$239 Cheap Flights from Florence (FLO) to Columbia (CAE)

View $239 flight on Sat, Mar 28, 2026Opens in a new window

Popular airlines from Florence, SC (FLO-Florence Regional) to Columbia Metropolitan Airport (CAE)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Florence to Columbia (FLO-CAE)

Prices were available within the past 7 days and start at $239 for one-way flights and $482 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$482 Roundtrip, found 6 days ago
$482
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $482 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$623 Roundtrip, found 6 days ago
$623
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $623 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$645 Roundtrip, found 6 days ago
$645
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $645 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$646 Roundtrip, found 6 days ago
$646
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $646 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$701 Roundtrip, found 6 days ago
$701
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $701 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$727 Roundtrip, found 6 days ago
$727
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $727 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$746 Roundtrip, found 6 days ago
$746
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $746 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$746 Roundtrip, found 6 days ago
$746
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $746 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$768 Roundtrip, found 6 days ago
$768
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $768 found 6 days ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
FLO
Florence
CAE
Columbia
$791 Roundtrip, found 6 days ago
$791
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 23 from Florence to Columbia, returning Sun, Apr 26, priced at $791 found 6 days ago

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Frequently asked questions

How much does a flight from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE) cost?
Get a cheap one-way flight from $239 or cheap return flight from $482 from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE)?
The cheapest month to fly from FLO to CAE is April, when demand is low. Off-peak season is usually when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from FLO to CAE. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE)?
There aren't any daily nonstop flights departing from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from FLO to CAE?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary depending on a range of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE)?
To arrive at Columbia Metropolitan Airport (CAE) without delays, opt for a flight that leaves Florence Regional Airport (FLO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE) last-minute?
Booking your ticket from FLO to CAE right before your trip is usually more expensive. But if you're flexible with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a FLO to CAE flight and hotel package?
You'll typically save money by securing a FLO to CAE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your ideal flights and accommodations, you can add extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Florence Regional Airport (FLO) to Columbia Metropolitan Airport (CAE)?
Usually, it's possible to cancel or reschedule your FLO to CAE flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Florence Regional
Destination airport
Columbia Metropolitan
Roundtrip price
$482
Distance
81 mi

Book with confidence

Florence to Columbia Flights

The cheapest times to fly from Florence to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to Columbia are during the month of April. You can find some of the cheapest flights from Florence to Columbia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to Columbia

Sunday is one of the best days to book for cheap flights from Florence to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to Columbia in 2026. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Florence to Columbia Flights

*Flight schedules are subject to change.

Explore a world of travel with Expedia

*Available to One Key members.