Photo by Isa

Search Vacation Homes in Cayos Zapatilla

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11
In one month
Jan 23 - Jan 25
In two months
Feb 20 - Feb 22

Our top choices for Cayos Zapatilla vacation homes

Exterior
Surfari Bocas

Vacation Home in Bocas del Toro

Surfari Bocas
2.5 star property
9.0 out of 10, Wonderful, (53)
"Super friendly and helpful checkin. Clean room, would stay again next time!"
United States
Troy
$40 nightly
The price is $44
Jan 6 - Jan 7, 2026
Total with taxes and fees
Surfari Bocas
1 bedroom, WiFi, bed sheets
Tranquil Waterfall Studio, Oceanfront with Jungle Hiking and Starlink

Vacation Home in Bocas del Toro

Tranquil Waterfall Studio, Oceanfront with Jungle Hiking and Starlink
$130 nightly
The price is $137
Dec 26 - Dec 27
Total with taxes and fees
Tranquil Waterfall Studio, Oceanfront with Jungle Hiking and Starlink
Beach
Fabulous 3-bedroom house with AC in Bocas del Toro

Vacation Home in Isla Colón

Fabulous 3-bedroom house with AC in Bocas del Toro
2.0 star property
10.0 out of 10, Exceptional, (1)
"Large comfortable home in the Big Creek area set in a lush tropical setting which is minutes walk to the beach. Enjoyed the serenity of the setting and was a short taxi ride to town. We saw a family of howler monkeys come close to the property daily which was a real treat.Lea was a great host and got us in contact with a reliable taxi service that used during our stay."
United States
Brad C.
$201 nightly
The price is $201
Dec 28 - Dec 29
Total with taxes and fees
Fabulous 3-bedroom house with AC in Bocas del Toro
Outdoor dining
Bocas Villas - Private Acqua Villas

Vacation Home in Bocas del Toro

Bocas Villas - Private Acqua Villas
8.8 out of 10, Excellent, (36)
"If you are looking for pure relaxation. This is the place. Would be nice to put in the ad that you have to take a boat to get anywhere. And they cost minimum of 20 dollars each way Internet is very spotty. And almost impossible when used by more than one person. "
United States
Daniel G.
$159 nightly
The price is $159
Jan 4 - Jan 5, 2026
Total with taxes and fees
Bocas Villas - Private Acqua Villas
Terrace/patio
Casa Piedra

Vacation Home in Tierra Oscura

Casa Piedra
3.5 star property
Casa Piedra
Outdoor dining
Casa del Cielo

Vacation Home in Bastimentos Island

Casa del Cielo
8.0 out of 10, Very Good, (2)
"The house has a fantastic view. What was not mentioned is that it is literally 97 steps to get to it. When it rains some of the path way is very muddy. One of the wooden steps is not attached. There are chickens and roosters all around which is entertaining except when the roosters start crowing at 2am. The neighbors blasted music outside of their houses every night we were there which lasted as late as 2am. It was a different house every night with sound equipment set up on the porch. There...
United States
Stacey S.
$198 nightly
The price is $198
Jan 5 - Jan 6, 2026
Total with taxes and fees
Casa del Cielo
Interior
Brand NEW Home Over on the Water

Vacation Home in Bocas del Toro

Brand NEW Home Over on the Water
8.6 out of 10, Excellent, (7)
"This was a unique and amazing place to stay.We loved it!! Lauren was an exceptional host from afar, and the people and places she suggested were all top notch, attentive, and wonderful. The house was so cool! Loved swimming off the front deck and so cool to pick up water taxi rides from our front door! Highly recommend this home for the adventurous types!"
United States
Enrique & Jody V.
$135 nightly
The price is $138
Jan 2 - Jan 3, 2026
Total with taxes and fees
Brand NEW Home Over on the Water
Outdoor dining
Bocas Villas - Private Acqua Villas

Vacation Home in Punta Caracol

Bocas Villas - Private Acqua Villas
9.0 out of 10, Wonderful, (6)
"A little piece of heaven bursting with life on the coralreef right outside the door"
Canada
Brenda W.
$159 nightly
The price is $159
Jan 4 - Jan 5, 2026
Total with taxes and fees
Bocas Villas - Private Acqua Villas
Beach nearby
Beachfront House at La Vida Resort

Vacation Home in Bocas Del Toro

Beachfront House at La Vida Resort
8.8 out of 10, Excellent, (3)
"We had the absolute best time staying at this beach cabana. The bed was super cozy, the outdoor kitchen was awesome (make sure to bring all the food/beverages you need), the beach has the most beautiful clear water and loads of star fish and other fish and we were the ONLY people there and had the entire beach to ourselves, the locals were kind when passing and the host was extremely friendly and accommodating and had quick response to questions. We did a water taxi out there and had a pick up...
United States
Sarah W.
$331 nightly
The price is $331
Dec 28 - Dec 29
Total with taxes and fees
Beachfront House at La Vida Resort
Terrace/patio
Paradise Place - Luxury over water bungalow, king size bed, kitchen, living room

Vacation Home in Bocas del Toro

Paradise Place - Luxury over water bungalow, king size bed, kitchen, living room
2.0 star property
$920 nightly
The price is $1,001
Jan 6 - Jan 7, 2026
Total with taxes and fees
Paradise Place - Luxury over water bungalow, king size bed, kitchen, living room
Cookware/dishes/utensils
Jungle Bungalow at Bluff Beach, Bocas del Toro

Vacation Home in Bocas del Toro

Jungle Bungalow at Bluff Beach, Bocas del Toro
2.0 star property
$120 nightly
The price is $130
Dec 25 - Dec 26
Total with taxes and fees
Jungle Bungalow at Bluff Beach, Bocas del Toro
Private kitchen
Bluff Beach Bungalow Jungle Retreat

Vacation Home in Isla Colon

Bluff Beach Bungalow Jungle Retreat
2.0 star property
$120 nightly
The price is $130
Dec 25 - Dec 26
Total with taxes and fees
Bluff Beach Bungalow Jungle Retreat
Property grounds
Beach House with Pool

Vacation Home in Bocas del Toro

Beach House with Pool
2.0 star property
10.0 out of 10, Exceptional, (1)
"This home is a great space in an even greater location!!!!!! My family and I thoroughly enjoyed our short stay, and will be back!!!!!"
United States
Lauretta N.
$397 nightly
The price is $397
Jan 12 - Jan 13, 2026
Total with taxes and fees
Beach House with Pool
1 bedroom, WiFi, bed sheets
Dome shaped bungalow in a lush tropical forest, steps away from ocean views.

Vacation Home in Bocas del Toro

Dome shaped bungalow in a lush tropical forest, steps away from ocean views.
$140 nightly
The price is $147
Dec 31 - Jan 1, 2026
Total with taxes and fees
Dome shaped bungalow in a lush tropical forest, steps away from ocean views.
Interior
Oceanfront, 3-bedroom house in Secluded, Paradise

Vacation Home in Bocas del Toro

Oceanfront, 3-bedroom house in Secluded, Paradise
2.0 star property
$240 nightly
The price is $240
Dec 25 - Dec 26
Total with taxes and fees
Oceanfront, 3-bedroom house in Secluded, Paradise
Property grounds
Ocean Light Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette

Vacation Home in Bocas del Toro

Ocean Light Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette
$436 nightly
The price is $476
Jan 2 - Jan 3, 2026
Total with taxes and fees
Ocean Light Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette
Terrace/patio
Ocean Breeze Over Water Bungalow, 1 Bedroom, 1 Kingbed, 1 Living Room, 1 Kitchen

Vacation Home in Bastimentos Island

Ocean Breeze Over Water Bungalow, 1 Bedroom, 1 Kingbed, 1 Living Room, 1 Kitchen
$462 nightly
The price is $503
Dec 30 - Dec 31
Total with taxes and fees
Ocean Breeze Over Water Bungalow, 1 Bedroom, 1 Kingbed, 1 Living Room, 1 Kitchen
Interior
Seaside Dream Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette

Vacation Home in Bocas del Toro

Seaside Dream Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette
$434 nightly
The price is $474
Dec 25 - Dec 26
Total with taxes and fees
Seaside Dream Over Water Bungalow, Bedroom, King Bed, Living Room, Kitchenette
Property grounds
Over the Water - Dream Holiday House

Vacation Home in ISLA COLON

Over the Water - Dream Holiday House
2.0 star property
$629 nightly
The price is $629
Jan 21 - Jan 22, 2026
Total with taxes and fees
Over the Water - Dream Holiday House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Cayos Zapatilla Hotel Reviews

Divers Paradise Boutique Hotel

Divers Paradise Boutique Hotel

10/10 Excellent
"Food and the room were perfect "
Jean Sebastien 2-night trip
Posted 5 days ago
Divers Paradise Boutique Hotel

Find out more about Cayos Zapatilla

Cayos Zapatilla Vacation Homes information

Number of reviews
96
Accommodation
77 Vacation Homes
Lowest Price
$44
Highest Price
$629

Explore a world of travel with Expedia