kawahna $71 nightly $79 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/47b4af62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/cef510a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/5bdd7f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Private kitchenette | Fridge, microwave](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/60d574cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Lodge 601 [](https://www.expedia.com/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) Orangeburg 6.0/10 (2 reviews) "The room smelled. The tub leaked water all over the floor and it didn’t work. There were dead and living bugs on the floor. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward $76 nightly $84 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/c853f767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/ccb93e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/8ed2f402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/88261caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Manning [](https://www.expedia.com/Sumter-Hotels-Super-8-By-Wyndham-Manning.h317245.Hotel-Information) Manning 6.4/10 (395 reviews) "The staff was friendly and the room clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) dennis $60 nightly $67 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Super-8-By-Wyndham-Manning.h317245.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/7655013c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/ca4e9299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/b4a7d12b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Orangeburg 6.8/10 (933 reviews) "Easy check in and out, good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa $58 nightly $64 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=9953&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Motels.d9953-aaMotels.Travel-Guide-Accommodation) ## Top Santee Hotel Reviews ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "The stay was wonderful " [](https://expedia.com/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg) ### Comfort Inn & Suites Santee 2/10 Terrible "We call it the discomfort inn. Never again. I couldn’t book the two places we frequent so we chose here and it’s a no in so many ways. I am now in Savannah for the same price with hotel.com in a beautiful hotel.. Clean your windows, put in room thermostats, add a ceiling fan for air circulation and update your rooms . It’s old and not kept. Sorry but it’s truth." [](https://expedia.com/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "This was a stand out hotel. If you’re traveling through the area this is the place to stay. " [](https://expedia.com/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Love staying here. My only complaint is that the room floor has not always been thoroughly cleaned/mopped. Not visibly dirty but my socks show evidence of the floor not being totally clean. We stay here 2-4 times per year. Breakfast is good and staff are always very nice. Love that they allow pets even if there is a fee. " [](https://expedia.com/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Very nice hotel. Great price too!" [](https://expedia.com/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 2/10 Terrible "The room was dirty, smelly and bugs. Left room within a hour. Asked for a refund which we haven’t received. Booked this room because it said it had a rating of 8\. Can’t imagine how it got this rating.Very disappointing!!!" [](https://expedia.com/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "This property is AMAZING!! The rooms are beautiful and well maintained. The breakfast (included) was exceptional as were the ladies preparing it and maintaining the area for cleanliness. The entire staff were helpful, polite and professional. We recommend it highly!! " [](https://expedia.com/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "N/a" [](https://expedia.com/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![SureStay Hotel by Best Western Manning](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/27faffbf_y.jpg) ### SureStay Hotel by Best Western Manning 10/10 Excellent "Very Pleasant " [](https://expedia.com/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ## Find out more about Santee ## Santee Motels information | Number of reviews | 2,956 | | ----------------- | --------- | | Accommodation | 11 Motels | | Lowest Price | $64 | | Highest Price | $84 | ## Frequently asked questions ### What are the best Santee motels, based on reviews? ### What is the nightly rate for a motel in Santee? ### Is it better to stay in a Santee motel or hotel? ## Explore a world of travel with Expedia - 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