$681 Cheap Flights from Santiago (SCL) to Prague (PRG)

View $681 flight on Tue, Nov 4, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Vaclav Havel Airport (PRG)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Santiago to Prague (SCL-PRG)

Prices were available within the past 7 days and start at $681 for one-way flights and $1,078 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Tue, Nov 25 - Tue, Dec 2
SCL
Santiago
PRG
Prague
$1,078 Roundtrip, found 5 days ago
$1,078
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Nov 25 from Santiago to Prague, returning Tue, Dec 2, priced at $1,078 found 5 days ago
Air Canada
Tue, Nov 25 - Tue, Dec 2
SCL
Santiago
PRG
Prague
$1,095 Roundtrip, found 5 days ago
$1,095
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Nov 25 from Santiago to Prague, returning Tue, Dec 2, priced at $1,095 found 5 days ago
LATAM Airlines Group
Sat, Nov 1 - Mon, Nov 17
SCL
Santiago
PRG
Prague
$1,128 Roundtrip, found 11 hours ago
$1,128
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Sat, Nov 1 from Santiago to Prague, returning Mon, Nov 17, priced at $1,128 found 11 hours ago
LATAM Airlines Group
Sat, Nov 1 - Mon, Nov 17
SCL
Santiago
PRG
Prague
$1,160 Roundtrip, found 11 hours ago
$1,160
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Sat, Nov 1 from Santiago to Prague, returning Mon, Nov 17, priced at $1,160 found 11 hours ago
Air Canada
Tue, Nov 25 - Tue, Dec 2
SCL
Santiago
PRG
Prague
$1,178 Roundtrip, found 5 days ago
$1,178
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Nov 25 from Santiago to Prague, returning Tue, Dec 2, priced at $1,178 found 5 days ago
British Airways
Tue, Jun 2 - Fri, Jun 12
SCL
Santiago
PRG
Prague
$1,192 Roundtrip, found 2 hours ago
$1,192
Roundtrip
found 2 hours ago
Select British Airways flight, departing Tue, Jun 2 from Santiago to Prague, returning Fri, Jun 12, priced at $1,192 found 2 hours ago
Air Canada
Tue, Nov 25 - Tue, Dec 2
SCL
Santiago
PRG
Prague
$1,195 Roundtrip, found 5 days ago
$1,195
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Nov 25 from Santiago to Prague, returning Tue, Dec 2, priced at $1,195 found 5 days ago
LATAM Airlines Group
Tue, Nov 25 - Tue, Dec 2
SCL
Santiago
PRG
Prague
$1,197 Roundtrip, found 5 days ago
$1,197
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 25 from Santiago to Prague, returning Tue, Dec 2, priced at $1,197 found 5 days ago
Iberia
Tue, Jun 2 - Fri, Jun 12
SCL
Santiago
PRG
Prague
$1,210 Roundtrip, found 2 hours ago
$1,210
Roundtrip
found 2 hours ago
Select Iberia flight, departing Tue, Jun 2 from Santiago to Prague, returning Fri, Jun 12, priced at $1,210 found 2 hours ago
Turkish Airlines
Fri, Jul 3 - Sun, Jul 26
SCL
Santiago
PRG
Prague
$1,226 Roundtrip, found 21 hours ago
$1,226
Roundtrip
found 21 hours ago
Select Turkish Airlines flight, departing Fri, Jul 3 from Santiago to Prague, returning Sun, Jul 26, priced at $1,226 found 21 hours ago
Flights from Santiago (SCL) to Prague (PRG)
Origin airport
Arturo Merino Benitez
Destination airport
Vaclav Havel
Airlines serving
Air Canada, Air France, American Airlines, British Airways, Delta, Iberia, KLM, LATAM Airlines Group, Turkish Airlines, United
Roundtrip price
$1,078
Distance
7745 mi

Santiago to Prague Flights

The cheapest times to fly from Santiago to Prague

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Prague are during the month of November. You can find some of the cheapest flights from Santiago to Prague with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Prague

Sunday is one of the best days to book for cheap flights from Santiago to Prague: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Prague

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Prague in 2025. You can also book with separate airlines for your outbound and return journeys, from $681 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Prague flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Prague airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG) cost?
Grab a cheap one-way flight from $681 or cheap return flight from $1,078 from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG)?
November is the least expensive month to fly from SCL to PRG. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll fly you from SCL to PRG. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG)?
Nonstop flights from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SCL to PRG?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG)?
Select a flight from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG) that takes off before 3 PM to reduce the likelihood of delays. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG) last-minute?
Waiting until just before your trip to book a ticket from SCL to PRG often results in higher prices. Although you may find some last-minute offers, they aren't always guaranteed. Be flexible with your itinerary to maximize your chances of landing a bargain.
Is it cheaper to book a SCL to PRG flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to PRG flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one easy place takes the hassle out of planning your trip. Just pick your flights and select from our extensive range of stays, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Vaclav Havel Airport (PRG)?
It's usually possible to cancel or reschedule your SCL to PRG flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.