$710 Cheap Flights from Florence (FLO) to Columbia (CAE)

View $710 flight on Sat, Apr 25, 2026Opens in a new window

Popular airlines from Florence, SC (FLO-Florence Regional) to Columbia Metropolitan Airport (CAE)

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Cheap Flights from Florence to Columbia (FLO-CAE)

Prices were available within the past 7 days and start at $710 for one-way flights and $497 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, May 22 - Sat, May 23
FLO
Florence
CAE
Columbia
$497 Roundtrip, found 4 days ago
$497
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 22 from Florence to Columbia, returning Sat, May 23, priced at $497 found 4 days ago
American Airlines
Sat, Apr 25 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$607 Roundtrip, found 5 days ago
$607
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Apr 25 from Florence to Columbia, returning Sun, Apr 26, priced at $607 found 5 days ago
American Airlines
Thu, Jun 25 - Sun, Jun 28
FLO
Florence
CAE
Columbia
$685 Roundtrip, found 4 days ago
$685
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jun 25 from Florence to Columbia, returning Sun, Jun 28, priced at $685 found 4 days ago
American Airlines
Fri, May 22 - Sat, May 23
FLO
Florence
CAE
Columbia
$809 Roundtrip, found 4 days ago
$809
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 22 from Florence to Columbia, returning Sat, May 23, priced at $809 found 4 days ago
American Airlines
Fri, May 22 - Sat, May 23
FLO
Florence
CAE
Columbia
$873 Roundtrip, found 4 days ago
$873
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 22 from Florence to Columbia, returning Sat, May 23, priced at $873 found 4 days ago
American Airlines
Fri, May 22 - Sat, May 23
FLO
Florence
CAE
Columbia
$890 Roundtrip, found 4 days ago
$890
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, May 22 from Florence to Columbia, returning Sat, May 23, priced at $890 found 4 days ago
American Airlines
Thu, Jun 25 - Sun, Jun 28
FLO
Florence
CAE
Columbia
$899 Roundtrip, found 4 days ago
$899
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jun 25 from Florence to Columbia, returning Sun, Jun 28, priced at $899 found 4 days ago
American Airlines
Sat, Apr 25 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$909 Roundtrip, found 5 days ago
$909
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Apr 25 from Florence to Columbia, returning Sun, Apr 26, priced at $909 found 5 days ago
American Airlines
Sat, Apr 25 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$911 Roundtrip, found 5 days ago
$911
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Apr 25 from Florence to Columbia, returning Sun, Apr 26, priced at $911 found 5 days ago
American Airlines
Sat, Apr 25 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$984 Roundtrip, found 5 days ago
$984
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Apr 25 from Florence to Columbia, returning Sun, Apr 26, priced at $984 found 5 days ago

Frequently asked questions

How much does a flight from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) cost?
You can find cheap one-way flights from $710 and cheap return flights from $497 FLO to CAE with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when FLO to CAE ticket fares go up or down.
What is the cheapest month to fly from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
The cheapest month to fly from FLO to CAE is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
Enter FLO to CAE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
American Airlines is the only carrier that flies from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan). Use Expedia's flight search tool to compare airlines on this route and find our cheapest option for your trip. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
To find a cheap flight from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from FLO to CAE. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
A flight from FLO to CAE with a layover takes around 3 hours 30 minutes, with the route covering approximately 82 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
Select the "Business class" and "First class" filters when looking for FLO to CAE flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) flight with Expedia?
It's easy to earn miles on a Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbia from Florence Regional (FLO)?
If you're planning to travel to Columbia from Florence Regional (FLO), you can fly typically into Columbia Regional (COU) Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT) before reaching Columbia. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) at the last minute?
Typically, booking a last minute flight from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) flight and hotel package?
Securing a Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan)?
If you booked your Florence, SC (FLO-Florence Regional) to Columbia, SC (CAE-Columbia Metropolitan) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Florence Regional
Destination airport
Columbia Metropolitan
Roundtrip price
$497
Distance
81 mi

*Flight schedules are subject to change.

*Available to One Key members.

 

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