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4 Star Hotels in Florida Keys, FL

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Florida Keys Hotels

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Featured Florida Keys 4 Star Hotels

See all 390 Hotels in Florida Keys
Santa Maria Suites

Santa Maria Suites

1401 Simonton St, Key West
4.0 out of 5.0
4.8 out of 5 (365 reviews)
beautiful! Room was like an apartment rather than a hotel. Top notch all the way! I'm spoiled now - won't stay anywhere else.
  Jul 10, 2017

$399

$399
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Islamorada
4.0 out of 5.0
4.4 out of 5 (644 reviews)
WeddingWe had our wedding there. Went off without a flaw. Would do the same in a beartbeat. Thank you !
  Jul 16, 2017

$143

$143
Parrot Key Hotel & Resort

Parrot Key Hotel & Resort

2801 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.2 out of 5 (1,122 reviews)
I would recommend this hotel the location is great and the space of the bedrooms is perfect
  Jul 23, 2017

$169

$169
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.0 out of 5.0
4.5 out of 5 (462 reviews)
Nice hotel but staff could be a little better. Nice hotel on Route 1 and on the beach. Facilities are well maintained, but desk did not tell us they were putting us in a handicap room (not as nice as standard rooms) when they had standard rooms available. Facilities are nice, and well maintained. The Butterfly room is a very good restaurant, ...
  Jul 2, 2017

$349

$349
Southernmost Beach Resort

Southernmost Beach Resort

508 South St, Key West
4.0 out of 5.0
4.5 out of 5 (1,415 reviews)
Nice hotel with very helpful staffThe hotel staff was very kind. Our room was well kept. The beach was nice and the drinks by the pool were great!
  Jul 24, 2017

$199

$199
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Zero Duval St., Key West
4.0 out of 5.0
4.6 out of 5 (717 reviews)
Awesome location We went here for our honeymoon and we had a great time everything was amazing great service
  Jul 21, 2017

$229

$229
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
4.0 out of 5.0
4.4 out of 5 (630 reviews)
Perfect Location! The hotel is beautiful, and the staff exceeded my expectations! They were friendly and accommodating. They made every effort to make sure we had a fantastic stay. Floating in the water while my cocktails were served to me at the beach made me feel very pampered.
  Jul 22, 2017

$269

$269
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.0 out of 5.0
4.5 out of 5 (674 reviews)
Great hotel with beach access My two sons and I had a great experience from the time we arrived. The beach access was great. It was close to the marina with Mallory Square and Duvall street being just a quick walk.
  Jul 22, 2017

$229

$229
Little Palm Island Resort & Spa - A Noble House Resort

Little Palm Island Resort & Spa - A Noble House Resort

28500 Overseas Hwy, Little Torch Key
4.5 out of 5.0
4.9 out of 5 (23 reviews)
fabulous accommodation and staff...service is superb
  Jul 3, 2017

$790

$790
The Gardens Hotel

The Gardens Hotel

526 Angela Street, Key West
4.0 out of 5.0
4.8 out of 5 (115 reviews)
Best breakfast... Great location , friendly staff. Parking was limited
  Jul 9, 2017

$187

$187
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Florida Keys Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Florida Keys, Florida are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Florida Keys 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Florida Keys. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Florida Keys, Florida, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Florida Keys hotels offer everything your heart desires.