$143 Cheap Flights from Santander (SDR) to Lyon (LYS)

View $143 flight on Wed, Apr 22, 2026Opens in a new window

Popular airlines from Santander (SDR) to Saint-Exupery Airport (LYS)

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Cheap Flights from Santander to Lyon (SDR-LYS)

Prices were available within the past 7 days and start at $143 for one-way flights and $412 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$412 Roundtrip, found 1 day ago
$412
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $412 found 1 day ago
Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$420 Roundtrip, found 1 day ago
$420
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $420 found 1 day ago
Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$451 Roundtrip, found 1 day ago
$451
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $451 found 1 day ago
Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$459 Roundtrip, found 1 day ago
$459
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $459 found 1 day ago
Iberia
Mon, Dec 29 - Sat, Jan 3
SDR
Santander
LYS
Lyon
$470 Roundtrip, found 5 days ago
$470
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Dec 29 from Santander to Lyon, returning Sat, Jan 3, priced at $470 found 5 days ago
Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$510 Roundtrip, found 1 day ago
$510
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $510 found 1 day ago
Iberia
Mon, Dec 29 - Sat, Jan 3
SDR
Santander
LYS
Lyon
$513 Roundtrip, found 5 days ago
$513
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Dec 29 from Santander to Lyon, returning Sat, Jan 3, priced at $513 found 5 days ago
Iberia
Mon, Dec 29 - Sat, Jan 3
SDR
Santander
LYS
Lyon
$529 Roundtrip, found 5 days ago
$529
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Dec 29 from Santander to Lyon, returning Sat, Jan 3, priced at $529 found 5 days ago
Iberia
Tue, Dec 16 - Tue, Dec 23
SDR
Santander
LYS
Lyon
$559 Roundtrip, found 1 day ago
$559
Roundtrip
found 1 day ago
Select Iberia flight, departing Tue, Dec 16 from Santander to Lyon, returning Tue, Dec 23, priced at $559 found 1 day ago
Iberia
Mon, Dec 29 - Sat, Jan 3
SDR
Santander
LYS
Lyon
$580 Roundtrip, found 5 days ago
$580
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Dec 29 from Santander to Lyon, returning Sat, Jan 3, priced at $580 found 5 days ago

Frequently asked questions

How much does a flight from Santander Airport (SDR) to Saint-Exupery Airport (LYS) cost?
Secure a cheap one-way flight from $143 or cheap return flight from $412 from Santander Airport (SDR) to Saint-Exupery Airport (LYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Santander Airport (SDR) to Saint-Exupery Airport (LYS)?
Flying in December can help you save, as it's the cheapest month for flights between SDR and LYS. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Santander Airport (SDR) to Saint-Exupery Airport (LYS)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from SDR to LYS. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Santander Airport (SDR) to Saint-Exupery Airport (LYS)?
You'll need to hop on a flight with a layover when traveling from Santander Airport (SDR) to Saint-Exupery Airport (LYS). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from SDR to LYS?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Santander Airport (SDR) to Saint-Exupery Airport (LYS)?
To reach Saint-Exupery Airport (LYS) on schedule, choose a flight that leaves from Santander Airport (SDR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Santander Airport (SDR) to Saint-Exupery Airport (LYS) last-minute?
Waiting until just before your trip to book a flight from SDR to LYS generally means paying more. While it's possible to find some last-minute deals, they aren't always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book a SDR to LYS flight and hotel package?
Compared with arranging flights and hotels separately, booking a SDR to LYS flight and hotel package with Expedia could result in significant savings. What's more, having everything in one easy place takes the hassle out of planning your trip. Simply pick your flights and choose from our extensive range of stays, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Santander Airport (SDR) to Saint-Exupery Airport (LYS)?
If you reserved your SDR to LYS flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Origin airport
Santander
Destination airport
Saint-Exupery
Roundtrip price
$412
Distance
465 mi

Book with confidence

Santander to Lyon Flights

The cheapest times to fly from Santander to Lyon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santander to Lyon are during the month of December. You can find some of the cheapest flights from Santander to Lyon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santander to Lyon

Sunday is one of the best days to book for cheap flights from Santander to Lyon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santander to Lyon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santander to Lyon in 2025. You can also book with separate airlines for your outbound and return journeys, from $143 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santander to Lyon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santander to Lyon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santander to Lyon Flights

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