$428 Cheap Flights from Roanoke (ROA) to Brussels (BRU)

View $428 flight on Fri, Nov 28, 2025Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Brussels Airport (BRU)

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Cheap Flights from Roanoke to Brussels (ROA-BRU)

Prices were available within the past 7 days and start at $428 for one-way flights and $661 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Fri, Nov 28 - Fri, Dec 5
ROA
Roanoke
BRU
Brussels
$661 Roundtrip, found 3 days ago
$661
Roundtrip
found 3 days ago
Select Air Canada flight, departing Fri, Nov 28 from Roanoke to Brussels, returning Fri, Dec 5, priced at $661 found 3 days ago
United
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
BRU
Brussels
$675 Roundtrip, found 4 days ago
$675
Roundtrip
found 4 days ago
Select United flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $675 found 4 days ago
Air Canada
Fri, Apr 10 - Wed, Apr 29
ROA
Roanoke
BRU
Brussels
$680 Roundtrip, found 4 days ago
$680
Roundtrip
found 4 days ago
Select Air Canada flight, departing Fri, Apr 10 from Roanoke to Brussels, returning Wed, Apr 29, priced at $680 found 4 days ago
United
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
BRU
Brussels
$685 Roundtrip, found 4 days ago
$685
Roundtrip
found 4 days ago
Select United flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $685 found 4 days ago
United
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
BRU
Brussels
$686 Roundtrip, found 4 days ago
$686
Roundtrip
found 4 days ago
Select United flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $686 found 4 days ago
United
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
BRU
Brussels
$688 Roundtrip, found 4 days ago
$688
Roundtrip
found 4 days ago
Select United flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $688 found 4 days ago
Air Canada
Fri, Apr 10 - Wed, Apr 29
ROA
Roanoke
BRU
Brussels
$689 Roundtrip, found 4 days ago
$689
Roundtrip
found 4 days ago
Select Air Canada flight, departing Fri, Apr 10 from Roanoke to Brussels, returning Wed, Apr 29, priced at $689 found 4 days ago
KLM
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
BRU
Brussels
$793 Roundtrip, found 4 days ago
$793
Roundtrip
found 4 days ago
Select KLM flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $793 found 4 days ago
Delta
Mon, Sep 1 - Thu, Sep 11
ROA
Roanoke
ZYR
Brussels
$803 Roundtrip, found 4 days ago
$803
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Sep 1 from Roanoke to Brussels, returning Thu, Sep 11, priced at $803 found 4 days ago
Lufthansa
Fri, Feb 27 - Fri, Mar 6
ROA
Roanoke
BRU
Brussels
$855 Roundtrip, found 1 hour ago
$855
Roundtrip
found 1 hour ago
Select Lufthansa flight, departing Fri, Feb 27 from Roanoke to Brussels, returning Fri, Mar 6, priced at $855 found 1 hour ago
Flights from Roanoke (ROA) to Brussels (BRU)
Origin airport
Roanoke Regional
Destination airport
Brussels - National
Roundtrip price
$660
Distance
4058 mi

Roanoke to Brussels Flights

The cheapest times to fly from Roanoke to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Brussels are during the month of November. You can find some of the cheapest flights from Roanoke to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Brussels

Sunday is one of the best days to book for cheap flights from Roanoke to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $428 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU) cost?
Discover the latest flight deals from ROA to BRU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ROA to BRU?
The cheapest flights from ROA to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from ROA to BRU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from ROA to BRU. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU)?
You'll need to book a flight with a layover if you're traveling from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from ROA to BRU?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU)?
To avoid possible delays on the Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU) route, aim to fly before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU) last-minute?
Holding off until right before your break to book a ticket from ROA to BRU often results in higher prices. While you may come across some last-minute deals, they're not always guaranteed. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a ROA to BRU flight and hotel package?
Booking a ROA to BRU flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our extensive range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to Brussels - National Airport (BRU)?
In most instances, you can modify or cancel your ROA to BRU flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need further details, go to our Customer Service portal.

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*Available to One Key members.