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$274 Cheap Flights from Moline (MLI) to Lafayette (LFT)

View $274 flight on Fri, Sep 25, 2026Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Lafayette Regional Airport (LFT)

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Cheap Flights from Moline to Lafayette (MLI-LFT)

Prices were available within the past 7 days and start at $274 for one-way flights and $668 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Sep 4 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$668 Roundtrip, found 4 hours ago
$668
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Sep 4 from Moline to Lafayette, returning Mon, Sep 7, priced at $668 found 4 hours ago
American Airlines
Thu, Sep 3 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$728 Roundtrip, just found
$728
Roundtrip
just found
Select American Airlines flight, departing Thu, Sep 3 from Moline to Lafayette, returning Mon, Sep 7, priced at $728 just found
American Airlines
Fri, Sep 4 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$746 Roundtrip, found 4 hours ago
$746
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Sep 4 from Moline to Lafayette, returning Mon, Sep 7, priced at $746 found 4 hours ago
American Airlines
Fri, Sep 4 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$760 Roundtrip, found 4 hours ago
$760
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Sep 4 from Moline to Lafayette, returning Mon, Sep 7, priced at $760 found 4 hours ago
Delta
Thu, Sep 3 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$774 Roundtrip, just found
$774
Roundtrip
just found
Select Delta flight, departing Thu, Sep 3 from Moline to Lafayette, returning Mon, Sep 7, priced at $774 just found
American Airlines
Fri, Sep 4 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$791 Roundtrip, found 4 hours ago
$791
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Sep 4 from Moline to Lafayette, returning Mon, Sep 7, priced at $791 found 4 hours ago
American Airlines
Fri, Sep 4 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$796 Roundtrip, found 4 hours ago
$796
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Sep 4 from Moline to Lafayette, returning Mon, Sep 7, priced at $796 found 4 hours ago
American Airlines
Thu, Sep 3 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$820 Roundtrip, just found
$820
Roundtrip
just found
Select American Airlines flight, departing Thu, Sep 3 from Moline to Lafayette, returning Mon, Sep 7, priced at $820 just found
United
Thu, Sep 3 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$821 Roundtrip, just found
$821
Roundtrip
just found
Select United flight, departing Thu, Sep 3 from Moline to Lafayette, returning Mon, Sep 7, priced at $821 just found
Delta
Thu, Sep 3 - Mon, Sep 7
MLI
Moline
LFT
Lafayette
$834 Roundtrip, just found
$834
Roundtrip
just found
Select Delta flight, departing Thu, Sep 3 from Moline to Lafayette, returning Mon, Sep 7, priced at $834 just found

Frequently asked questions

How much does a flight from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) cost?
You can find cheap one-way flights from $274 and cheap return flights from $668 Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) with Expedia. One-way flights typically cost between $405 and $1017, and return flights often range between $342 and $1245. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
The cheapest month to fly from MLI to LFT is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
Enter MLI to LFT and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Quad City Intl. (MLI) to Lafayette Regional (LFT) with return tickets starting from around $270. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
To find a cheap flight from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
The earliest flight from Moline (MLI) to Lafayette (LFT) generally departs at around 5:45 AM, with American Airlines providing this service. This seasonal route is active in June and July, giving you a head start on your trip to Louisiana. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
The most popular departure times for flights from Moline, IL (MLI) to Lafayette, LA (LFT) are between 9am and 12pm. About 41% of passengers prefer this time window. Many major carriers, including AA and UA, offer flights during this window. This timing is ideal as it allows you to travel during the day, making your arrival more convenient.
How long does it take to fly from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
A flight from MLI to LFT with a layover takes around 5 hours, with the route covering approximately 782 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
Select the "Business class" and "First class" filters when looking for MLI to LFT flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) flight with Expedia?
It's easy to earn miles on a Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Lafayette from Quad City Intl. (MLI)?
If you're planning to travel to Lafayette from Quad City Intl. (MLI), you can fly into Lafayette Regional (LFT) Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN) before reaching Lafayette. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) at the last minute?
Typically, booking a last minute flight from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) flight and hotel package?
Securing a Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) Lafayette Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional)?
If you booked your Moline, IL (MLI-Quad City Intl.) to Lafayette, LA (LFT-Lafayette Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Quad City Intl.
Destination airport
Lafayette Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$667
Distance
781 mi

Book with confidence

Moline to Lafayette Flights

The cheapest times to fly from Moline to Lafayette

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to Lafayette are during the month of September. You can find some of the cheapest flights from Moline to Lafayette with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to Lafayette

Sunday is one of the best days to book for cheap flights from Moline to Lafayette: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to Lafayette

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to Lafayette in 2026. You can also book with separate airlines for your outbound and return journeys, from $274 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to Lafayette flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to Lafayette airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Moline to Lafayette Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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