Title: Cheap flights from Des Moines to Jackson (DSM to MKL) - Expedia.com ![The legendary train operated by the famous Casey Jones. ](https://images.trvl-media.com/place/6059452/fce203de-7fe4-4619-af25-a189d8ac32a8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Roquita Williams ![](https://images.trvl-media.com/place/6059452/fce203de-7fe4-4619-af25-a189d8ac32a8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Des Moines (DSM) to Jackson (MKL) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travelers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Des Moines International Airport (DSM) to Jackson, TN (MKL-McKellar-Sipes Regional) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Des Moines to Jackson (DSM-MKL) Prices were available within the past 7 days and start at for one-way flights and $418 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Sat, Apr 18 - Mon, Apr 20 DSM Des Moines MKL Jackson $418 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/18/2026TANYT&leg2=from:MKL,to:DSM,departure:4/20/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:417.59&airProductToken=AQpECiAI1YIBEgQyNjY4GMNkIK4cKNDWigMwrNeKAzhLQABYAQogCMuOARIENTg4MhiuHCDMWiiO2ooDMPzaigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCje7ooDMMLvigM4VEAAWAEKIAjVggESBDIyNjUYrhwgw2Qo1_KKAzCz84oDOEtAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Feb 17 - Fri, Feb 20 DSM Des Moines MKL Jackson $424 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/17/2026TANYT&leg2=from:MKL,to:DSM,departure:2/20/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:423.80&airProductToken=AQpECiAI1YIBEgQ1MjE5GMNkIK4cKJe5hQMw97mFAzhMQABYAQogCMuOARIENTg4MhiuHCDMWijqwoUDMNjDhQM4UUABWAEKQwogCMuOARIENTg4MBjMWiCuHCi614UDMJ7YhQM4UUAAWAEKHwjVggESAzIxMxiuHCDDZCjC24UDMJ3chQM4TEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Fri, Apr 17 - Sat, Apr 18 DSM Des Moines MKL Jackson $438 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/17/2026TANYT&leg2=from:MKL,to:DSM,departure:4/18/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:437.59&airProductToken=AQpECiAI1YIBEgQyNjY4GMNkIK4cKLDLigMwjMyKAzhMQABYAQogCMuOARIENTg4MhiuHCDMWijuzooDMNzPigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCie2IoDMILZigM4VEAAWAEKIAjVggESBDIyNjUYrhwgw2Qol9yKAzDz3IoDOEtAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Sun, Apr 19 - Mon, Apr 20 DSM Des Moines MKL Jackson $441 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/19/2026TANYT&leg2=from:MKL,to:DSM,departure:4/20/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:440.59&airProductToken=AQpECiAI1YIBEgQyNjY4GMNkIK4cKPDhigMwzOKKAzhMQABYAQogCMuOARIENTg4MhiuHCDMWiiu5YoDMJzmigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCje7ooDMMLvigM4VEAAWAEKIAjVggESBDIyNjUYrhwgw2Qo1_KKAzCz84oDOEtAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Feb 19 - Sat, Feb 21 DSM Des Moines MKL Jackson $444 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/19/2026TANYT&leg2=from:MKL,to:DSM,departure:2/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:443.40&airProductToken=AQpoCiEIxJgBEgQ1NDE0GMNkIOO0ASjjyYUDMNPKhQM4WEAAWAEKIQjEmAESBDQ0ODEY47QBIK4cKLLMhQMwiM2FAzhYQAFYAQogCMuOARIENTg4MhiuHCDMWiiKzoUDMPjOhQM4UUABWAEKZwogCMuOARIENTg4MBjMWiCuHCja4oUDML7jhQM4UUAAWAEKIQjEmAESBDM2ODEY7LABIMx8KKTlhQMwlOaFAzhYQAFYAQogCMSYARIENTI1MxjMfCDDZCjR5oUDMKjnhQM4WEABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Feb 17 - Sun, Mar 1 DSM Des Moines MKL Jackson $444 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/17/2026TANYT&leg2=from:MKL,to:DSM,departure:3/1/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:443.70&airProductToken=AQpECiAI1YIBEgQ1MjE5GMNkIK4cKJe5hQMw97mFAzhMQABYAQogCMuOARIENTg4MhiuHCDMWijqwoUDMNjDhQM4UUABWAEKRAogCMuOARIENTg4MBjMWiCuHCjavIYDML69hgM4VEAAWAEKIAjVggESBDE4MzAYrhwgw2Qo1MiGAzCryYYDOExAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Thu, Feb 19 - Mon, Feb 23 DSM Des Moines MKL Jackson $454 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/19/2026TANYT&leg2=from:MKL,to:DSM,departure:2/23/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:453.80&airProductToken=AQpDCh8I1YIBEgMzMTIYw2QgrhwohM6FAzDkzoUDOFRAAFgBCiAIy44BEgQ1ODgyGK4cIMxaKKrZhQMwmNqFAzhRQAFYAQpECiAIy44BEgQ1ODgwGMxaIK4cKJr5hQMw_vmFAzhRQABYAQogCNWCARIEMTgzMBiuHCDDZCiUhYYDMOuFhgM4TEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, Feb 13 - Sat, Feb 14 DSM Des Moines MKL Jackson $459 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/13/2026TANYT&leg2=from:MKL,to:DSM,departure:2/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:458.80&airProductToken=AQpaCjAIwYIBEgQ0ODk5GMNkIK4cKISIhQMw4YiFAzhPQABYAWoETUFJTnIITzdBWlpOTTEKJgjLjgESBDU4ODIYrhwgzFooyoqFAzC4i4UDOFFAAVgBcgRRN05TCloKJgjLjgESBDU4ODAYzFogrhwo-pOFAzDelIUDOFFAAFgBcgRRN05TCjAIwYIBEgQzNjUzGK4cIMNkKL6WhQMwk5eFAzhPQAFYAWoETUFJTnIITzdBSUpTTTMSDAgBEAEYASoCQUEyABgBIgQIARABKAIoAygEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Fri, Apr 17 - Sun, Apr 19 DSM Des Moines MKL Jackson $461 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/17/2026TANYT&leg2=from:MKL,to:DSM,departure:4/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:460.60&airProductToken=AQpECiAI1YIBEgQyNjY4GMNkIK4cKLDLigMwjMyKAzhMQABYAQogCMuOARIENTg4MhiuHCDMWijuzooDMNzPigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCi-44oDMKLkigM4VEAAWAEKIAjVggESBDU5MTYYrhwgw2QojuiKAzDv6IoDOExAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, Feb 13 - Sat, Feb 14 DSM Des Moines MKL Jackson $469 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/13/2026TANYT&leg2=from:MKL,to:DSM,departure:2/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:468.60&airProductToken=AQqOAQoxCMGCARIEMjQ4OBjDZCDimgEozIaFAzDfh4UDOE9AAFgBagRNQUlOcghPN0FaWk5NMQoxCMGCARIEMjMxORjimgEgrhwo-IiFAzCAioUDOE9AAVgBagRNQUlOcghPN0FaWk5NMQomCMuOARIENTg4MhiuHCDMWijKioUDMLiLhQM4UUABWAFyBFE3TlMKWgomCMuOARIENTg4MBjMWiCuHCj6k4UDMN6UhQM4UUAAWAFyBFE3TlMKMAjBggESBDM2NTMYrhwgw2QovpaFAzCTl4UDOE9AAVgBagRNQUlOcghPN0FJSlNNMxIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwAQ) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Feb 12 - Sat, Feb 21 DSM Des Moines MKL Jackson $474 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/12/2026TANYT&leg2=from:MKL,to:DSM,departure:2/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:473.40&airProductToken=AQpoCiEIxJgBEgQ1NDE0GMNkIOO0ASiD-4QDMPP7hAM4VEAAWAEKIQjEmAESBDQ0ODEY47QBIK4cKNL9hAMwqP6EAzhUQAFYAQogCMuOARIENTg4MhiuHCDMWiiq_4QDMJiAhQM4UUABWAEKZwogCMuOARIENTg4MBjMWiCuHCja4oUDML7jhQM4UUAAWAEKIQjEmAESBDM2ODEY7LABIMx8KKTlhQMwlOaFAzhYQAFYAQogCMSYARIENTI1MxjMfCDDZCjR5oUDMKjnhQM4WEABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Thu, Feb 19 - Sun, Mar 1 DSM Des Moines MKL Jackson $474 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/19/2026TANYT&leg2=from:MKL,to:DSM,departure:3/1/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:473.70&airProductToken=AQpDCh8I1YIBEgMzMTIYw2QgrhwohM6FAzDkzoUDOFRAAFgBCiAIy44BEgQ1ODgyGK4cIMxaKKrZhQMwmNqFAzhRQAFYAQpECiAIy44BEgQ1ODgwGMxaIK4cKNq8hgMwvr2GAzhUQABYAQogCNWCARIEMTgzMBiuHCDDZCjUyIYDMKvJhgM4TEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Feb 17 - Thu, Feb 19 DSM Des Moines MKL Jackson $484 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/17/2026TANYT&leg2=from:MKL,to:DSM,departure:2/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:483.79&airProductToken=AQpECiAI1YIBEgQ1MjE5GMNkIK4cKJe5hQMw97mFAzhMQABYAQogCMuOARIENTg4MhiuHCDMWijqwoUDMNjDhQM4UUABWAEKQwogCMuOARIENTg4MBjMWiCuHCiazIUDMP7MhQM4UUAAWAEKHwjVggESAzIxMxiuHCDDZCii0IUDMP3QhQM4U0ABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, Apr 13 - Sat, Apr 18 DSM Des Moines MKL Jackson $487 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/13/2026TANYT&leg2=from:MKL,to:DSM,departure:4/18/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:486.59&airProductToken=AQpECiAI1YIBEgQ1MzQwGMNkIK4cKMidigMwqJ6KAzhTQABYAQogCMuOARIENTg4MhiuHCDMWijuoYoDMNyiigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCie2IoDMILZigM4VEAAWAEKIAjVggESBDIyNjUYrhwgw2Qol9yKAzDz3IoDOEtAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Feb 12 - Sat, Feb 14 DSM Des Moines MKL Jackson $504 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/12/2026TANYT&leg2=from:MKL,to:DSM,departure:2/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:503.41&airProductToken=AQpoCiEIxJgBEgQ1NDE0GMNkIOO0ASiD-4QDMPP7hAM4VEAAWAEKIQjEmAESBDQ0ODEY47QBIK4cKNL9hAMwqP6EAzhUQAFYAQogCMuOARIENTg4MhiuHCDMWiiq_4QDMJiAhQM4UUABWAEKZwogCMuOARIENTg4MBjMWiCuHCj6k4UDMN6UhQM4UUAAWAEKIQjEmAESBDM2ODEY7LABIMx8KMSWhQMwtJeFAzhUQAFYAQogCMSYARIENTI1MxjMfCDDZCjxl4UDMMiYhQM4VEABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, Apr 13 - Sun, Apr 19 DSM Des Moines MKL Jackson $510 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:4/13/2026TANYT&leg2=from:MKL,to:DSM,departure:4/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:509.59&airProductToken=AQpECiAI1YIBEgQ1MzQwGMNkIK4cKMidigMwqJ6KAzhTQABYAQogCMuOARIENTg4MhiuHCDMWijuoYoDMNyiigM4VEABWAEKRAogCMuOARIENTg4MBjMWiCuHCi-44oDMKLkigM4VEAAWAEKIAjVggESBDU5MTYYrhwgw2QojuiKAzDv6IoDOExAAVgBEgoIARABGAEqAlVBGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, Feb 11 - Thu, Feb 19 DSM Des Moines MKL Jackson $514 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/11/2026TANYT&leg2=from:MKL,to:DSM,departure:2/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:513.80&airProductToken=AQpECiAI1YIBEgQxMzYzGMNkIK4cKMjwhAMwqvGEAzhUQABYAQogCMuOARIENTg4MhiuHCDMWiiK9IQDMPj0hAM4UUABWAEKQwogCMuOARIENTg4MBjMWiCuHCiazIUDMP7MhQM4UUAAWAEKHwjVggESAzIxMxiuHCDDZCii0IUDMP3QhQM4U0ABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Feb 12 - Mon, Feb 23 DSM Des Moines MKL Jackson $534 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/12/2026TANYT&leg2=from:MKL,to:DSM,departure:2/23/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:533.40&airProductToken=AQpoCiEIxJgBEgQ1NDE0GMNkIOO0ASiD-4QDMPP7hAM4VEAAWAEKIQjEmAESBDQ0ODEY47QBIK4cKNL9hAMwqP6EAzhUQAFYAQogCMuOARIENTg4MhiuHCDMWiiq_4QDMJiAhQM4UUABWAEKZgogCMuOARIENTg4MBjMWiCuHCia-YUDMP75hQM4UUAAWAEKIAjEmAESBDM5NDEYrhwgzHwop_uFAzCM_IUDOFVAAVgBCiAIxJgBEgQ1MjUzGMx8IMNkKJH9hQMw6P2FAzhVQAFYARIKCAEQARgBKgJETBgBIgQIARABKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Sun, Feb 8 - Tue, Feb 10 DSM Des Moines MKL Jackson $539 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/8/2026TANYT&leg2=from:MKL,to:DSM,departure:2/10/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:538.80&airProductToken=AQpECiAI1YIBEgQ1MjE5GMNkIK4cKPDThAMwzdSEAzhXQABYAQogCMuOARIENTg4MhiuHCDMWijK3YQDMLjehAM4UUABWAEKQwogCMuOARIENTg4MBjMWiCuHCj65oQDMN7nhAM4UUAAWAEKHwjVggESAzIxMxiuHCDDZCiM64QDMObrhAM4VEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, Feb 20 - Sat, Feb 21 DSM Des Moines MKL Jackson $541 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/21/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:540.79&airProductToken=AQpaCjAIwYIBEgQzOTA2GMNkIK4cKJDVhQMw7dWFAzhRQABYAWoETUFJTnIIUTdBWlpOTTEKJgjLjgESBDU4ODIYrhwgzFooqtmFAzCY2oUDOFFAAVgBcgRRN05TCloKJgjLjgESBDU4ODAYzFogrhwo2uKFAzC-44UDOFFAAFgBcgRRN05TCjAIwYIBEgQzNjUzGK4cIMNkKJ7lhQMw8-WFAzhRQAFYAWoETUFJTnIIUTBBSUpTTTESCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAB) ## Alternative airports near Jackson Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/24/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) MKL McKellar-Sipes Regional CheapestClosest 11 min [Flights from $424 ](https://www.expedia.com/Flights-Search?leg1=from:DSM,to:MKL,departure:2/20/2026TANYT&leg2=from:MKL,to:DSM,departure:2/24/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) __Flights from Des Moines (DSM) to Jackson (MKL)__ | Origin airport | Des Moines Intl. | | ------------------- | ----------------------- | | Destination airport | McKellar-Sipes Regional | | Roundtrip price | $418 | | Distance | 482 mi | ## Des Moines to Jackson Flights The cheapest times to fly from Des Moines to Jackson On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Jackson are during the month of April. You can find some of the cheapest flights from Des Moines to Jackson with Expedia's search tool and vast selection of airlines. The best time to book a flight from Des Moines to Jackson Sunday is one of the best days to book for cheap flights from Des Moines to Jackson: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. How to find cheap round-trip tickets from Des Moines to Jackson Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Jackson in 2026\. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Jackson flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Des Moines to Jackson airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. \*Terms apply. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. ## Frequently asked questions ### How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional) cost? ### What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? ### How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional) flight with Expedia? ### What airports do you fly into for Jackson from Des Moines Intl. (DSM)? ### Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional) at the last minute? ### Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional) flight and hotel package? ### Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Jackson, TN (MKL-McKellar-Sipes Regional)? \*Flight schedules are subject to change. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Cypress Grove Nature Park ](https://www.expedia.com/Cypress-Grove-Nature-Park-Hotels.0-l553248621532655192-0.Travel-Guide-Filter-Hotels) - [Jackson Hotels ](https://www.expedia.com/Jackson-Hotels.d6059452.Travel-Guide-Hotels) - [Hotels near Century Farm Winery ](https://www.expedia.com/Century-Farm-Winery-Hotels.0-l553248621532655189-0.Travel-Guide-Filter-Hotels) - [Hotels near Rusty's TV and Movie Car Museum ](https://www.expedia.com/Rustys-TV-And-Movie-Car-Museum-Hotels.0-l553248621532655191-0.Travel-Guide-Filter-Hotels) - 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