$406 Cheap Flights from Des Moines (DSM) to St. John's (ANU)

View $406 flight on Sat, Oct 3, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to V.C. Bird Intl. Airport (ANU)

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Cheap Flights from Des Moines to St. John's (DSM-ANU)

Prices were available within the past 7 days and start at $406 for one-way flights and $697 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Dec 5 - Tue, Dec 15
DSM
Des Moines
ANU
Antigua
$697 Roundtrip, found 5 days ago
$697
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Dec 5 from Des Moines to Antigua, returning Tue, Dec 15, priced at $697 found 5 days ago
American Airlines
Sat, Dec 5 - Tue, Dec 15
DSM
Des Moines
ANU
Antigua
$704 Roundtrip, found 5 days ago
$704
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Dec 5 from Des Moines to Antigua, returning Tue, Dec 15, priced at $704 found 5 days ago
American Airlines
Tue, Oct 20 - Tue, Oct 27
DSM
Des Moines
ANU
Antigua
$707 Roundtrip, found 7 hours ago
$707
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Oct 20 from Des Moines to Antigua, returning Tue, Oct 27, priced at $707 found 7 hours ago
American Airlines
Sat, Dec 5 - Tue, Dec 15
DSM
Des Moines
ANU
Antigua
$708 Roundtrip, found 5 days ago
$708
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Dec 5 from Des Moines to Antigua, returning Tue, Dec 15, priced at $708 found 5 days ago
American Airlines
Sat, Apr 18 - Thu, Apr 23
DSM
Des Moines
ANU
Antigua
$711 Roundtrip, found 5 days ago
$711
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Apr 18 from Des Moines to Antigua, returning Thu, Apr 23, priced at $711 found 5 days ago
American Airlines
Tue, Oct 20 - Tue, Oct 27
DSM
Des Moines
ANU
Antigua
$714 Roundtrip, found 7 hours ago
$714
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Oct 20 from Des Moines to Antigua, returning Tue, Oct 27, priced at $714 found 7 hours ago
American Airlines
Tue, Oct 20 - Tue, Oct 27
DSM
Des Moines
ANU
Antigua
$716 Roundtrip, found 7 hours ago
$716
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Oct 20 from Des Moines to Antigua, returning Tue, Oct 27, priced at $716 found 7 hours ago
Delta
Sat, Aug 1 - Sat, Aug 15
DSM
Des Moines
ANU
Antigua
$778 Roundtrip, found 4 days ago
$778
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Aug 1 from Des Moines to Antigua, returning Sat, Aug 15, priced at $778 found 4 days ago
Air Canada
Fri, Nov 27 - Sat, Nov 28
DSM
Des Moines
ANU
Antigua
$1,330 Roundtrip, found 7 hours ago
$1,330
Roundtrip
found 7 hours ago
Select Air Canada flight, departing Fri, Nov 27 from Des Moines to Antigua, returning Sat, Nov 28, priced at $1,330 found 7 hours ago
United
Fri, Nov 27 - Sat, Nov 28
DSM
Des Moines
ANU
Antigua
$2,080 Roundtrip, found 7 hours ago
$2,080
Roundtrip
found 7 hours ago
Select United flight, departing Fri, Nov 27 from Des Moines to Antigua, returning Sat, Nov 28, priced at $2,080 found 7 hours ago

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Alternative airports near Osbourn

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to V.C. Bird Intl. ANU. Cheapest option available. Flights from $820
ANU
V.C. Bird Intl.
Cheapest
Flights from $820

Find the cheapest month to fly from Des Moines (DSM) to Osbourn (ANU)

March is typically the cheapest month to fly

From $633 - $976 per traveler.
Flights from Des Moines (DSM) to St. John's (ANU)
Origin airport
Des Moines Intl.
Destination airport
V.C. Bird Intl.
Airlines serving
Air Canada, American Airlines, Delta
Roundtrip price
$696
Distance
2527 mi

Des Moines to St. John's Flights

The cheapest times to fly from Des Moines to St. John's

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to St. John's are during the month of December. You can find some of the cheapest flights from Des Moines to St. John's with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to St. John's

Sunday is one of the best days to book for cheap flights from Des Moines to St. John's: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to St. John's

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to St. John's in 2026. You can also book with separate airlines for your outbound and return journeys, from $406 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to St. John's flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to St. John's airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU) cost?
Get a cheap one-way flight from $406 or cheap return flight from $697 from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU)?
December is the least expensive month to fly from DSM to ANU. Traveling outside of peak seasons is often the key to finding a great deal.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest DSM to ANU flight.
How many flights per day from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU)?
There aren't any daily nonstop flights from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from DSM to ANU?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU)?
To land at V.C. Bird Intl. Airport (ANU) on schedule, opt for a flight that leaves Des Moines Intl. Airport (DSM) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU) last-minute?
Booking your flight from DSM to ANU right before your journey is generally more expensive. However, if you're flexible with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a DSM to ANU flight and hotel package?
Opting for a DSM to ANU flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our impressive range of stays and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to V.C. Bird Intl. Airport (ANU)?
Usually, it's possible to cancel or reschedule your DSM to ANU flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

*Flight schedules are subject to change.

*Available to One Key members.