$143 Cheap Flights from Fort Myers (RSW) to San Francisco (SFO)

View $143 flight on Tue, Dec 9, 2025Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Fort Myers to San Francisco (RSW-SFO)

Prices were available within the past 7 days and start at $143 for one-way flights and $147 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Nov 13 - Sat, Nov 15
RSW
Fort Myers
SFO
San Francisco
$147 Roundtrip, found 2 days ago
$147
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Fort Myers to San Francisco, returning Sat, Nov 15, priced at $147 found 2 days ago
Frontier Airlines
Thu, Nov 20 - Thu, Nov 27
RSW
Fort Myers
SFO
San Francisco
$211 Roundtrip, found 13 hours ago
$211
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Thu, Nov 20 from Fort Myers to San Francisco, returning Thu, Nov 27, priced at $211 found 13 hours ago
JetBlue Airways
Tue, Dec 9 - Sun, Dec 14
RSW
Fort Myers
SFO
San Francisco
$221 Roundtrip, just found
$221
Roundtrip
just found
Select JetBlue Airways flight, departing Tue, Dec 9 from Fort Myers to San Francisco, returning Sun, Dec 14, priced at $221 just found
Southwest Airlines
Sun, Jan 11 - Sun, Jan 18
RSW
Fort Myers
SFO
San Francisco
$228 Roundtrip, found 5 hours ago
$228
Roundtrip
found 5 hours ago
Select Southwest Airlines flight, departing Sun, Jan 11 from Fort Myers to San Francisco, returning Sun, Jan 18, priced at $228 found 5 hours ago
Alaska Airlines
Sat, Dec 6 - Sun, Dec 7
RSW
Fort Myers
SFO
San Francisco
$229 Roundtrip, found 23 hours ago
$229
Roundtrip
found 23 hours ago
Select Alaska Airlines flight, departing Sat, Dec 6 from Fort Myers to San Francisco, returning Sun, Dec 7, priced at $229 found 23 hours ago
Southwest Airlines
Tue, Dec 9 - Sun, Dec 14
RSW
Fort Myers
SFO
San Francisco
$233 Roundtrip, just found
$233
Roundtrip
just found
Select Southwest Airlines flight, departing Tue, Dec 9 from Fort Myers to San Francisco, returning Sun, Dec 14, priced at $233 just found
Southwest Airlines
Wed, Dec 3 - Sun, Dec 7
RSW
Fort Myers
SFO
San Francisco
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Dec 3 from Fort Myers to San Francisco, returning Sun, Dec 7, priced at $234 found 1 day ago
Frontier Airlines
Thu, Nov 6 - Sat, Nov 15
RSW
Fort Myers
SFO
San Francisco
$236 Roundtrip, found 2 days ago
$236
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Fort Myers to San Francisco, returning Sat, Nov 15, priced at $236 found 2 days ago
Southwest Airlines
Tue, Dec 9 - Sun, Dec 14
RSW
Fort Myers
SFO
San Francisco
$238 Roundtrip, just found
$238
Roundtrip
just found
Select Southwest Airlines flight, departing Tue, Dec 9 from Fort Myers to San Francisco, returning Sun, Dec 14, priced at $238 just found
Delta
Wed, Dec 3 - Sun, Dec 7
RSW
Fort Myers
SFO
San Francisco
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Dec 3 from Fort Myers to San Francisco, returning Sun, Dec 7, priced at $254 found 1 day ago

Find the cheapest month to fly from Fort Myers (RSW) to San Francisco (SFO)

September is typically the cheapest month to fly

From $158 - $416 per traveler.

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Norman Y. Mineta San Jose Intl. SJC. Average driving time to city center is 50 minutes. Flights from $454
SJC
Norman Y. Mineta San Jose Intl.
Average driving time to city center50 min
Flights from $454
Select flight to Oakland Intl. OAK. Average driving time to city center is 26 minutes. Flights from $628
OAK
Oakland Intl.
Average driving time to city center26 min
Flights from $628

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO) cost?
Snag a cheap one-way flight from $143 or cheap return flight from $147 from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)?
The cheapest month to fly from RSW to SFO is November, when there's less demand. Off-peak months are often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)?
To find the cheapest airline that'll fly you from RSW to SFO, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)?
You'll need to take a flight with a layover when traveling from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO). There are no daily direct flights on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from RSW to SFO?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)?
To reach San Francisco Intl. Airport (SFO) without delays, pick a flight that leaves from Southwest Florida Intl. Airport (RSW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO) last-minute?
Holding off until right before your break to book a flight from RSW to SFO generally means paying more. While you may find some last-minute deals, there's no guarantee. Allow some flexibility in your schedule for a better chance of landing a bargain.
Is it cheaper to book a RSW to SFO flight and hotel package?
Booking a RSW to SFO flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our extensive range of hotels and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to San Francisco Intl. Airport (SFO)?
Typically, you can modify or cancel your RSW to SFO flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you'd like further information, head to our Customer Service portal.

Travel information

Origin airport
Southwest Florida Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, JetBlue Airways, Southwest Airlines, Sun Country Airlines, United
Roundtrip price
$147
Distance
2477 mi

Book with confidence

Fort Myers to San Francisco Flights

The cheapest times to fly from Fort Myers to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to San Francisco are during the month of November. You can find some of the cheapest flights from Fort Myers to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to San Francisco

Sunday is one of the best days to book for cheap flights from Fort Myers to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $143 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Fort Myers to San Francisco Flights

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