Cheap Flights to Khatlon Region from $143

View $143 flight on Sun, Nov 22, 2026Opens in a new window

Popular airlines to Khatlon Region

  • Turkish Airlines

  • Emirates

  • China Southern Airlines

  • Pegasus Airlines

  • Air Astana

  • Azerbaijan Airlines

  • Uzbekistan Airways

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

How much is the cheapest flight to Khatlon Region?

Prices were available within the past 7 days and start at $143 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Azerbaijan Airlines
Sun, Nov 22 - Sat, Nov 28
IST
Istanbul
DYU
Dushanbe
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select Azerbaijan Airlines flight, departing Sun, Nov 22 from Istanbul to Dushanbe, returning Sat, Nov 28, priced at $269 found 3 days ago
Azerbaijan Airlines
Sun, Nov 22 - Sat, Nov 28
IST
Istanbul
DYU
Dushanbe
$275 Roundtrip, found 3 days ago
$275
Roundtrip
found 3 days ago
Select Azerbaijan Airlines flight, departing Sun, Nov 22 from Istanbul to Dushanbe, returning Sat, Nov 28, priced at $275 found 3 days ago
Azerbaijan Airlines
Sat, May 16 - Sat, May 23
IST
Istanbul
DYU
Dushanbe
$362 Roundtrip, found 5 days ago
$362
Roundtrip
found 5 days ago
Select Azerbaijan Airlines flight, departing Sat, May 16 from Istanbul to Dushanbe, returning Sat, May 23, priced at $362 found 5 days ago
Azerbaijan Airlines
Sun, May 17 - Mon, May 25
IST
Istanbul
DYU
Dushanbe
$362 Roundtrip, found 2 days ago
$362
Roundtrip
found 2 days ago
Select Azerbaijan Airlines flight, departing Sun, May 17 from Istanbul to Dushanbe, returning Mon, May 25, priced at $362 found 2 days ago
Azerbaijan Airlines
Thu, May 21 - Mon, May 25
IST
Istanbul
DYU
Dushanbe
$402 Roundtrip, found 1 day ago
$402
Roundtrip
found 1 day ago
Select Azerbaijan Airlines flight, departing Thu, May 21 from Istanbul to Dushanbe, returning Mon, May 25, priced at $402 found 1 day ago
Azerbaijan Airlines
Sun, Nov 22 - Sat, Nov 28
SAW
Istanbul
DYU
Dushanbe
$425 Roundtrip, found 3 days ago
$425
Roundtrip
found 3 days ago
Select Azerbaijan Airlines flight, departing Sun, Nov 22 from Istanbul to Dushanbe, returning Sat, Nov 28, priced at $425 found 3 days ago
Pegasus Airlines
Mon, Jun 8 - Tue, Jun 16
SAW
Istanbul
DYU
Dushanbe
$451 Roundtrip, found 8 hours ago
$451
Roundtrip
found 8 hours ago
Select Pegasus Airlines flight, departing Mon, Jun 8 from Istanbul to Dushanbe, returning Tue, Jun 16, priced at $451 found 8 hours ago
Turkish Airlines
Fri, May 29 - Thu, Jun 4
IST
Istanbul
DYU
Dushanbe
$527 Roundtrip, found 1 day ago
$527
Roundtrip
found 1 day ago
Select Turkish Airlines flight, departing Fri, May 29 from Istanbul to Dushanbe, returning Thu, Jun 4, priced at $527 found 1 day ago
Air Astana
Fri, May 29 - Thu, Jun 4
IST
Istanbul
DYU
Dushanbe
$537 Roundtrip, found 1 day ago
$537
Roundtrip
found 1 day ago
Select Air Astana flight, departing Fri, May 29 from Istanbul to Dushanbe, returning Thu, Jun 4, priced at $537 found 1 day ago
Uzbekistan Airways
Mon, Jun 8 - Tue, Jun 16
IST
Istanbul
DYU
Dushanbe
$733 Roundtrip, found 8 hours ago
$733
Roundtrip
found 8 hours ago
Select Uzbekistan Airways flight, departing Mon, Jun 8 from Istanbul to Dushanbe, returning Tue, Jun 16, priced at $733 found 8 hours ago

Trending flights to Khatlon Region

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Emirates
Mon, May 11 - Wed, May 27
JFK
New York
DYU
Dushanbe
$1,143 Roundtrip, just found
$1,143
Roundtrip
just found
Select Emirates flight, departing Mon, May 11 from New York to Dushanbe, returning Wed, May 27, priced at $1,143 just found

Book with confidence

Enjoy extra legroom, flight flexibility, and a seamless travel experience.

Travel information

*Flight schedules are subject to change.

*Available to One Key members.

 

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia