A swamp with tall trees, water, and swans.

Vacation Rentals in Lee County

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Top Cities in Lee County

A sunflower in a field with a dirt path and trees in the background.
Vacation RentalsVacation Rentals

Mayesville

Mayesville

Our top choices for Lee County vacation rentals

A compact kitchen with white cabinets, a wooden countertop, a built-in microwave, and a refrigerator.

1. Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (70 reviews)
"The location really is the highlight and the bed is excellent. "
United States
Paul C.
$159 nightly
The price is $178
Oct 14 - Oct 15
Total with taxes and fees
Camden Cottage
A brick pathway leading to a white building with a porch and a door labeled "Around Entrance."

2. Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Camden
10.0 out of 10, Exceptional, (19 reviews)
"Great place would definitely return"
United States
Brent U.
$134 nightly
The price is $150
Oct 13 - Oct 14
Total with taxes and fees
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
A bedroom with a sloped ceiling, skylight, wooden flooring, and a bed with pillows and a blanket.

3. Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Camden
10.0 out of 10, Exceptional, (10 reviews)
"Beautiful property. Cozy and quiet."
United States
Doug K.
$170 nightly
The price is $190
Oct 11 - Oct 12
Total with taxes and fees
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
A modern office space with a desk, chair, TV, and shelves.

4. 1 King Bed|Smoking|Lugoff, SC

1 King Bed|Smoking|Lugoff, SC
Lugoff
10.0 out of 10, Exceptional, (3 reviews)
"I'd suggest this spot to travelers stopping through. Quick check-in, comfy bed, and a nice tub after long drives made it worth staying here."
United States
Anonymous traveler
$68 nightly
The price is $76
Oct 11 - Oct 12
Total with taxes and fees
1 King Bed|Smoking|Lugoff, SC
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

5. The Urban Flats

The Urban Flats
4.0 star property
Florence
$383 nightly
The price is $429
Oct 14 - Oct 15
Total with taxes and fees
The Urban Flats
A kitchen with white cabinets, a central island, a chandelier, and a dining table with stools.

6. Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Rembert
9.4 out of 10, Exceptional, (40 reviews)
"Enjoyed our time and we are looking forward to being back there in August. Already have it scheduled. Wife's birthday!"
United States
david g.
$222 nightly
The price is $248
Oct 8 - Oct 9
Total with taxes and fees
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
A room with a window, a television, and a cabinet.

7. The Sunny Cottage minutes to downtown

The Sunny Cottage minutes to downtown
Florence
$169 nightly
The price is $190
Oct 8 - Oct 9
Total with taxes and fees
The Sunny Cottage minutes to downtown
A reception desk with a computer, a blue chair, and a colorful wall decoration.

8. 1 King Bed | Non-Smoking

1 King Bed | Non-Smoking
Lugoff
10.0 out of 10, Exceptional, (3 reviews)
"My stay included a restful spot with good air conditioning that ensured peaceful nights without any interruptions."
United States
Anonymous traveler
$68 nightly
The price is $76
Oct 11 - Oct 12
Total with taxes and fees
1 King Bed | Non-Smoking
A reception desk with a computer, a blue chair, and a colorful wall decoration.

9. 2 Queen Beds | Non-Smoking

2 Queen Beds | Non-Smoking
Lugoff
10.0 out of 10, Exceptional, (3 reviews)
"Staff at reception processed our check-ins quickly every time we arrived!"
United States
Anonymous traveler
$77 nightly
The price is $87
Oct 11 - Oct 12
Total with taxes and fees
2 Queen Beds | Non-Smoking
A hotel room with a bed, a nightstand, a phone, and a window with curtains.

10. 1 King Bed | Smoking, Micfridge

1 King Bed | Smoking, Micfridge
Lugoff
10.0 out of 10, Exceptional, (2 reviews)
"The bed gave firm support but stayed pleasant all through the night."
United States
Anonymous traveler
$74 nightly
The price is $82
Oct 11 - Oct 12
Total with taxes and fees
1 King Bed | Smoking, Micfridge
A hotel room with a bed, a desk with a chair, a television, and a mirror.

11. 2 Queen Beds | Smoking

2 Queen Beds | Smoking
Lugoff
10.0 out of 10, Exceptional, (2 reviews)
"Simple setup yet very practical accommodations overall"
United States
Anonymous traveler
$77 nightly
The price is $87
Oct 11 - Oct 12
Total with taxes and fees
2 Queen Beds | Smoking
A dining area with a wooden table and chairs, a chandelier, and a large mirror on the wall.

12. Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.4 out of 10, Very good, (5 reviews)
"Convenient location"
United States
Bonney W.
$455 nightly
The price is $510
Oct 25 - Oct 26
Total with taxes and fees
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
A cabin with a deck, outdoor seating, a fire pit, and a staircase leading to a second level.

13. Horizons Sandhills

Horizons Sandhills
3.5 star property
Patrick
$459 nightly
The price is $500
Oct 8 - Oct 9
Total with taxes and fees
Horizons Sandhills
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lee County Hotel Reviews

Florence Inn and Suites

Florence Inn and Suites

8/10 Good
"El cuarto fue limpiado y entregado impecable, sin malos olores y sin olor a polvo. El aire acondicionado estaba en excelente condición y el ambiente se sentía fresco. Solo no me gustó que el manager me levantara para verificar el cable y la televisión cuestiones que no entendí porque el cuarto debe entregarse con estos servicios listos para funcionar, además nunca los utilice. Escale la queja, me dijeron que ese era el property manager… les repetí que porque el hacía eso y ellos me repetían que era el property manager y podía hacerlo… lo cual me pareció descortés que interrumpiera mi sueño en favor de sus intereses y los del hotel. Sábanas cobijas y almohadas estaban limpias y en buen estado, la cama fue cómoda también. The room was cleaned and delivered spotless, without bad smells and without the smell of dust. The air conditioning was in excellent condition and the atmosphere felt fresh. I just didn't like that the manager picked me up to check the cable and television issues that I didn't understand because the room must be delivered with these services ready to work, besides I never used them. Escalate the complaint, they told me that that was the property manager... I repeated that because he did that and they repeated to me that he was the property manager and could do it... which seemed impolite to me that he interrupted my sleep in favor of his interests and those of the hotel. Sheets blankets and pillows were clean and in good condition, the bed was comfortable to"
Javier 4-night trip
Posted 2 hours ago
Florence Inn and Suites

Find out more about Lee County

Discover your perfect Lee County vacation rental with Expedia

How many vacation rentals are available in Lee County?


Expedia has plenty of vacation rentals to choose from in and around  Lee County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Lee County?


The selection of Lee County vacation rentals we have selected for you start as low as $150 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Lee County?


Vacation rentals in Lee County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Lee County vacation rentals to suit everyone. 


Why should I choose a vacation rental in Lee County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Lee County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Lee County?


Find vacation rentals in Lee County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Lee County.  


What amenities are available in a vacation rental in Lee County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Lee County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Lee County?   


Everytime is a great time to head to Lee County! Staying in a Lee County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Lee County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Lee County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Lee County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Lee County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.