Santee Vacations from $388

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Your Santee Vacation

Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action!

The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
Seven Oaks
Price was $542, price is now $388 per person
$388
per person
Feb 14 - Feb 19
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
16.4/10 Exceptional! (1,005 reviews)
Very clean room and spacious.

Reviewed on Nov 21, 2025

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
Downtown Columbia
Price was $759, price is now $533 per person
$533
per person
Feb 14 - Feb 19
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
18.8/10 Exceptional! (1,003 reviews)
Maybe update bathrooms a little, wallpaper was peeling, same with paint in bathrooms. Lamp was broken, there was a lingering smell of cleaning product, shower could use a better deep cleaning.

Reviewed on Nov 18, 2025

The Lantern Columbia

The Lantern Columbia

3 out of 5
Downtown Columbia
Price was $843, price is now $620 per person
$620
per person
Jan 7 - Jan 14
found 1 day ago
Roundtrip non-stop flight included
El Paso (ELP) to Columbia (CAE)
No reviews
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
Downtown Columbia
Price was $724, price is now $540 per person
$540
per person
Feb 14 - Feb 19
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
17.6/10 Exceptional! (1,002 reviews)
Clean room and friendly staff. The thermostat in t

Reviewed on Nov 19, 2025

Hilton Garden Inn Columbia Downtown, SC

Hilton Garden Inn Columbia Downtown, SC

3 out of 5
Downtown Columbia
Price was $609, price is now $460 per person
$460
per person
Jan 23 - Jan 28
found 5 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
16/10 Exceptional! (427 reviews)
Very friendly clerk at checkin, room was nice. Great location, walkable to restaurants and Township Auditorium. The shower gel was empty but not a big deal. The most disappointing thing is that they charged $17 for a breakfast buffet.

Reviewed on Nov 7, 2025

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Discover the most popular places to visit in Santee

Santee State Park

4/5(43 reviews)

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee State Park

Santee Cooper Country Club

4/5(12 reviews)

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

Santee National Golf Club

3.5/5(19 reviews)

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

Santee Hotel Deals

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Dec 7 to Dec 8
$106 total
Dec 7 - Dec 8
Total with taxes and fees
9/10 Wonderful! (602 reviews)
Staff was very helpful

Reviewed on Nov 17, 2025

Tru By Hilton Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Nov 24 to Nov 25
$89 total
Nov 24 - Nov 25
Total with taxes and fees
7.8/10 Good! (1,394 reviews)
Front desk clerk at check in was super nice and friendly. Gave me plates after hours.

Reviewed on Nov 18, 2025

Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $129 total per night from Dec 7 to Dec 8
$129 total
Dec 7 - Dec 8
Total with taxes and fees
9.8/10 Exceptional! (1,003 reviews)
Everything was great

Reviewed on Nov 15, 2025

Fairfield Inn & Suites by Marriott Santee
See all 307 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

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Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals from $388 on Expedia, you'll be surprised at how little a vacation to Santee costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
If you're hoping to snag a cheap Santee vacation package, consider visiting in January, September and October. You're likely to find better prices on accommodations and flights during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Usually, a few days to a week will give you time to hit all the leading attractions and explore some hidden treasures along the way.
Is it worth booking a vacation package to Santee?
It's no wonder a Santee vacation is on the to-do list of many travelers. Major attractions like Santee State Park are just the beginning of things to see and do here.
How to find the best Santee package deals?
Use Expedia's handy filters to help you find some fabulous Santee package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Santee package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking stays and flights individually. Better still, you can customize your Santee trip to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santee trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.