Chilean Patagonia Vacations from $354

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Chilean Patagonia Vacation

Leave the travel planning to us with a Chilean Patagonia vacation package. With everything organized before you go, all you'll have to do is sit back, relax and experience this destination's many wonders. A trip to Chilean Patagonia wouldn't be complete without spending some time in its most renowned cities, starting with Puerto Natales. A couple of the top attractions here include Puerto Natales Casino and Costanera. Punta Arenas should also be on the itineraries of all Chilean Patagonia travelers. Visitors to this destination enjoy Club Andino Centro de Ski and Zona Franca Shopping Area. Whether you plan to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Chilean Patagonia vacation.

The Latest Chilean Patagonia vacation packages

Price found within the past 48 hours. Click for updated prices.
HOTEL MERCURIO
Hotel Cabo De Hornos
Hotel Jose Nogueira
Diego De Almagro Punta Arenas
Hotel Almasur Punta Arenas
Don't see what you're looking for?
See all available trips from Columbus to Chilean Patagonia
View all trips

Discover the most popular places to visit in Chilean Patagonia

What to do in Chilean Patagonia

Chilean Patagonia Hotel Deals

Rio Serrano Hotel + Spa

Rio Serrano Hotel + Spa

4 out of 5
Torres Del Paine, Sector Pueblito Serrano, Torres del Paine, Magallanes
$232 nightly
The price is $232 total per night from Sep 22 to Sep 23
$232 total
Sep 22 - Sep 23
9/10 Wonderful! (452 reviews)
"Stayed 4 nights and this is an amazing way to experience Torres Del Paine. We’d spend hours just staring at the view from the hotel. But it was also so easy to access the various hikes and sights of the park. The food was consistently good (some of the best we had on our trip through South America) ..."

Reviewed on Apr 29, 2025

Rio Serrano Hotel + Spa
Hotel Cabo De Hornos

Hotel Cabo De Hornos

3.5 out of 5
Plaza Muñoz Gamero 1039, Punta Arenas, Magallanes
$117 nightly
The price is $117 total per night from Aug 23 to Aug 24
$117 total
Aug 23 - Aug 24
8.8/10 Excellent! (527 reviews)
"Amazing"

Reviewed on Aug 14, 2025

Hotel Cabo De Hornos
Best Western Patagonia

Best Western Patagonia

3.5 out of 5
Huerto 282 Lote 11 Ruta 9, Natales, Magallanes y Antartica Chilena
$185 nightly
The price is $185 total per night from Sep 16 to Sep 17
$185 total
Sep 16 - Sep 17
8.8/10 Excellent! (37 reviews)
"Friendly staff, very clean and perfect for commuting to Torres del Paine!"

Reviewed on Apr 18, 2025

Best Western Patagonia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.