Science Hill Vacations from $378

Book a Hotel + Flight or Car together to unlock savings

Your Science Hill Vacation

Excellent adventures await when you lock in a vacation package to Science Hill. Whether you're a history buff, foodie or just a traveler who loves experiencing new places, there's something for everyone in this awesome city. SomerSplash and Cave Hill Vineyard are a couple of the top attractions to tour during your trip to Science Hill. Expedia will help you escape your routine. Tailor your vacation to Science Hill to suit your travel style, whatever that may be!

The Latest Science Hill vacation packages

Price found within the past 48 hours. Click for updated prices.
Clarion Hotel Conference Center Lexington North

Clarion Hotel Conference Center Lexington North

3 out of 5
Price was $437, price is now $378 per person
$378
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Lexington (LEX)
7.6/10 Good! (1,002 reviews)
Great location. Fabulous attached restaurant. Breakfast was hot, clean, lovely. Hotel is under renovation. But staff was wonderful to ensure I got an updated, appropriate to my needs (quiet, room darkening). Would definitely come again

Reviewed on Feb 26, 2026

The Aldenberg Hotel

The Aldenberg Hotel

2 out of 5
Price was $695, price is now $510 per person
$510
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Lexington (LEX)
9.6/10 Exceptional! (5 reviews)
Room was clean. Staff was friendly and professional. Good location, walkable to restaurants and shops.

Reviewed on Feb 16, 2026

21c Museum Hotel Lexington

21c Museum Hotel Lexington

4 out of 5
Downtown Lexington
Price was $634, price is now $482 per person
$482
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Lexington (LEX)
8.8/10 Excellent! (1,002 reviews)
This hotel is in a great location, walkable to UK, restaurants, shops. The room was very clean, the bathroom is huge. I loved having the robes. Overall great experience, we will definitely stay again. The bar/lounge area looked lovely, unfortunately we didn’t have the time to enjoy a drink there but it had a nice vibe.

Reviewed on Mar 2, 2026

DoubleTree Suites by Hilton Hotel Lexington

DoubleTree Suites by Hilton Hotel Lexington

4 out of 5
Price was $499, price is now $410 per person
$410
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Lexington (LEX)
8.8/10 Excellent! (1,002 reviews)
Everything was nice.

Reviewed on Feb 23, 2026

Capital Plaza Hotel

Capital Plaza Hotel

3 out of 5
Price was $479, price is now $396 per person
$396
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to Lexington (LEX)
8.2/10 Very Good! (1,040 reviews)
Very nice, the only reason for the lower score is that the hotel was under construction and some things weren't available because of that. My biggest disappointment was that nothing in the hotel was open while I was there on a Sunday night, the lounge and restaurant were both closed. The downtown area is within walking distance, but I did not feel safe walking there alone at night.

Reviewed on Mar 3, 2026

Don't see what you're looking for?
See all available trips from Columbus to Science Hill
View all trips

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Science Hill Hotel Deals

Hampton Inn Somerset

Hampton Inn Somerset

2.5 out of 5
4141 S Highway 27 Somerset KY
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $123 total per night from Mar 22 to Mar 23
$123 total
Mar 22 - Mar 23
Total with taxes and fees
9.4/10 Exceptional! (445 reviews)
Staff was very welcoming and the room was very clean.

Reviewed on Feb 23, 2026

Hampton Inn Somerset
Courtyard by Marriott Somerset

Courtyard by Marriott Somerset

3 out of 5
2254 South Highway 27 Somerset KY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $145 total per night from Mar 8 to Mar 9
$145 total
Mar 8 - Mar 9
Total with taxes and fees
9/10 Wonderful! (570 reviews)
Our room was clean and comfy. Front desk was nice, low-key, welcoming.

Reviewed on Feb 25, 2026

Courtyard by Marriott Somerset
Days Inn by Wyndham Renfro Valley Mount Vernon

Days Inn by Wyndham Renfro Valley Mount Vernon

2 out of 5
1630 Richmond St Mount Vernon KY
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $68 total per night from Mar 15 to Mar 16
$68 total
Mar 15 - Mar 16
Total with taxes and fees
7.6/10 Good! (778 reviews)
Staff great. I was only there long enough to sleep but it appeared clean.

Reviewed on Feb 25, 2026

Days Inn by Wyndham Renfro Valley Mount Vernon
See all 560 properties in Science Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Science Hill Vacation Packages

Science Hill Essential Information

Language
English
Currency
U.S dollars
Population
700
Top Sights
SomerSplash, Cedar Creek Vineyards and Sinking Valley Vineyard and Winery

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Science Hill vacation package cost?
You'll find cheap prices from $378 on Expedia for your Science Hill getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Science Hill costs.
What are the cheapest months to go to Science Hill?
You can usually find lower rates and greater availability in February, November and December. Explore our cheap Science Hill vacation packages and you could score some great off-season discounts.
How many days is enough for Science Hill?
The ideal duration of your Science Hill vacation depends on what you'd like to do. Usually, a few days to a week will give you plenty of time to visit all the top sights and explore some hidden spots along the way.
How to find the best Science Hill package deals?
Start your search for a Science Hill package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the ideal Science Hill package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Science Hill getaway off to a flying start.
Is it cheaper to book a Science Hill vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging hotels and flights individually. Better still, you can tailor your Science Hill trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Science Hill?
Enjoy incredible bargains by booking your flights early with Expedia. If being spontaneous is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Science Hill escape.
Does Expedia offer Book Now, Pay Later Science Hill vacation packages?
Set off on your perfect escape to Science Hill with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait for your next payday — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's a breeze to stay on budget and snap up cheap deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.