$1,287 Cheap TAP Portugal flights Chicago (ORD) to São Tomé Island (TMS)

Finding cheap one-way TAP Portugal flights from ORD to TMS from $1,287 on Expedia is simple — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $1,459 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Scoring the best TAP Portugal deals from ORD to TMS is typically all about timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. Better yet, you can pocket 17% on average by buying your tickets on a Sunday compared to a Friday, which is often the most expensive day to book.* It's smart to kick off your flight search about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to find the earliest departures from ORD to TMS. Jetting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.