Car Rental Mesa, CO

Search and Compare from Car Companies in Mesa

I have a discount code

Featured car rental suppliers

Compare from agencies

car suppliers logo

  • protection illustration

    Change your mind

    Penalty-free cancellation on many/select car rentals
  • trophy illustration

    Treat yourself

    One Key members save 10% or more on over 1 million car rentals
    Learn about One Key
  • package illustration

    Shop smart

    Compare car suppliers and package your flight, hotel, and car to save

Top Car Deals in Mesa

* Price found within the past 6 days. Click for updated prices.

Economy

Chevrolet Spark
  • 4 people
Mesa, Colorado, USA
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Mesa, Colorado, USA
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Mesa, Colorado, USA
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Mesa, Colorado, USA
Jeep Compass
SUV Jeep Compass

Don't see what you're looking for?

See all car rentals in Mesa
View all cars

What you need to know for your Mesa car rental

Reasons to book a car rental in and around Mesa

Renting a car in Mesa, Colorado, offers you the freedom to explore the area at your own pace. With a rental car, you can easily manage your luggage and create flexible travel plans, allowing you to visit attractions like High Country Orchards, located 15 miles away, or Island Lake, which is 12 miles from Mesa, perfect for outdoor and romantic experiences. Additionally, De Beque City Park, also 12 miles away, provides a great spot for eco-friendly outdoor family activities. The convenience of a rental car extends to nearby cities such as Molina, just 4 miles away, where you can discover more scenic spots like Cobbett Lake. A trip to Palisade, 12 miles from Mesa, allows you to explore the Mesa County Fairgrounds and the Western Colorado Botanical Gardens. If you're interested in adventure sports or skiing, having a car makes it easy to access locations like Collbran, 11 miles away, which features Grand Mesa National Forest. Overall, a rental car enhances your ability to enjoy Mesa and its surrounding attractions fully, whether you are traveling with family, seeking adventure, or looking for scenic beauty.

Where to stay around Mesa

  • Palisade: Located 12 miles from Mesa, Palisade is an excellent choice for those seeking adventure and outdoor experiences. Popular activities here include skiing and exploring nearby attractions such as the Mesa County Fairgrounds and the Western Colorado Botanical Gardens. In addition, Palisade offers a variety of dining options, particularly for wine enthusiasts, with numerous wineries and restaurants to enjoy.
  • Collbran: Situated 11 miles from Mesa, Collbran is a charming destination for outdoor lovers and adventure seekers. Its scenic landscapes feature recreational areas and national parks, making it ideal for activities like hiking and fishing. Key points of interest include the Grand Mesa National Forest and Cobbett Lake, both perfect for enjoying nature. Collbran also offers a selection of dining spots, including local wineries and restaurants.
  • Grand Mesa: Approximately 13 miles from Mesa, Grand Mesa is a village renowned for its outdoor and skiing opportunities. Visitors can explore the Grand Mesa National Forest and Island Lake, both offering stunning scenery and outdoor activities. This area is also home to various dining options, including breweries and wineries. Grand Mesa is particularly inviting for those looking to immerse themselves in nature's beauty.

10 tips to save on your car rental in and around Mesa

  1. Use filters to find the right car: Refine your search by selecting vehicle type and specific features. Whether you're looking for an SUV for extra room, a convertible for sunny days, or an economical car for budget-friendly travel, apply filters on Expedia to discover the perfect fit for your journey.
  2. Book in advance to help lower costs: Rental rates can vary based on demand, so it's advisable to secure your car well ahead of your trip. By booking early, you are more likely to secure lower prices and enjoy better availability, especially during peak travel seasons.
  3. Consider a smaller car for savings: Smaller vehicles typically come with lower rental rates and are easier to park in crowded areas. Mid-size cars offer a good balance of affordability, comfort, and fuel efficiency.
  4. Age guidelines: Drivers under 30 may encounter higher deposits or daily fees, and certain vehicle categories—such as SUVs or luxury models—might not be available. This can also apply to renters over 70. Always verify the age requirements prior to booking.
  5. Check fuel policies: Some rental agreements require a full-to-full fuel policy, meaning you must return the vehicle with a full tank to avoid additional fees. This is usually the most favorable option. Others may offer full-to-empty or prepaid fueling choices, which can also be acceptable. Just ensure you return the car empty in this scenario.
  6. Save on city and airport pickups: Picking up your rental car at airports often incurs an extra fee, but the added convenience may justify the cost.
  7. Know your payment options: Most car rental companies primarily accept credit cards for payment.
  8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provides peace of mind in case something unforeseen occurs during your trip. Adding car rental insurance during your Expedia booking is a straightforward process.
  9. Consider unlimited mileage: If you're planning lengthy road trips, seek out rentals that offer unlimited mileage to prevent additional charges.
  10. Bring your driver's license and ID: A valid driver's license is necessary to rent a vehicle.

Finding the cheapest car rentals in Mesa

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Mesa into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Mesa and provide you with a list of the cheapest options, with no added fees.

Renting a car in Mesa

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Mesa. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Mesa

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book .

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

We all love being rewarded

One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

Car Rental Information

Popular car types
SUV, Full Size, Economy
Car suppliers available
Our best deal of the day
Our second best deal of the day
Our third best deal of the day
From the airport to your hotel
Airport Transportation
From popular domestic and international airports
Airport Car Rentals

Frequently asked questions

How much is a rental car per day in Mesa?
The lowest daily rate for a rental car in Mesa within the past seven days was . In the comfort of your own set of wheels, it's easy to cruise to whichever sights are calling your name.
Can I rent a car from Grand Junction Regional Airport (GJT)?
You can choose from a great range of car rental outlets not far from the airport. Dollar, Avis and Budget are popular with travelers. Enterprise and Alamo are a couple of other reliable options.
What happens if I need to cancel my Mesa car reservation?
There are always times when even the best-laid plans go wrong. That's why we give a full refund on many prepaid reservations if you cancel six hours before picking up the car. Remember to double-check the rental agreement — in some cases it's not an option. Found nothing there? Our Customer Service Portal has more useful information.
Where can I go on a road trip from Mesa?
There's so much to do in Mesa, but head farther afield and you'll find more sightseeing magic. Book a set of wheels and you can roam around the greater area at your leisure. Add these awesome destinations to your to-do list:
  • Vail is 100 miles from Mesa. Notable tourist spots like Vail Ski Resort deserve to be high on your list here.
  • Situated 50 miles away, Glenwood Springs is also a favorite with travelers. Be sure to experience Glenwood Hot Springs while you're in town. It's one of the reasons people love visiting this vibrant city.
  • Visit Garden of the Gods to feel grounded in nature. Pack a picnic to enjoy or just recharge your batteries in the fresh air. From Mesa, it's about 180 miles away.
How do I find the best car rental deals in Mesa with Expedia?
Getting an awesome deal on your Mesa rental car is a piece of cake with Expedia. Choose your preferred car type, add some details and compare prices across top brands. Why not add flights and hotels to your booking? You'll unlock even bigger savings when you combine your bookings into a package.
How old do you have to be to rent a car in Mesa?
Rental car rules in Mesa require drivers to be at least 21. Are you a younger driver? Surcharges and restrictions may apply. Most rental providers impose what's known as a young driver surcharge, which is an extra fee to the car rental cost. Restrictions usually apply to the types of cars available to young people too. Age limits may differ between suppliers, so check before you book.
What do you need to rent a car in Mesa?
The main requirements are a valid driver's license and a credit card in the same name. Many car rental companies will offer you insurance, which is optional. But you may have to provide proof of alternative coverage if you opt out. Check with your supplier to avoid any hassles.
What is the cheapest car rental in Mesa?
With car rental prices starting as low as and a day in Mesa within the past seven days, you'll be driving off with your own amazing deal before long. These rates were available on Expedia, with a rental starting date within the next year. Prices and availability are subject to change and additional terms apply.
Can I rent a car for a month or longer in Mesa?
Yes. We partner with trusted companies that offer weekly and monthly rentals for all car types. Book one of our long-term car rental deals and discover every nook and cranny of Mesa — or far beyond!
Where can I find a Mesa car rental if I am younger than 25?
You'll need to investigate the age policy of the Mesa rental suppliers you're considering. If you're under 25 years old, be aware that some will charge additional costs. It's handy to know this before arriving at the desk so you can plan your budget accordingly. Every rental car company has its own terms and conditions for young drivers, so be sure to do your research.
What insurance should I choose for my car rental in Mesa?
It's a good idea to add collision protection while reserving your Mesa rental car with Expedia. This protects your ride against accident damage, theft and vandalism throughout your road trip. Offering up to $35,000 in primary coverage and 24-hour emergency assistance, you can take the wheel knowing you'll be covered in the event of a mishap. You can opt in to this insurance during the checkout process.

Explore a world of travel with Expedia