Flights to Florida Keys from St. Louis - $61

View $61 flight on Mon, Nov 17, 2025Opens in a new window

Popular airlines from St. Louis to Florida Keys

  • American Airlines

    American Airlines

  • Delta

    Delta

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from St. Louis to Florida Keys (STL-MIA)

Prices were available within the past 7 days and start at $61 for one-way flights and $138 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sun, Oct 26 - Sat, Nov 8
STL
St. Louis
MIA
Miami
$138 Roundtrip, found 6 hours ago
$138
Roundtrip
found 6 hours ago
Select Spirit Airlines flight, departing Sun, Oct 26 from St. Louis to Miami, returning Sat, Nov 8, priced at $138 found 6 hours ago
Spirit Airlines
Fri, Oct 24 - Sat, Nov 1
STL
St. Louis
MIA
Miami
$149 Roundtrip, found 2 hours ago
$149
Roundtrip
found 2 hours ago
Select Spirit Airlines flight, departing Fri, Oct 24 from St. Louis to Miami, returning Sat, Nov 1, priced at $149 found 2 hours ago
Southwest Airlines
Mon, Sep 8 - Mon, Sep 22
STL
St. Louis
MIA
Miami
$164 Roundtrip, found 3 days ago
$164
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Mon, Sep 8 from St. Louis to Miami, returning Mon, Sep 22, priced at $164 found 3 days ago
American Airlines
Mon, Sep 22 - Tue, Sep 30
STL
St. Louis
MIA
Miami
$177 Roundtrip, just found
$177
Roundtrip
just found
Select American Airlines flight, departing Mon, Sep 22 from St. Louis to Miami, returning Tue, Sep 30, priced at $177 just found
Delta
Wed, Oct 8 - Thu, Oct 16
STL
St. Louis
MIA
Miami
$178 Roundtrip, found 2 hours ago
$178
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Oct 8 from St. Louis to Miami, returning Thu, Oct 16, priced at $178 found 2 hours ago
United
Mon, Aug 18 - Tue, Aug 26
STL
St. Louis
MIA
Miami
$184 Roundtrip, found 2 hours ago
$184
Roundtrip
found 2 hours ago
Select United flight, departing Mon, Aug 18 from St. Louis to Miami, returning Tue, Aug 26, priced at $184 found 2 hours ago

Find the cheapest month to fly from St. Louis (STL) to Key West (EYW)

May is typically the cheapest month to fly

From $198 - $562 per traveler.

Graph displaying average flight prices per month

Alternative airports

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Miami Intl. MIA. Cheapest option available. Flights from $224
MIA
Miami Intl.
Cheapest
Flights from $224
Select flight to Key West Intl. EYW. Flights from $279
EYW
Key West Intl.
Flights from $279
*Available to One Key members.