Cheap Flights from Mexico City (MEX) to Santiago del Estero (SDE)

Popular airlines from Benito Juarez International Airport (MEX) to Santiago del Estero (SDE-Vicecomodoro Angel de la Paz Aragones)

Frequently asked questions

How much is a flight from Mexico Airport to SDE?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price listed for a round-trip flight between Mexico Airport and Vicecomodoro Angel de la Paz Aragones Airport (SDE) was . Great fares don't hang around forever, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from MEX to SDE?
We understand that your situation can change unexpectedly, so we've made it as simple as possible for you to cancel your flight online. Just visit the Customer Service Portal and follow the instructions.
How do I find cheap flights from Mexico Airport to SDE that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for MEX to Santiago del Estero Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Mexico City Intl. Airport (MEX) to Santiago del Estero Airport?
Mexico City to Santiago del Estero is around 4040 mi, so get ready to spend a while in the air. Don't forget to pack all the essentials, from your headphones to your hoodie. Take a few snacks to nibble on throughout your journey too.
Which airlines fly direct from Mexico City Intl. Airport (MEX) to Santiago del Estero Airport?
Flying nonstop between MEX and Santiago del Estero Airport isn't possible at present. However, you'll still be able to book a flight to Santiago del Estero with at least one stop.
Are MEX to Vicecomodoro Angel de la Paz Aragones Airport (SDE) flight tickets cheaper when they're purchased at the last minute?
Booking last minute from Mexico City Intl. Airport (MEX) to SDE can be hit-or-miss. You may be able to score a bargain, but you could also miss out completely! If you'd rather play it safe and start your travel planning early, Expedia compares flight deals up to a year in advance. Just bear in mind that not all airlines publish their prices so far in advance. Our advice? Check back often as updates are made regularly.

Travel information

Origin airport
Mexico City Intl.
Destination airport
Vicecomodoro Angel de la Paz Aragones
Distance
4004 mi

Book with confidence

Mexico City to Santiago del Estero Flights

The cheapest times to fly from Mexico City to Santiago del Estero

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexico City to Santiago del Estero are during the month of . You can find some of the cheapest flights from Mexico City to Santiago del Estero with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexico City to Santiago del Estero

Sunday is one of the best days to book for cheap flights from Mexico City to Santiago del Estero: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexico City to Santiago del Estero

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexico City to Santiago del Estero in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexico City to Santiago del Estero flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexico City to Santiago del Estero airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mexico City to Santiago del Estero Flights
*Available to One Key members.