A coastal town with historic buildings, a marina with boats, and clear blue waters.

$513 Cheap Flights from Roanoke (ROA) to Palermo (PMO)

View $513 flight on Sun, Oct 25, 2026Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)

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Cheap Flights from Roanoke to Palermo (ROA-PMO)

Prices were available within the past 7 days and start at $513 for one-way flights and $1,014 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,014 Roundtrip, found 1 day ago
$1,014
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,014 found 1 day ago
United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,015 Roundtrip, found 1 day ago
$1,015
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,015 found 1 day ago
United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,018 Roundtrip, found 1 day ago
$1,018
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,018 found 1 day ago
United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,020 Roundtrip, found 1 day ago
$1,020
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,020 found 1 day ago
United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,021 Roundtrip, found 1 day ago
$1,021
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,021 found 1 day ago
United
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,064 Roundtrip, found 1 day ago
$1,064
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,064 found 1 day ago
Lufthansa
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,407 Roundtrip, found 1 day ago
$1,407
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,407 found 1 day ago
Brussels Airlines
Sun, Oct 25 - Sun, Nov 1
ROA
Roanoke
PMO
Palermo
$1,833 Roundtrip, found 1 day ago
$1,833
Roundtrip
found 1 day ago
Select Brussels Airlines flight, departing Sun, Oct 25 from Roanoke to Palermo, returning Sun, Nov 1, priced at $1,833 found 1 day ago
Air France
Mon, Sep 28 - Sat, Oct 3
ROA
Roanoke
PMO
Palermo
$2,165 Roundtrip, found 1 hour ago
$2,165
Roundtrip
found 1 hour ago
Select Air France flight, departing Mon, Sep 28 from Roanoke to Palermo, returning Sat, Oct 3, priced at $2,165 found 1 hour ago
KLM
Mon, Sep 28 - Sat, Oct 3
ROA
Roanoke
PMO
Palermo
$2,421 Roundtrip, found 1 hour ago
$2,421
Roundtrip
found 1 hour ago
Select KLM flight, departing Mon, Sep 28 from Roanoke to Palermo, returning Sat, Oct 3, priced at $2,421 found 1 hour ago

Frequently asked questions

How much does a flight from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) cost?
You can find cheap one-way flights from $513 and cheap return flights from $1,014 Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) with Expedia. Return flights typically cost between $859 and $1722. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
The cheapest month to fly from ROA to PMO is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
Enter ROA to PMO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
Delta is one of the cheapest airlines offering connecting flights from Roanoke, VA (ROA) to Palermo (PMO), with round-trip tickets starting from around $859, with a layover in Hartsfield-Jackson Atlanta Intl. (ATL). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
To find a cheap flight from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
The earliest flight from Roanoke (Roanoke Regional) to Palermo (Punta Raisi) usually departs at around 6:00 AM. This seasonal service is operated by Delta and ITA Airways, allowing you to start your Italian adventure early. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
You'll usually find the most flights from Roanoke Regional (ROA) to Punta Raisi (PMO) on a Friday, with around 20 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United, Delta, and American Airlines.
What are the most popular departure times for flights from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
The most popular departure times for flights from Roanoke, VA (ROA) to Palermo (PMO) are in the late morning, from 9am to 12pm. About 31% of passengers prefer this time window. Many major carriers, including Delta Airlines and United Airlines, offer flights during this window. This timing works well because it allows you to travel comfortably without rushing in the early hours.
How long does it take to fly from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
Flying from ROA to PMO with a connection usually takes about 21 hours 20 minutes, traveling roughly 4,840 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
Select the "Business class" and "First class" filters when looking for ROA to PMO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) flight with Expedia?
It's easy to earn miles on a Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Palermo from Roanoke Regional (ROA)?
If you're planning to travel to Palermo from Roanoke Regional (ROA), you can fly typically into Punta Raisi (PMO) Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Washington Dulles Intl. (IAD), O'Hare Intl. (ORD) before reaching Palermo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) at the last minute?
Typically, booking a last minute flight from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) flight and hotel package?
Securing a Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi)?
If you booked your Roanoke, VA (ROA-Roanoke Regional) to Palermo (PMO-Punta Raisi) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Roanoke Regional
Destination airport
Punta Raisi
Airlines serving
Air France, Brussels Airlines, KLM, Lufthansa, United
Roundtrip price
$1,013
Distance
4839 mi

Book with confidence

Roanoke to Palermo Flights

The cheapest times to fly from Roanoke to Palermo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Palermo are during the month of October. You can find some of the cheapest flights from Roanoke to Palermo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Palermo

Sunday is one of the best days to book for cheap flights from Roanoke to Palermo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Palermo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Palermo in 2026. You can also book with separate airlines for your outbound and return journeys, from $513 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Palermo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Palermo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Roanoke to Palermo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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