Flights to Great Britain from Des Moines - $391

View $391 flight on Sat, Oct 25, 2025Opens in a new window

Popular airlines from Des Moines to Great Britain

  • British Airways

    British Airways

  • Lufthansa

    Lufthansa

  • Virgin Atlantic

    Virgin Atlantic

  • Iberia

    Iberia

  • Air Canada

    Air Canada

  • United

    United

  • Delta

    Delta

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Cheap Flights from Des Moines to Great Britain (DSM-LON)

Prices were available within the past 7 days and start at $391 for one-way flights and $614 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Virgin Atlantic
Mon, Sep 8 - Tue, Dec 16
DSM
Des Moines
MAN
Manchester
$614 Roundtrip, found 5 days ago
$614
Roundtrip
found 5 days ago
Select Virgin Atlantic flight, departing Mon, Sep 8 from Des Moines to Manchester, returning Tue, Dec 16, priced at $614 found 5 days ago
Delta
Sun, Sep 14 - Tue, Dec 16
DSM
Des Moines
MAN
Manchester
$614 Roundtrip, found 5 days ago
$614
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Sep 14 from Des Moines to Manchester, returning Tue, Dec 16, priced at $614 found 5 days ago
Virgin Atlantic
Wed, Oct 15 - Tue, Nov 4
DSM
Des Moines
MAN
Manchester
$616 Roundtrip, found 16 hours ago
$616
Roundtrip
found 16 hours ago
Select Virgin Atlantic flight, departing Wed, Oct 15 from Des Moines to Manchester, returning Tue, Nov 4, priced at $616 found 16 hours ago
Air Canada
Wed, Oct 8 - Thu, Oct 30
DSM
Des Moines
LHR
London
$627 Roundtrip, found 6 days ago
$627
Roundtrip
found 6 days ago
Select Air Canada flight, departing Wed, Oct 8 from Des Moines to London, returning Thu, Oct 30, priced at $627 found 6 days ago
British Airways
Wed, Nov 19 - Thu, Dec 4
DSM
Des Moines
MAN
Manchester
$638 Roundtrip, found 5 days ago
$638
Roundtrip
found 5 days ago
Select British Airways flight, departing Wed, Nov 19 from Des Moines to Manchester, returning Thu, Dec 4, priced at $638 found 5 days ago
American Airlines
Wed, Nov 5 - Wed, Nov 19
DSM
Des Moines
MAN
Manchester
$639 Roundtrip, found 19 hours ago
$639
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Des Moines to Manchester, returning Wed, Nov 19, priced at $639 found 19 hours ago

Find the cheapest month to fly from Des Moines (DSM) to London (LHR)

November is typically the cheapest month to fly

From $607 - $1,488 per traveler.

Graph displaying average flight prices per month

*Available to One Key members.