$261 Cheap Flights from Santo Domingo (SDQ) to San Francisco (SFO)

View $261 flight on Thu, Dec 4, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Santo Domingo to San Francisco (SDQ-SFO)

Prices were available within the past 7 days and start at $261 for one-way flights and $467 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Thu, Dec 11 - Wed, Dec 31
SDQ
Santo Domingo
SFO
San Francisco
$467 Roundtrip, found 22 hours ago
$467
Roundtrip
found 22 hours ago
Select JetBlue Airways flight, departing Thu, Dec 11 from Santo Domingo to San Francisco, returning Wed, Dec 31, priced at $467 found 22 hours ago
Copa
Thu, Apr 2 - Mon, Apr 13
SDQ
Santo Domingo
SFO
San Francisco
$468 Roundtrip, found 2 days ago
$468
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Apr 2 from Santo Domingo to San Francisco, returning Mon, Apr 13, priced at $468 found 2 days ago
JetBlue Airways
Thu, Dec 11 - Wed, Jan 7
SDQ
Santo Domingo
SFO
San Francisco
$475 Roundtrip, found 4 hours ago
$475
Roundtrip
found 4 hours ago
Select JetBlue Airways flight, departing Thu, Dec 11 from Santo Domingo to San Francisco, returning Wed, Jan 7, priced at $475 found 4 hours ago
JetBlue Airways
Sat, Dec 13 - Wed, Dec 31
SDQ
Santo Domingo
SFO
San Francisco
$479 Roundtrip, found 22 hours ago
$479
Roundtrip
found 22 hours ago
Select JetBlue Airways flight, departing Sat, Dec 13 from Santo Domingo to San Francisco, returning Wed, Dec 31, priced at $479 found 22 hours ago
JetBlue Airways
Thu, Dec 11 - Wed, Jan 7
SDQ
Santo Domingo
SFO
San Francisco
$480 Roundtrip, found 4 hours ago
$480
Roundtrip
found 4 hours ago
Select JetBlue Airways flight, departing Thu, Dec 11 from Santo Domingo to San Francisco, returning Wed, Jan 7, priced at $480 found 4 hours ago
JetBlue Airways
Sat, Nov 15 - Sun, Dec 7
SDQ
Santo Domingo
SFO
San Francisco
$481 Roundtrip, found 3 hours ago
$481
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Sat, Nov 15 from Santo Domingo to San Francisco, returning Sun, Dec 7, priced at $481 found 3 hours ago
JetBlue Airways
Tue, Dec 9 - Thu, Jan 8
SDQ
Santo Domingo
SFO
San Francisco
$484 Roundtrip, found 2 days ago
$484
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Dec 9 from Santo Domingo to San Francisco, returning Thu, Jan 8, priced at $484 found 2 days ago
Aeromexico
Mon, Feb 2 - Sat, Feb 14
SDQ
Santo Domingo
SFO
San Francisco
$656 Roundtrip, found 2 days ago
$656
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Mon, Feb 2 from Santo Domingo to San Francisco, returning Sat, Feb 14, priced at $656 found 2 days ago
American Airlines
Thu, Dec 11 - Wed, Jan 7
SDQ
Santo Domingo
SFO
San Francisco
$693 Roundtrip, found 4 hours ago
$693
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Dec 11 from Santo Domingo to San Francisco, returning Wed, Jan 7, priced at $693 found 4 hours ago
Delta
Thu, Dec 11 - Wed, Jan 7
SDQ
Santo Domingo
SFO
San Francisco
$693 Roundtrip, found 4 hours ago
$693
Roundtrip
found 4 hours ago
Select Delta flight, departing Thu, Dec 11 from Santo Domingo to San Francisco, returning Wed, Jan 7, priced at $693 found 4 hours ago

Find the cheapest month to fly from Santo Domingo (SDQ) to San Francisco (SFO)

October is typically the cheapest month to fly

From $448 - $947 per traveler.

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $818
SFO
San Francisco Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $818

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO) cost?
Get a cheap one-way flight from $261 or cheap return flight from $467 from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)?
The cheapest month to fly from SDQ to SFO is December, when there's less demand. Off-peak season is often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from SDQ to SFO. Then, sort your results by "Price (lowest to highest)" to snag the best deal available.
How many flights per day from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)?
There aren't any daily direct flights departing from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from SDQ to SFO?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)?
To land at San Francisco Intl. Airport (SFO) without delays, select a flight that leaves from Las Americas Intl. Airport (SDQ) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO) last-minute?
Holding off until just before your trip to book a flight from SDQ to SFO often results in higher prices. Although you may find some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of landing a bargain.
Is it cheaper to book a SDQ to SFO flight and hotel package?
Compared with arranging flights and hotels separately, booking a SDQ to SFO flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place takes the hassle out of travel planning. Just secure your flights and select from our extensive range of stays, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to San Francisco Intl. Airport (SFO)?
If you reserved your SDQ to SFO flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

Travel information

Origin airport
Las Americas Intl.
Destination airport
San Francisco Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, JetBlue Airways, United, avianca
Roundtrip price
$466
Distance
3426 mi

Book with confidence

Santo Domingo to San Francisco Flights

The cheapest times to fly from Santo Domingo to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to San Francisco are during the month of December. You can find some of the cheapest flights from Santo Domingo to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to San Francisco

Sunday is one of the best days to book for cheap flights from Santo Domingo to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $261 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to San Francisco Flights

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