An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Lodges in Santee

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

1. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (1,007 reviews)
"Nice little hotel conveniently located."
United States
Armando
$100 nightly
The price is $111
Nov 22 - Nov 23
Total with taxes and fees
Tru By Hilton Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
"Nice place to stay"
United States
sandra
$123 nightly
The price is $137
Nov 25 - Nov 26
Total with taxes and fees
Hampton Inn Santee-I-95
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

3. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,507 reviews)
"Good one night stay Staff was wonderful"
United States
Thomas
$80 nightly
The price is $89
Nov 3 - Nov 4
Total with taxes and fees
Baymont by Wyndham Santee
A patio area with wicker furniture, a stone fire pit, and outdoor seating.

4. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,003 reviews)
"Convenient location close to the highway and restaurants. Large parking , excellent breakfast and comfortable room."
United States
Victor
$139 nightly
The price is $154
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
A hotel entrance with a sign reading "Best Western PLISS."

5. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
"Nice location and very convenient parking, Breakfast was very good."
United States
Johnny
$119 nightly
The price is $132
Nov 22 - Nov 23
Total with taxes and fees
Best Western Plus Santee Inn
A water park with a pool, slides, and umbrellas.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"Great staff and really clean room!"
United States
Traci
$110 nightly
The price is $122
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Santee by IHG
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,005 reviews)
"Great hotel"
United States
Alexis
$99 nightly
The price is $110
Nov 29 - Nov 30
Total with taxes and fees
Comfort Inn & Suites Santee
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (787 reviews)
"Extremely good value for money, room was clean, tidy and very well appointed. Will absolutely come here again."
United States
Robert
$64 nightly
The price is $71
Nov 3 - Nov 4
Total with taxes and fees
Travelodge by Wyndham Santee
A dining area with multiple tables and chairs, a ceiling fan, and large windows.

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (477 reviews)
"An older fecility but certainly well maintained. Loved Mr. Patel!"
United States
William
$64 nightly
The price is $71
Nov 9 - Nov 10
Total with taxes and fees
Super 8 by Wyndham Santee/I-95
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
5.8 out of 10, (613 reviews)
"Clean room and nice staff"
United States
Louis
$59 nightly
The price is $65
Nov 23 - Nov 24
Total with taxes and fees
Quality Inn & Suites Santee I-95
A cabin with a porch, surrounded by trees and a body of water.

11. Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (668 reviews)
"Everything was adequate or good."
United States
Sharyn
$63 nightly
The price is $70
Nov 8 - Nov 9
Total with taxes and fees
Red Roof Inn Santee
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

12. Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (317 reviews)
"Pretty nice and clean with a comfortable bed at a great rate."
United States
Arthur
$68 nightly
The price is $75
Nov 23 - Nov 24
Total with taxes and fees
Econo Lodge Santee
A spacious living room with a large sofa, two coffee tables, and a potted plant.

13. Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (47 reviews)
"Comfortable home with fenced in yard for dogs is a plus. The house had everything needed for a stay. Furniture was comfy. House is an hour drive from congaree NP. Many opportunities nearby to connect with nature."
United States
Jessica C.
$267 nightly
The price is $297
Nov 3 - Nov 4
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
A covered patio with outdoor furniture, a view of a lake, and a sunset.

14. LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
9.0 out of 10, Wonderful, (8 reviews)
"We had a wonderful stay. Couldn't have asked for better location. It was beautiful, close to everything and perfect for our family."
United States
Michelle H.
$417 nightly
The price is $463
Nov 3 - Nov 4
Total with taxes and fees
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
A lakeside park with picnic tables and a wooden bridge over the water.

15. Lake Marion Condo, Boat Slip Included, Pet Friendly

Lake Marion Condo, Boat Slip Included, Pet Friendly
Santee
10.0 out of 10, Exceptional, (1 review)
"My husband, son and I booked a relatively last-minute weekend trip. Gabriel was great, and fast about answering my questions. The unit was easy to find and gain entry to. It is very clean, quiet, and accessible to the water; a very short walk to the on-prem docks and the covered porch is very nice. We had an enjoyable stay and liked the area."
United States
Katie A.
$296 nightly
The price is $329
Nov 3 - Nov 4
Total with taxes and fees
Lake Marion Condo, Boat Slip Included, Pet Friendly
A wicker outdoor seating area with cushioned chairs and a matching ottoman on a porch.

16. Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (16 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
$436 nightly
The price is $484
Nov 15 - Nov 16
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
A hotel room with two beds, a desk, a chair, and a view of the hallway.

17. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (597 reviews)
"The price rate was great"
United States
Stevenson
$86 nightly
The price is $96
Nov 30 - Dec 1
Total with taxes and fees
Ramada by Wyndham Santee I-95
A hotel lobby with a reception desk, a staircase, and signs for restrooms and the office.

18. Ashburn Inn Manning I 95

Ashburn Inn Manning I 95
2.0 star property
Manning
$69 nightly
The price is $77
Nov 3 - Nov 4
Total with taxes and fees
Ashburn Inn Manning I 95
A tent with a view of a lake and boats, a wooden chair, and a potted plant.

19. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (103 reviews)
"Love it"
United States
Mark
$74 nightly
The price is $82
Nov 3 - Nov 4
Total with taxes and fees
Bells Marina & Resort
A covered outdoor seating area with a view of a dock and boats, wooden furniture, and string lights.

20. Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.
Summerton
8.8 out of 10, Excellent, (41 reviews)
"Great place to stay on the lake! "
United States
Troy S.
$141 nightly
The price is $157
Nov 3 - Nov 4
Total with taxes and fees
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

Tru By Hilton Santee

Tru By Hilton Santee

10/10 Excellent
"First Time Staying at Tru by Hilton! This was our first time staying at Tru by Hilton. We stopped overnight on our way to Florida, and I have to say, we had a great experience! We were greeted with a warm welcome by the friendly staff, who even gave us a few recommendations on places to eat nearby. My first impression when walking in was how CLEAN the hotel smelled!!! I’ll admit, I was a little skeptical since they allow furry family members. Sometimes pet-friendly hotels have that certain smell, but not this one! It honestly smelled brand new! The bed was extremely comfortable, which was much needed after being on the road. I also really appreciated their quiet hours! This is so important because most people stopping overnight are just looking to get some SLEEP! I didn’t hear any noise from inside the hotel, just a little highway traffic, which didn’t bother me at all. That was definitely a plus! Breakfast was also a nice bonus before getting back on the road. Overall, we really enjoyed our stay! Clean hotel, friendly staff, comfortable beds, and a peaceful night’s sleep. What more could you ask for? Definitely recommend, and we would absolutely stay here again!"
Paula 1-night trip
Posted 20 hours ago
Tru By Hilton Santee

Find out more about Santee

Santee Lodges information

Number of reviews
4,537
Accommodation
1 Lodges
Lowest Price
$65
Highest Price
$484

Explore a world of travel with Expedia