East Downtown Houston Vacations from $224

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Your East Downtown Houston Vacation

If you're craving an urban retreat, our East Downtown Houston vacation packages are the answer. Whether you want to experience its nightlife, bars and pubs or culture, this neighborhood has something for every traveler. When it's time to explore the sights, you'll find a lot of big-name attractions nearby including Toyota Center, Minute Maid Park and Downtown Aquarium. Visit one, two or more during your trip to East Downtown Houston. Expedia can put your travel plans into action. Book your dream East Downtown Houston vacation now.

The Latest East Downtown Houston Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Houston Heights I-10
Reside Houston Dwntwn, Wyndham
Luxury 3BR for Families Nurses and Group
The Laura Hotel, Houston Downtown, Autograph Collection
Holiday Inn Houston Downtown by IHG

Where to stay in East Downtown Houston

Find the best East Downtown Houston areas and neighborhoods for the activities you enjoy most. Learn more about East Downtown Houston

East Downtown Houston Hotel Deals

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Mar 22 to Mar 23
$138 total
Mar 22 - Mar 23
Total with taxes and fees
8.2/10 Very Good! (3,395 reviews)
It was a great stay the only thing was I thought I was told the shower was walk in and it wasn’t

Reviewed on Feb 21, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$289 nightly
The price is $338 total per night from Mar 15 to Mar 16
$338 total
Mar 15 - Mar 16
Total with taxes and fees
9/10 Wonderful! (1,907 reviews)
Thoughtfully designed property with perks like complimentary shuttle to/from the hotel in 3 mile radius, proximity to great museums, and little amenities like chocolates or prosecco in the room for Valentine’s Day. :)

Reviewed on Feb 16, 2026

Hotel Zaza Houston Museum District
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
$189 nightly
The price is $221 total per night from Feb 22 to Feb 23
$221 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (3,748 reviews)
The room was spacious. The evening staff was unfriendly and room have clean only had 2 big towels aand calling front desk was impossible. Text them requesting towel set afte check in never received them

Reviewed on Feb 21, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.