Name: The Mantissa Hotel
Price range: $181 total
Rating: 9

Your Darlington County Vacation

Leave all the planning up to us with a Darlington County vacation package. With everything arranged before you head off, the only thing left for you to do is sit back, relax and enjoy this destination's countless delights. Not sure where your first stop should be? Hartsville is one of the leading cities to visit during your trip to Darlington County. From the moment you book your Darlington County vacation to the second you come back home, Expedia will be with you each step of the way.

Top destinations in Darlington County

The Latest Darlington County Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Fairfield Inn by Marriott Hartsville

$666

per person

Mar 28 - Apr 4

found 4 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Florence (FLO)

8.6/10 Excellent! (668 reviews)

Amanda at the front desk was super friendly and I enjoyed talking to her and her recommendations! Room was very clean and quiet. Will stay again if in the area!

Reviewed on Jan 14, 2026

Comfort Inn & Suites Florence Center Area

$723

per person

Mar 28 - Apr 4

found 4 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Florence (FLO)

9.2/10 Wonderful! (1,145 reviews)

Nice staff, clean, , convenient location

Reviewed on Jan 13, 2026

Hyatt Place Florence Downtown

$768

per person

Mar 28 - Apr 4

found 4 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Florence (FLO)

8.8/10 Excellent! (1,001 reviews)

Breakfast service was poor, they ran out of food, plates, forks

Reviewed on Jan 11, 2026

Staybridge Suites Florence - Civic Center by IHG

$718

per person

Mar 28 - Apr 4

found 4 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Florence (FLO)

9.4/10 Exceptional! (913 reviews)

Nice place clean quiet near a lot of restaurants

Reviewed on Jan 8, 2026

Comfort Suites Florence I-95

$1,018

per person

Mar 29 - Apr 5

found 1 day ago

Roundtrip non-stop flight included

Raleigh (RDU) to Florence (FLO)

8.4/10 Very Good! (1,000 reviews)

Great accommodations and courteous staff

Reviewed on Jan 11, 2026

Find the Best Darlington County Vacation Packages

Darlington County Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Florence Regional Airport (FLO)
Top Sights	Kalmia Gardens, Segars-McKinnon Heritage Preserve and H Cooper Black Jr. Memorial Field Trial & Recreation Area

Darlington County Hotel Deals

Fairfield Inn by Marriott Hartsville

200 S 4th St Hartsville SC

Fully refundableReserve now, pay when you stay

$84 nightly

$94 total

Jan 24 - Jan 25

Total with taxes and fees

8.4/10 Very Good! (686 reviews)

This place was very clean and comfortable. Staff was fantastic. It’s very quiet and that’s what I needed.

Reviewed on Dec 27, 2025

Hampton Inn & Suites Hartsville

203 East Carolina Ave. Hartsville SC

Fully refundableReserve now, pay when you stay

$122 nightly

$137 total

Jan 23 - Jan 24

Total with taxes and fees

9.2/10 Wonderful! (483 reviews)

The staff are always friendly and the room is always fresh and clean

Reviewed on Jan 3, 2026

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

Fully refundableReserve now, pay when you stay

$162 nightly

$181 total

Jan 22 - Jan 23

Total with taxes and fees

9/10 Wonderful! (271 reviews)

Excellent staff and in the heart of a beautiful downtown.

Reviewed on Dec 5, 2025

See all 199 properties in Darlington County

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.