- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Plan, book, fly with confidence
- Chicago to São Tomé Island
- Accra to São Tomé Island
- Miami to São Tomé Island
- Detroit to São Tomé Island
- Seattle to São Tomé Island
- New York to São Tomé Island
- Lagos to São Tomé Island
- Louisville to São Tomé Island
- Lisbon District to São Tomé Island
- Atlanta to São Tomé Island
- San Francisco to São Tomé Island
- Johannesburg to São Tomé Island
Expedia's Latest Trends
Hotels
The Mousetrap InnHoliday Inn & Suites St. Cloud, an IHG HotelHotels with an Indoor Pool in Rio RanchoExcellence HotelCabin Rentals OhioBaymont by Wyndham Pigeon Forge near Island Drive Sunnyside Inn & SuitesPort Inn & Suites Kennebunk, Ascend Hotel CollectionAdults Only Resorts & Hotels in VietnamHibernation Hideaway - Private indoor pool, theater room, hot tub, games, and more!Hotels with Free Airport Shuttle in Billings
Flights
Flights from Bucaramanga (BGA) to New York (JFK)Flights from West Columbia (CAE) to Lexington (LEX)Flights from Alexander the Great to LON-All AirportsFlights from Boston (BOS) to Lexington (LEX)Flights from Cedar Rapids (CID) to Florence (CVG)JetBlue Airways San Francisco (SFO) to Boston (BOS) flightsFlights from Tulsa to SaarbrueckenFlights from South Bend (SBN) to San Francisco (SFO)Flights from Santa FeFlights from New York (JFK) to Moline (MLI)Flights to BelgradeFlights from Indianapolis (IND) to Ho Chi Minh City (SGN)Flights from Charlotte (CLT) to Las Vegas (LAS)Flights to Denver
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