$114 Cheap Flights from Palermo (PMO) to Brussels (BRU)

View $114 flight on Fri, Nov 7, 2025Opens in a new window

Popular airlines from Punta Raisi Airport (PMO) to Brussels Airport (BRU)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Palermo to Brussels (PMO-BRU)

Prices were available within the past 7 days and start at $114 for one-way flights and $197 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Swiss International Air Lines
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$197 Roundtrip, found 11 hours ago
$197
Roundtrip
found 11 hours ago
Select Swiss International Air Lines flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $197 found 11 hours ago
Swiss International Air Lines
Thu, Sep 18 - Sun, Sep 21
PMO
Palermo
BRU
Brussels
$217 Roundtrip, found 19 hours ago
$217
Roundtrip
found 19 hours ago
Select Swiss International Air Lines flight, departing Thu, Sep 18 from Palermo to Brussels, returning Sun, Sep 21, priced at $217 found 19 hours ago
Austrian Airlines
Thu, Sep 18 - Sun, Sep 21
PMO
Palermo
BRU
Brussels
$218 Roundtrip, found 19 hours ago
$218
Roundtrip
found 19 hours ago
Select Austrian Airlines flight, departing Thu, Sep 18 from Palermo to Brussels, returning Sun, Sep 21, priced at $218 found 19 hours ago
Swiss International Air Lines
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$238 Roundtrip, found 11 hours ago
$238
Roundtrip
found 11 hours ago
Select Swiss International Air Lines flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $238 found 11 hours ago
Swiss International Air Lines
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$239 Roundtrip, found 11 hours ago
$239
Roundtrip
found 11 hours ago
Select Swiss International Air Lines flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $239 found 11 hours ago
Lufthansa
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$241 Roundtrip, found 11 hours ago
$241
Roundtrip
found 11 hours ago
Select Lufthansa flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $241 found 11 hours ago
Swiss International Air Lines
Fri, Aug 15 - Thu, Aug 21
PMO
Palermo
BRU
Brussels
$241 Roundtrip, found 1 day ago
$241
Roundtrip
found 1 day ago
Select Swiss International Air Lines flight, departing Fri, Aug 15 from Palermo to Brussels, returning Thu, Aug 21, priced at $241 found 1 day ago
ITA Airways
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$243 Roundtrip, found 11 hours ago
$243
Roundtrip
found 11 hours ago
Select ITA Airways flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $243 found 11 hours ago
ITA Airways
Thu, Sep 18 - Wed, Sep 24
PMO
Palermo
BRU
Brussels
$244 Roundtrip, found 11 hours ago
$244
Roundtrip
found 11 hours ago
Select ITA Airways flight, departing Thu, Sep 18 from Palermo to Brussels, returning Wed, Sep 24, priced at $244 found 11 hours ago
Brussels Airlines
Thu, Sep 11 - Mon, Sep 15
PMO
Palermo
BRU
Brussels
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select Brussels Airlines flight, departing Thu, Sep 11 from Palermo to Brussels, returning Mon, Sep 15, priced at $297 found 2 days ago
Flights from Palermo (PMO) to Charleroi (CRL)
Origin airport
Punta Raisi
Destination airport
Brussels South Charleroi
Airlines serving
Austrian Airlines, Brussels Airlines, ITA Airways, Lufthansa, Swiss International Air Lines
Roundtrip price
$192
Distance
948 mi
Average flight time
2 hours 55 mins

Palermo to Brussels Flights

The cheapest times to fly from Palermo to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Palermo to Brussels are during the month of September. You can find some of the cheapest flights from Palermo to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Palermo to Brussels

Sunday is one of the best days to book for cheap flights from Palermo to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Palermo to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Palermo to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $114 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Palermo to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Palermo to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU) cost?
Discover the latest flight deals from PMO to BRU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PMO to BRU?
The cheapest flights from PMO to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PMO to BRU?
With prices starting from $282 for a one-way journey from PMO to BRU, TUI fly is currently the cheapest airline on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PMO on September 15 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU)?
There are no daily direct flights available from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from PMO to BRU?
Typically you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from PMO to BRU?
Neos has the strongest track record for on-time direct flights from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU), with an on-time score of 100%. Use the Expedia App to view your journey status before you jet off and receive notifications about any trip changes.
What is the best time to fly from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU)?
Opt for a flight from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU) that leaves before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Brussels from Punta Raisi Airport (PMO)?
Explore your flight options from Punta Raisi Airport (PMO) to Brussels South Charleroi Airport (CRL). This is the only Brussels airport you can touch down at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU) last-minute?
Waiting until just before your trip to book your flight from PMO to BRU generally means paying more. While it's possible to find some last-minute deals, they aren't always guaranteed. Be flexible with your travel plans for a better chance of getting a bargain.
Is it cheaper to book a PMO to BRU flight and hotel package?
Compared with arranging flights and hotels separately, booking a PMO to BRU flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place takes the hassle out of planning your trip. Simply pick your flights and select from our extensive range of hotels, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Punta Raisi Airport (PMO) to Brussels - National Airport (BRU)?
In most instances, you're able to reschedule or cancel your PMO to BRU flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like more details, visit our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.