$436 Cheap Flights from Panama City (PTY) to Milan (MXP)

View $436 flight on Wed, Apr 22, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Milan Malpensa Airport (MXP)

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Cheap Flights from Panama City to Milan (PTY-MXP)

Prices were available within the past 7 days and start at $436 for one-way flights and $714 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Sun, Apr 19 - Sun, May 3
PTY
Panama City
MXP
Milan
$714 Roundtrip, found 6 days ago
$714
Roundtrip
found 6 days ago
Select Air Europa flight, departing Sun, Apr 19 from Panama City to Milan, returning Sun, May 3, priced at $714 found 6 days ago
Air Europa
Sun, Apr 19 - Sat, May 2
PTY
Panama City
MXP
Milan
$725 Roundtrip, found 6 days ago
$725
Roundtrip
found 6 days ago
Select Air Europa flight, departing Sun, Apr 19 from Panama City to Milan, returning Sat, May 2, priced at $725 found 6 days ago
Air Europa
Wed, Apr 29 - Sat, May 16
PTY
Panama City
MXP
Milan
$730 Roundtrip, found 6 days ago
$730
Roundtrip
found 6 days ago
Select Air Europa flight, departing Wed, Apr 29 from Panama City to Milan, returning Sat, May 16, priced at $730 found 6 days ago
Air Europa
Sun, Apr 26 - Mon, May 11
PTY
Panama City
MXP
Milan
$739 Roundtrip, found 6 days ago
$739
Roundtrip
found 6 days ago
Select Air Europa flight, departing Sun, Apr 26 from Panama City to Milan, returning Mon, May 11, priced at $739 found 6 days ago
Air Europa
Wed, Apr 29 - Thu, May 21
PTY
Panama City
MXP
Milan
$742 Roundtrip, found 6 days ago
$742
Roundtrip
found 6 days ago
Select Air Europa flight, departing Wed, Apr 29 from Panama City to Milan, returning Thu, May 21, priced at $742 found 6 days ago
Air Europa
Mon, May 11 - Tue, May 26
PTY
Panama City
MXP
Milan
$749 Roundtrip, found 1 day ago
$749
Roundtrip
found 1 day ago
Select Air Europa flight, departing Mon, May 11 from Panama City to Milan, returning Tue, May 26, priced at $749 found 1 day ago
Turkish Airlines
Mon, Mar 9 - Mon, Mar 23
PTY
Panama City
MXP
Milan
$759 Roundtrip, found 6 days ago
$759
Roundtrip
found 6 days ago
Select Turkish Airlines flight, departing Mon, Mar 9 from Panama City to Milan, returning Mon, Mar 23, priced at $759 found 6 days ago
Air France
Sat, Feb 21 - Fri, Mar 6
PTY
Panama City
MXP
Milan
$860 Roundtrip, found 1 day ago
$860
Roundtrip
found 1 day ago
Select Air France flight, departing Sat, Feb 21 from Panama City to Milan, returning Fri, Mar 6, priced at $860 found 1 day ago
KLM
Tue, Feb 24 - Tue, Mar 3
PTY
Panama City
MXP
Milan
$932 Roundtrip, found 6 days ago
$932
Roundtrip
found 6 days ago
Select KLM flight, departing Tue, Feb 24 from Panama City to Milan, returning Tue, Mar 3, priced at $932 found 6 days ago
Iberia
Wed, Feb 25 - Sun, Mar 8
PTY
Panama City
MXP
Milan
$989 Roundtrip, found 1 day ago
$989
Roundtrip
found 1 day ago
Select Iberia flight, departing Wed, Feb 25 from Panama City to Milan, returning Sun, Mar 8, priced at $989 found 1 day ago

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Alternative airports near Milan

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Malpensa Intl. MXP. Cheapest option available. Average driving time to city center is 38 minutes. Flights from $863
MXP
Malpensa Intl.
Cheapest
Average driving time to city center38 min
Flights from $863

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP) cost?
Get a cheap one-way flight from $436 or cheap return flight from $714 from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP)?
April is the most affordable month to fly from PTY to MXP. Traveling during quieter months is often the key to better flight prices.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP)?
To find the cheapest airline flying from PTY to MXP, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP)?
You'll need to catch a flight with a layover when traveling from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PTY to MXP?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP)?
To land at Malpensa Intl. Airport (MXP) on schedule, choose a flight that leaves from Tocumen Intl. Airport (PTY) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP) last-minute?
Waiting until right before your break to book a ticket from PTY to MXP generally means paying more. While it's possible to find some last-minute offers, there's no guarantee. Be flexible with your itinerary to boost your chances of getting a bargain.
Is it cheaper to book a PTY to MXP flight and hotel package?
Booking a PTY to MXP flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Malpensa Intl. Airport (MXP)?
In most instances, you can modify or cancel your PTY to MXP flight. However, there may be additional fees, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you need more information, go to our Customer Service portal.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Malpensa Intl.
Airlines serving
Air Europa, Air France, American Airlines, Condor, Delta, Iberia, KLM, Lufthansa, Turkish Airlines, United
Roundtrip price
$714
Distance
5679 mi

Book with confidence

Panama City to Milan Flights

The cheapest times to fly from Panama City to Milan

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Milan are during the month of April. You can find some of the cheapest flights from Panama City to Milan with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Milan

Sunday is one of the best days to book for cheap flights from Panama City to Milan: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Milan

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Milan in 2026. You can also book with separate airlines for your outbound and return journeys, from $436 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Milan flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Milan airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Milan Flights

*Flight schedules are subject to change.

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