$371 Cheap Flights from Cali (CLO) to Des Moines (DSM)

View $371 flight on Mon, Mar 23, 2026Opens in a new window

Popular airlines from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines International Airport (DSM)

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Cheap Flights from Cali to Des Moines (CLO-DSM)

Prices were available within the past 7 days and start at $371 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM) cost?
Secure a cheap one-way flight from $371 or cheap return flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from CLO to DSM is , when demand is low. Off-peak months are often when better flight deals are available between these airports.
What is the cheapest airline that flies from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest CLO to DSM flight.
How many flights per day from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM)?
There are no daily direct flights departing from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from CLO to DSM?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM)?
Select a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM) last-minute?
Holding off until right before your break to book a ticket from CLO to DSM generally means paying more. Although you may find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of snagging a bargain.
Is it cheaper to book a CLO to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLO to DSM flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place will take the stress out of travel planning. Just secure your flights and select from our wide range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Des Moines Intl. Airport (DSM)?
In most cases, you can modify or cancel your CLO to DSM flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you need further details, go to our Customer Service portal.

Travel information

Origin airport
Alfonso Bonilla Aragon Intl.
Destination airport
Des Moines Intl.
Distance
2834 mi

Book with confidence

Cali to Des Moines Flights

The cheapest times to fly from Cali to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cali to Des Moines are during the month of . You can find some of the cheapest flights from Cali to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cali to Des Moines

Sunday is one of the best days to book for cheap flights from Cali to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cali to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cali to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $371 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cali to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cali to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cali to Des Moines Flights

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*Available to One Key members.