
Popular airlines from St. Louis Lambert Intl. Airport (STL) to Comayagua (XPL-Palmerola Intl.)
- American Airlines
American Airlines
- United
United
- Spirit Airlines
Spirit Airlines
- Copa
Copa
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Cheap Flights from St. Louis to Comayagua (STL-XPL)
Prices were available within the past 7 days and start at $110 for one-way flights and $296 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from St. Louis (STL) to Tegucigalpa (XPL)
May is typically the cheapest month to fly
Alternative airports near Tegucigalpa
Prices were available within the past 7 days. Prices and availability are subject to change.
Frequently asked questions
Travel information
Origin airport | Lambert-St. Louis Intl. |
|---|---|
Destination airport | Palmerola Intl. |
Airlines serving | American Airlines, Copa, Spirit Airlines, United |
Roundtrip price | $296 |
Distance | 1690 mi |
Book with confidence
St. Louis to Comayagua Flights
The cheapest times to fly from St. Louis to Comayagua
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Comayagua are during the month of January. You can find some of the cheapest flights from St. Louis to Comayagua with Expedia's search tool and vast selection of airlines.
The best time to book a flight from St. Louis to Comayagua
Sunday is one of the best days to book for cheap flights from St. Louis to Comayagua: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from St. Louis to Comayagua
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Comayagua in 2025. You can also book with separate airlines for your outbound and return journeys, from $110 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.