Title: Cheap flights to Cali from Des Moines (DSM to CLO) - Expedia.com ![](https://images.trvl-media.com/place/863/af7bd056-55f4-44ec-bf23-ecdc05ded06f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/863/af7bd056-55f4-44ec-bf23-ecdc05ded06f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $357 Cheap Flights from Des Moines (DSM) to Cali (CLO) [View $357 flight on Mon, Jun 1, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:356.40&airProductToken=AQqYAQoxCNWCARIENjA1MBjDZCCuHCiry44DMJLMjgM4S0AAWAFqBUxJR0hUcghTTE1CMU5SOQowCMGsARIDMjYzGK4cIMEzKOTMjgMw1s-OAzhTQAFYAWoFTElHSFRyCFNMTUIxTlI5CjEIwawBEgQ4NDExGMEzIOJyKOvSjgMwp9OOAzhTQAFYAWoFTElHSFRyCFNMTUIxTlI5EgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) ## Popular airlines from Des Moines International Airport (DSM) to Alfonso Bonilla Aragon Intl. Airport (CLO) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:CLO,departure:4/3/2026TANYT&leg2=from:CLO,to:DSM,departure:4/10/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:CLO,departure:4/3/2026TANYT&leg2=from:CLO,to:DSM,departure:4/10/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:CLO,departure:4/3/2026TANYT&leg2=from:CLO,to:DSM,departure:4/10/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:CLO,departure:4/3/2026TANYT&leg2=from:CLO,to:DSM,departure:4/10/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:CLO,departure:4/3/2026TANYT&leg2=from:CLO,to:DSM,departure:4/10/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Des Moines to Cali (DSM-CLO) Prices were available within the past 7 days and start at $357 for one-way flights and $666 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $666 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:665.23&airProductToken=AQplCjEIwYIBEgQzNjY5GMNkIIwCKMrEjgMwkMaOAzhCQABYAWoFQkFTSUNyCFNMWDVJSEJaCjAIwYIBEgM5MjEYjAIg4nIo9smOAzDYy44DOEJAAVgBagVCQVNJQ3IIU0xYNUlIQloKmAEKMQjBggESBDExNDIY4nIgjAIoq5ORAzCXlZEDOEJAAFgBagVCQVNJQ3IIT0xVNUlCQloKMAjBggESAzU4MRiMAiCuHCiAlpEDMNKXkQM4QkABWAFqBUJBU0lDcghPTFU1SUJCWgoxCMGCARIENDY3NhiuHCDDZCjomJEDMMqZkQM4QkABWAFqBUJBU0lDcghPTFU1SUJCWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $695 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:694.23&airProductToken=AQqYAQoxCMGCARIENDQ2MxjDZCDvWSjWxI4DMPjFjgM4QkAAWAFqBUJBU0lDcghTTFg1SUhCWgoxCMGCARIEMzI2NRjvWSCMAiiSyI4DMMXJjgM4QkABWAFqBUJBU0lDcghTTFg1SUhCWgowCMGCARIDOTIxGIwCIOJyKPbJjgMw2MuOAzhCQAFYAWoFQkFTSUNyCFNMWDVJSEJaCpsBCjEIwYIBEgQxMTQyGOJyIIwCKKuTkQMwl5WRAzhCQABYAWoFQkFTSUNyCFFMVTVJQkJaCjIIwYIBEgQzMDgxGIwCIKOxASjNl5EDMJKZkQM4QkABWAFqBUJBU0lDcghRTFU1SUJCWgoyCMGCARIEMjQyMRijsQEgw2Qo_JmRAzDvmpEDOEJAAVgBagVCQVNJQ3IIUUxVNUlCQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $723 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:722.23&airProductToken=AQqaAQoyCMGCARIEMjg1NBjDZCDimgEoi8WOAzCgxo4DOEJAAFgBagVCQVNJQ3IIUUxVNUlCQloKMgjBggESBDI5MTIY4poBIIwCKNrHjgMw2siOAzhCQAFYAWoFQkFTSUNyCFFMVTVJQkJaCjAIwYIBEgM5MjEYjAIg4nIo9smOAzDYy44DOEJAAVgBagVCQVNJQ3IIUUxVNUlCQloKmQEKMQjBggESBDExNDIY4nIgjAIoq5ORAzCXlZEDOEJAAFgBagVCQVNJQ3IIUUxVNUlCQloKMQjBggESBDIxMjkYjAIg71kohZaRAzC1l5EDOEJAAVgBagVCQVNJQ3IIUUxVNUlCQloKMQjBggESBDUxNjUY71kgw2Qog5iRAzC7mZEDOEJAAVgBagVCQVNJQ3IIUUxVNUlCQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $753 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:752.23&airProductToken=AQqWAQowCMGCARIENTY0NRjDZCBDKPLEjgMwj8aOAzhCQABYAWoFQkFTSUNyCFNMWDVJSEJaCjAIwYIBEgQyOTE1GEMgjAIo6MeOAzCRyY4DOEJAAVgBagVCQVNJQ3IIU0xYNUlIQloKMAjBggESAzkyMRiMAiDicij2yY4DMNjLjgM4QkABWAFqBUJBU0lDcghTTFg1SUhCWgqbAQoxCMGCARIEMTE0MhjiciCMAiirk5EDMJeVkQM4QkAAWAFqBUJBU0lDcghOTFU4R0JCWgoyCMGCARIEMTIyNxiMAiCjsQEo-JaRAzDAmJEDOEJAAVgBagVCQVNJQ3IITkxVOEdCQloKMgjBggESBDI0MjEYo7EBIMNkKPyZkQMw75qRAzhCQAFYAWoFQkFTSUNyCE5MVThHQkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $765 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:764.23&airProductToken=AQqWAQowCMGCARIENTY0NRjDZCBDKPLEjgMwj8aOAzhCQABYAWoFQkFTSUNyCFNMWDVJSEJaCjAIwYIBEgQyOTE1GEMgjAIo6MeOAzCRyY4DOEJAAVgBagVCQVNJQ3IIU0xYNUlIQloKMAjBggESAzkyMRiMAiDicij2yY4DMNjLjgM4QkABWAFqBUJBU0lDcghTTFg1SUhCWgqZAQoxCMGCARIEMTE0MhjiciCMAiirk5EDMJeVkQM4QkAAWAFqBUJBU0lDcghWTE4wQUhCWgoxCMGCARIEMTQzMRiMAiCuHCjflpEDMLOYkQM4QkABWAFqBUJBU0lDcghWTE4wQUhCWgoxCMGCARIENDY3NhiuHCDDZCjomJEDMMqZkQM4QkABWAFqBUJBU0lDcghWTE4wQUhCWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $781 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:780.23&airProductToken=AQqYAQoxCMGCARIENDQ2MxjDZCDvWSjWxI4DMPjFjgM4QkAAWAFqBUJBU0lDcghOTFU4R0JCWgoxCMGCARIEMzMwMhjvWSCMAijlxo4DMJbIjgM4QkABWAFqBUJBU0lDcghOTFU4R0JCWgowCMGCARIDOTIxGIwCIOJyKPbJjgMw2MuOAzhCQAFYAWoFQkFTSUNyCE5MVThHQkJaCpsBCjEIwYIBEgQxMTQyGOJyIIwCKKuTkQMwl5WRAzhCQABYAWoFQkFTSUNyCFFMVTVJQkJaCjIIwYIBEgQzMDgxGIwCIKOxASjNl5EDMJKZkQM4QkABWAFqBUJBU0lDcghRTFU1SUJCWgoyCMGCARIEMjQyMRijsQEgw2Qo_JmRAzDvmpEDOEJAAVgBagVCQVNJQ3IIUUxVNUlCQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Mon, Dec 7 - Mon, Dec 14 DSM Des Moines CLO Cali $838 Roundtrip found 2 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:12/7/2026TANYT&leg2=from:CLO,to:DSM,departure:12/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:837.13&airProductToken=AQqnAQo6CMyCARIENjgzMRjDZCDgXCjglZ8DMOGWnwM4WEAAWAFqAlNMcghYTFhTTEQ5WHoKCMSYARIEMTcwNAo5CMyCARIENjM1MRjgXCDBMyiLl58DMJ6ZnwM4WEABWAFqAlNMcghYTFhTTEQ5WHoJCMSYARIDOTgxCi4IzIIBEgQ0MDcxGMEzIOJyKOaanwMwp5ufAzhYQAFYAWoCU0xyCFhMWFNMRDlYCqgBCi4IzIIBEgQ0Mzc4GOJyIOI0KMPpnwMwmeqfAzhOQABYAWoCU0xyCE5MWFNMNUdYCjoIzIIBEgQ2MzYyGOI0IOBcKKnxnwMwrfOfAzhOQAFYAWoCU0xyCE5MWFNMNUdYegoIxJgBEgQ2MzYyCjoIzIIBEgQ2ODM0GOBcIMNkKIf0nwMwjfWfAzhOQAFYAWoCU0xyCE5MWFNMNUdYegoIxJgBEgQyMzA2EgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $848 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:847.53&airProductToken=AQqYAQoxCNWCARIENjA1MBjDZCCuHCiry44DMJLMjgM4S0AAWAFqBUxJR0hUcghTTE1CMU5SOQowCMGsARIDMjYzGK4cIMEzKOTMjgMw1s-OAzhTQAFYAWoFTElHSFRyCFNMTUIxTlI5CjEIwawBEgQ4NDExGMEzIOJyKOvSjgMwp9OOAzhTQAFYAWoFTElHSFRyCFNMTUIxTlI5EgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Jun 1 - Tue, Jun 30 DSM Des Moines CLO Cali $1,528 Roundtrip found 5 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:6/1/2026TANYT&leg2=from:CLO,to:DSM,departure:6/30/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1527.23&airProductToken=AQqwAQo1CMSYARIEMjcyNxjDZCDgXCizxI4DMLfFjgM4S0AAWAFqCU1BSU5DTEFTQ3IIS0xYRjBOTVAKNAjEmAESAzk4MhjgXCDBMyj_xY4DMKDIjgM4S0ABWAFqCU1BSU5DTEFTQ3IIS0xYRjBOTVAKQQjEmAESBDc0MDMYwTMg4nIopsuOAzDny44DOEtAAVgBaglNQUlOQ0xBU0NyCEtMWEYwTk1QegoIzIIBEgQ0MDgzEgoIARABGAEqAkRMGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Mon, Dec 7 - Mon, Dec 14 DSM Des Moines CLO Cali $4,708 Roundtrip found 2 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:CLO,departure:12/7/2026TANYT&leg2=from:CLO,to:DSM,departure:12/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:4707.39&airProductToken=AQqpAQo-CMGsARIEMjMwORjDZCCuHCjbl58DMK6YnwM4SEAAWAFqB0NMQVNTSUNyCEhMUkIyQlJTegkI1YIBEgMzMTIKMgjBrAESAzI2MxiuHCDBMyiEm58DMPadnwM4SEABWAFqB0NMQVNTSUNyCEhMUkIyQlJTCjMIwawBEgQ4NTIzGMEzIOJyKM2fnwMwjqCfAzhIQAFYAWoHQ0xBU1NJQ3IISExSQjJCUlMKqgEKMwjBrAESBDg0MjIY4nIgwTMo5OSfAzCg5Z8DOEJAAFgBagdDTEFTU0lDcghCTFJCMkJSUwoyCMGsARIDMjYyGMEzIK4cKOblnwMw7OifAzhCQAFYAWoHQ0xBU1NJQ3IIQkxSQjJCUlMKPwjBrAESBDIzMTQYrhwgw2Qo6fOfAzDF9J8DOEJAAVgBagdDTEFTU0lDcghCTFJCMkJSU3oKCNWCARIEMTgzORIKCAEQARgBKgJBVhgBIgQIARABKAIoAygEMAE) ## Frequently asked questions ### How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) cost? ### What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ### How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight with Expedia? ### What airports do you fly into for Cali from Des Moines Intl. (DSM)? ### Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) at the last minute? ### Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight and hotel package? ### Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)? ## Travel information | Origin airport | Des Moines Intl. | | ------------------- | ------------------------------------------------------ | | Destination airport | Alfonso Bonilla Aragon Intl. | | Airlines serving | American Airlines, Delta, LATAM Airlines Group, United | | Roundtrip price | $665 | | Distance | 2834 mi | ## Book with confidence # Des Moines to Cali Flights The cheapest times to fly from Des Moines to Cali On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Cali are during the month of June. You can find some of the cheapest flights from Des Moines to Cali with Expedia's search tool and vast selection of airlines. The best time to book a flight from Des Moines to Cali Sunday is one of the best days to book for cheap flights from Des Moines to Cali: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. How to find cheap round-trip tickets from Des Moines to Cali Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Cali in 2026\. You can also book with separate airlines for your outbound and return journeys, from $357 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Cali flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Des Moines to Cali airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. \*Terms apply. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. \*Flight schedules are subject to change. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Centro Comercial Llanogrande Plaza ](https://www.expedia.com/Centro-Comercial-Llanogrande-Plaza-Hotels.0-l553248633937786843-0.Travel-Guide-Filter-Hotels) - [Hotels near Rozo ](https://www.expedia.com/Rozo-Cali-Hotels.0-n6324258-0.Travel-Guide-Filter-Hotels) - [Hotels near Parque Bolivar ](https://www.expedia.com/Parque-Bolivar-Hotels.0-l553248633938878833-0.Travel-Guide-Filter-Hotels) - [Yumbo Hotels ](https://www.expedia.com/Yumbo-Hotels.d6160080.Travel-Guide-Hotels) - [Hostels in Yumbo ](https://www.expedia.com/Yumbo-Hostels.d6160080-aaHostels.Travel-Guide-Accommodation) - [Motels in Yumbo ](https://www.expedia.com/Yumbo-Motels.d6160080-aaMotels.Travel-Guide-Accommodation) - [Romantic Hotels in Yumbo ](https://www.expedia.com/Yumbo-Hotels-Romantic-Hotel.0-0-d6160080-tRomanticHotel.Travel-Guide-Filter-Hotels) - 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[Palmira Vacation Rentals ](https://www.expedia.com/Palmira-Vacation-Rentals.d6324233.Travel-Guide-VacationRentals) - [Things to do in Yumbo ](https://www.expedia.com/Things-To-Do-In-Yumbo.d6160080.Travel-Guide-Activities) - [Things to do in El Cerrito ](https://www.expedia.com/Things-To-Do-In-El-Cerrito.d6203851.Travel-Guide-Activities) - [Things to do in Palmira ](https://www.expedia.com/Things-To-Do-In-Palmira.d6324233.Travel-Guide-Activities) \*Available to One Key members.