
Seneca Vacations from $402
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Your Seneca Vacation
Get ready to experience Seneca your way with a custom Seneca vacation package! Uncovering the best parts of this captivating city is made easier with a base in a neighborhood such as Loma Linda, which is great for golfing, among plenty of other things. Want to tour the sights but unsure where to start? Any trip to Seneca should include Bordertown Casino. Expedia is here to help you escape your daily routine. Tailor your vacation to Seneca to match your travel style, whatever that may be.
The Latest Seneca vacation packages
Price found within the past 48 hours. Click for updated prices.

Super 8 by Wyndham Joplin
Price was $446, price is now $402 per person
$402
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Joplin (JLN)
5.8/10  (523 reviews)
Room had an odor. Entrances to the building are not always secure. If they did close and lock, key card wouldn't unlock. Had to go to the front entrance.
Reviewed on Oct 30, 2025

Holiday Inn Express And Suites Joplin Southeast by IHG
Price was $602, price is now $527 per person
$527
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Joplin (JLN)
8.2/10 Very Good! (551 reviews)
The hotel was so clean and the staff was excellent. I enjoyed the fitness center. Everything was just so great! The breakfast was really wonderful and we were so happy with our stay.
Reviewed on Oct 27, 2025

Holiday Inn Joplin by IHG
Price was $563, price is now $493 per person
$493
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Joplin (JLN)
9/10 Wonderful! (476 reviews)
I stay here a couple of times a year and always have a nice stay. The rooms are clean, beds comfy and rooms are quiet. The staff are always very friendly and helpful.
Reviewed on Oct 28, 2025

Precious Hotel
Price was $487, price is now $429 per person
$429
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Joplin (JLN)
5.8/10  (87 reviews)
Handicap parking was a lot of walking.  Room looks fine.  To cold.  Was set for 64 degrees
Reviewed on Oct 30, 2025

Days Inn by Wyndham Joplin
Price was $472, price is now $421 per person
$421
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Des Moines (DSM) to Joplin (JLN)
7/10 Good! (1,007 reviews)
Manager is always so nice. Property is a bit dated, but comfortable and clean
Reviewed on Oct 30, 2025
Seneca Hotel Deals

La Quinta Inn & Suites by Wyndham Joplin
3320 S Range Line Rd, Joplin, MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $118 total per night from Nov 10 to Nov 11
$118 total
Nov 10 - Nov 11
Total with taxes and fees
8.8/10 Excellent! (1,410 reviews)
Will be back
Reviewed on Oct 30, 2025

Drury Inn & Suites Joplin
3601 S Range Line Rd, Joplin, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Nov 9 to Nov 10
$102 total
Nov 9 - Nov 10
Total with taxes and fees
9.2/10 Wonderful! (1,002 reviews)
It was awesome!!!
Reviewed on Oct 24, 2025

River Bend Casino & Hotel
100 Jackpot Place, Wyandotte, OK
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $81 total per night from Nov 3 to Nov 4
$81 total
Nov 3 - Nov 4
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
Staff both in the hotel and the casino are phenomenal people!! I would recommend this property to anyone coming through this area. In fact, as soon as my health insurance company approves my final surgery, we will be booking here again.
Reviewed on Oct 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Seneca Vacation Packages
Seneca Essential Information
| Language | English | 
|---|---|
| Currency | U.S dollars | 
| Closest Airport | Joplin Regional Airport (JLN) | 
| Population | 2,400 | 
| Top Sights | Bordertown Casino and Sandstone Gardens | 
More vacations you might like
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



















