Title: Lee County Vacation Rentals from $139: Search Short-Term Rentals | Expedia.com [Lee County Hotels](https://expedia.com/Destinations-In-Lee-County.d553248635976429778.Hotel-Destinations)[Car Rentals in Lee County](https://expedia.com/Destinations-In-Lee-County.d553248635976429778.Car-Rental-Destinations)[Lee County Vacations](https://expedia.com/Lee-County.d553248635976429778.Destination-Travel-Guides) ![The beautiful black waters of Swan Lake form the setting for the spectacular Iris Gardens. The lake is dotted with colorful islands, and wildlife is abundant. The only public park in the United States to feature all eight swan species, Swan Lake-Iris Gardens is also home to some of the nation's most intensive plantings of Japanese iris](https://images.trvl-media.com/place/6058099/38e0e801-19c8-4df4-8360-7eb9d8d85b97.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Pon Xayavong Photography ![](https://images.trvl-media.com/place/6058099/38e0e801-19c8-4df4-8360-7eb9d8d85b97.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Top Cities in Lee County ![Somewhere in rural South Carolina off a back road to my hometown. Saw the sunflower field and had to stop. ](https://images.trvl-media.com/place/3000456025/6a3c56a6-b58b-4522-a79c-15e608af44bf.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Mayesville [](https://expedia.com/Mayesville-Vacation-Rentals.d3000456025.Travel-Guide-VacationRentals) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Lee+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976429778&latLong=34.163323%2C-80.254496&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=APART_HOTEL) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Lee+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976429778&latLong=34.163323%2C-80.254496&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Lee+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976429778&latLong=34.163323%2C-80.254496&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=CONDO) Apartments [](https://www.expedia.com/Hotel-Search?destination=Lee+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976429778&latLong=34.163323%2C-80.254496&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Lee+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635976429778&latLong=34.163323%2C-80.254496&adults=2&startDate=2026-06-23&d1=2026-06-23&endDate=2026-06-26&d2=2026-06-26&lodging=COTTAGE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Lee-County.d553248635976429778.Vacation-Rental-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Lee-County.d553248635976429778.Vacation-Rental-Destinations) ## Top Lee County Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "Pleasant staff and very clean room. Comfortable sleeping quarters and very close to a variety of restaurants and shopping. Great location! " [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Fairfield Inn by Marriott Hartsville](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/1397c485_y.jpg) ### Fairfield Inn by Marriott Hartsville 8/10 Good "Easy access to Darlington Speedway" [](https://expedia.com/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) ![Fairfield Inn & Suites by Marriott Florence I-20](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 10/10 Excellent "The room was clean and tidy. Very nice staff and the breakfast in the morning was very good." [](https://expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "The breakfast was OK those eggs are disgusting. I don’t know why all of you hotels used the same type of eggs with all the peppers and onions and stuff. It’s gross. It should just be eggs plain." [](https://expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "The room wasn't as clean as my last stay there in the of last year. " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 6/10 Okay "This is a very nice hotel. The room was very clean & the bed extremely comfortable. We loved almost everything about the hotel. The first thing we found that we did not like was the person who checked us in, they were so soft-spoken that you could not hear them. Very nice & friendly just kept having to ask can you repeat that I can't hear you. Other than that, checking in was fast and easy. We did come down to having dinner & a few drinks. Well, that is where the hotel has the opportunity to really shine but did not. The bartender was also the cook! We had two drinks, a burger with fries & 6 wings, $115.00, the bun on the burger was burnt & the food was cold. It took over a hour and a half for us to get the food, after our first drink it took 20 minutes to get another one. We came down for breakfast the next morning where they seemed to have a good selection. However, the staff were too busy talking with each other to keep food out. Keep in mind there were not a whole lot of people in the breakfast area at this point. They seemed to really like bacon because they made sure that pan was slap full, but not the eggs or potatoes. If you are looking for grits or oatmeal don't waste your time, they are instant & they don't have oatmeal & the water is warm not hot, no microwave, good luck finding pepper & salt. They have a communal set, but they don't work. It is a very nice hotel but they need to work on having bartenders & cook staff if these areas if they are open." [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "Clean Room, Good A/C. Very Satisfied." [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 10/10 Excellent "The front deck clerk was awesome. I believe here name was Crystal." [](https://expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 4/10 Poor "Room was dirty and needed repairs. The walkway was clean, but areas under the desk and beds had not been cleaned in weeks. The bathroom area was acceptably clean, but needed lots of repairs and paint. The tub creaked when anyone got into it. Stayed at 2 other hotels this weekend and this was the worst, by far. The exterior area was messy, and the brekfast was limited. " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ## Find out more about Lee County ## Discover your perfect Lee County vacation rental with Expedia #### How many vacation rentals are available in Lee County? Expedia has plenty of vacation rentals to choose from in and around Lee County, so you’re guaranteed to find the right one for you. #### How much is a vacation rental in Lee County? The selection of Lee County vacation rentals we have selected for you start as low as $139 per night. Entering your travel dates in the search wizard you might find even better deals! #### What type of vacation rental can I get in Lee County? Vacation rentals in Lee County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Lee County vacation rentals to suit everyone. #### Why should I choose a vacation rental in Lee County? Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Lee County vacation rental often works out to be a fantastic, cost-effective option for [groups](https://www.expedia.com/lp/b/vr/large) and [families](https://www.expedia.com/lp/b/vr/family) visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. #### How do I find the best deal on a vacation rental in Lee County? Find vacation rentals in Lee County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Lee County. #### What amenities are available in a vacation rental in Lee County? The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a [swimming pool](https://www.expedia.com/lp/b/vr/private-pool) is more your thing. Of course, there’s always the treat of having [your own hot tub](https://www.expedia.com/lp/b/vr/hot-tub). Expedia has a vast range of amenities in Lee County vacation rentals designed to suit every budget and trip type. #### When is the best time to stay in a vacation rental in Lee County? Everytime is a great time to head to Lee County! Staying in a Lee County vacation rentals you will always find lots going on to keep you entertained. #### Why book a vacation rental with Expedia? Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Lee County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Lee County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Lee County, you can save even more. #### Can I cancel my vacation rental through Expedia? Yes, you can cancel or change your Lee County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted. ## Explore a world of travel with Expedia - Popular Lee County Cities - All accommodation types in Lee County - [Bishopville Vacation Rentals ](https://expedia.com/Bishopville-Vacation-Rentals.d6938.Travel-Guide-VacationRentals) - [Vacation Homes in Lee County ](https://expedia.com/Lee-County-Private-Vacation-Homes.d553248635976429778-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Motels in Lee County ](https://expedia.com/Lee-County-Motels.d553248635976429778-aaMotels.Travel-Guide-Accommodation) - [Cottages in Lee County ](https://expedia.com/Lee-County-Cottages.d553248635976429778-aaCottages.Travel-Guide-Accommodation) - [Apartments in Lee County ](https://expedia.com/Lee-County-Apartments.d553248635976429778-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Lee County ](https://expedia.com/Lee-County-Condos.d553248635976429778-aaCondos.Travel-Guide-Accommodation) - [Farmstay in Lee County ](https://expedia.com/Lee-County-Agritourism.d553248635976429778-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Lee County ](https://expedia.com/Lee-County-Bed-And-Breakfast.d553248635976429778-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Lee County ](https://expedia.com/Lee-County-Cabins.d553248635976429778-aaCabins.Travel-Guide-Accommodation) - [Aparthotels in Lee County ](https://expedia.com/Lee-County-Apart-Hotels.d553248635976429778-aaApartHotels.Travel-Guide-Accommodation)