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See what makes Panama epic

From its pristine beaches and wild rainforest to its vibrant city streets, Panama promises an adventure you’ll never forget.

So whether you’re looking to soak up some one-of-a-kind culture, get your pulse pounding in the great outdoors, take a trek through the desert, or hop through the islands of Bocas del Toro, you’ll find it in Panama.

So come to where the North meets the South and the old and new mingle – buckle up for Panama.

Select offers from Copa Airlines

Hotel Riu Plaza Panama

Save up to 35% + free breakfast + free Wi-Fi *Terms may apply

In the heart of the financial district, Riu Plaza Panama has the best facilities for those traveling on business, and, at the same time, meets the needs of leisure travelers. Book now and enjoy an exceptional landing spot for your next trip to Panama.

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JW Marriott Panama

Prepay rate – 10% off BAR with a 14 days before arrival advanced booking.

JW Marriott Panama offers an urban getaway. Discover our infinity pools overlooking the majestic Panamanian Bay and rooms which all feature large balconies where you can relax. Treat yourself to our locally inspired gastronomy while enjoying our selection of dishes in one of our three restaurants and bars, each one with a unique soul.

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W Panama

Save up to 20% in food and drink + breakfast included *Terms may apply

Remixed with bold design and vibrant colors, W Panama is the perfect destination no matter the reason for your next trip. Connect to the local scene at La Cajita or delight on local flavors at Moró Restaurant. Take a dive at our WET Deck for a splash of fun or detox at AWAY® Spa for a refreshing experience. Whatever you choose, whenever you choose it, live it up at W Panama.

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Bern Hotels

It's easy to plan and book your vacation y staying at one of the 8 properties of Bern Hotels in Panama. Choose from one of the 8 accommodation options ranging from beach resort, city hotel, airport hotel to rainforest reserve. The hotels are Westin Playa Bonita, InterContinental Miramar, Crowne Plaza Airport, Crowne Plaza Panamá, Holiday Inn City of Knowledge, Le Méridien, Gamboa Rainforest Reserve and The Westin Panama.

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Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Avenida Aquilino de La Guardia, Bella Vista, Panama City, Panama
$200 nightly
The price is $220 total per night from Sep 21 to Sep 22
$220 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
Bristol Panama, a Registry Collection Hotel
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
$134 nightly
The price is $148 total per night from Sep 7 to Sep 8
$148 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Marriott Panama Hotel
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Santa Maria Boulevard, Panama City
$221 nightly
The price is $243 total per night from Sep 14 to Sep 15
$243 total
Sep 14 - Sep 15
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Save an average of 15% on thousands of hotels when you're signed in
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

4 out of 5
CALLE RAMON H JURADO EDIFICO P, Panama City
$144 nightly
The price is $158 total per night from Sep 20 to Sep 21
$158 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Residence Inn by Marriott Panama City
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo, Panama City, Panama
$162 nightly
The price is $178 total per night from Sep 1 to Sep 2
$178 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
Central Hotel Panama Casco Viejo
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
$116 nightly
The price is $128 total per night from Sep 7 to Sep 8
$128 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
$87 nightly
The price is $96 total per night from Sep 10 to Sep 11
$96 total
Sep 10 - Sep 11
Total with taxes and fees
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Novotel Panama City
 Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115, Carretera Interamericana - Penonome, Rio Hato, Cocle
$157 nightly
The price is $172 total per night from Aug 26 to Aug 27
$172 total
Aug 26 - Aug 27
Total with taxes and fees
Stay at this 3.5-star beach property in Rio Hato. Enjoy free parking, 6 outdoor pools, and a full-service spa. Popular attractions Playa Blanca and Farallón ...
Grand Decameron Panama, A Trademark All Inclusive Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama City

Packed with urban splendour and framed by the idyllic waters of the Pacific, Panama City is the modern heart of the old-world country. Avenida Central calls to visitors wanting to get lost in vibrant restaurants, galleries and market stalls, while Ancon Hill is the perfect place to take in sweeping views of the stunning city.

Panama Viejo

Dating from the 16th-century, the ruins of Panama Viejo – famously ransacked and destroyed by pirate Henry Morgan – continue to haunt the Panama of the popular imagination. Think crumbling convents, fire-ravaged towers, and the skeletons of colonial buildings being reclaimed by nature, and you have a pretty good idea of what to expect.

Nature

One of Panama’s greatest attractions is its magnificent natural beauty, and any traveler planning a trip to the capitol will want to make time to visit lush Gamboa Rainforest, just a 30-minute drive from the city. The beaches are another bucket-list draw, with the San Blas archipelago offering some of the most dazzling beaches in the world.

Terms and conditions

Special offers are only available at participating hotels. Hotel savings are based upon Expedia’s everyday hotel rates, excluding taxes and other fees. Minimum stay may be required. Offers are subject to availability and may be discontinued without notice. Additional restrictions and blackout dates may apply.

  • Please check government advisories before booking and traveling.
  • Prices are updated regularly and are accurate when published.
  • Offers are subject to limited availability and may be discontinued without notice.
  • Please click through to individual deals to confirm prices, availability and applicable terms and conditions for those deals.
  • Expedia’s usual booking terms and conditions apply.